Sequence polymorphism systems for quantitative real-time polymerase chain reaction to characterize hematopoietic chimerism - High informativity and sensitivity as well as excellent reproducibility and precision of measurement

Laboratory Hematology

Volumn 13, Issue 3, 2007, Pages 73-84

  Willasch, Andre ^a   Schneider, Gaby ^b   Reincke, Britta Sofia ^a   Shayegi, Nona ^a   Kreyenberg, Hermann ^a   Kuci, Selim ^a   Weber, Gerrit ^a   van der Reijden, Bert ^c   Niethammer, Dietrich ^d   Klingebiel, Thomas ^a   Bader, Peter ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Allogeneic transplantation; Chimerism; Sequence polymorphisms; Single nucleotide polymorphisms Real time PCR

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; ALLOGENEIC STEM CELL TRANSPLANTATION; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CHILD; CHIMERA; DIAGNOSTIC ACCURACY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MOUSE; MYELODYSPLASTIC SYNDROME; NONHUMAN; QUANTITATIVE ANALYSIS; RECIPIENT; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; ADOLESCENT; ADULT; ALLOTRANSPLANTATION; DIAGNOSIS, MEASUREMENT AND ANALYSIS; EVALUATION; GENETIC MARKER; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; INFANT; MALE; METHODOLOGY; NEWBORN; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CLINICAL LABORATORY TECHNIQUES; FEMALE; GENETIC MARKERS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; INFANT, NEWBORN; MALE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS;

EID: 38449118406     PISSN: 10802924     EISSN: None     Source Type: Journal    
DOI: 10.1532/LH96.07004     Document Type: Article

References (35)

1. Lion T, Daxberger H, Dubovsky J, et al. Analysis of chimerism within specific leukocyte subsets for detection of residual or recurrent leukemia in pediatric patients after allogeneic stem cell transplantation. Leukemia. 2001;15:307-310.
2. Lion T, Muller-Berat N. Chimerism testing after allogeneic stem cell transplantation: importance of timing and optimal technique for chimerism testing in different clinical-biological situations. Leukemia. 1999;13:2059.
3. Bader P, Kreyenberg H, Hoelle W, et al. Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell transplantation: possible role for pre-emptive immunotherapy? J Clin Oncol. 2004;22:1696-1706.
4. Acquaviva C, Duval M, Mirebeau D, Bertin R, Cave H. Quantitative analysis of chimerism after allogeneic stem cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with fluorescence detection: the Paris-Robert Debre experience. Leukemia. 2003;17:241-246.
5. Bader P, Niemeyer C, Willasch A, et al. Children with myelodysplastic syndrome (MDS) and increasing mixed chimaerism after allogeneic stem cell transplantation have a poor outcome which can be improved by pre-emptive immunotherapy. Br J Haematol. 2005;128:649-658.
6. Yoshimi A, Bader P, Matthes-Martin S, et al. Donor leukocyte infusion after hematopoietic stem cell transplantation in patients with juvenile myelomonocytic leukemia. Leukemia. 2005;19:971-977.
7. Bader P, Klingebiel T, Schaudt A, et al. Prevention of relapse in pediatric patients with acute leukemias and MDS after allogeneic SCT by early immunotherapy initiated on the basis of increasing mixed chimerism: a single center experience of 12 children. Leukemia. 1999;13(12):2079-2086.
8. Baron F, Sandmaier BM. Chimerism and outcomes after silogeneic hematopoietic cell transplantation following nonmyeloablative conditioning (review). Leukemia. 2006;20:1690-1700.
9. Lion T. Summary: reports on quantitative analysis of chimerism after allogeneic stem cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with fluorescence detection. Leukemia. 2003;17(1):252-254.
10. Kreyenberg H, Holle W, Mohrle S, Niethammer D, Bader P. Quantitative analysis of chimerism after allogeneic stem cell transplantation by PCR amplification of microsatellite markers and capillary electrophoresis with fluorescence detection: the Tuebingen experience. Leukemia. 2003;17(1):237-240.
11. Thiede C, Bornhauser M, Ehninger G. Evaluation of STR informativity for chimerism testing-comparative analysis of 27 STR systems in 203 matched related donor recipient pairs. Leukemia. 2004;18(2):248-254.
12. Watzinger F, Lion T, Steward C. The RSD code: proposal for a nomenclature of allelic configurations in STR-PCR-based chimerism testing after allogeneic stem cell transplantation. Leukemia. 2006;20(8):1448-1452.
13. Muller-Berat N, Lion T. Chimerism and transplant-related diagnostics. Leukemia. 2006;20(8):1358-1360.
14. Lion T, Muller-Berat N. Chimerism testing after allogeneic stem cell transplantation: importance of timing and optimal technique for testing in different clinical-biological situations. Leukemia. 2003;17(3):612.
15. Thiede C, Bornhauser M, Oelschlagel U, et al. Sequential monitoring of chimerism and detection of minimal residual disease after allogeneic blood stem cell transplantation (BSCT) using multiplex PCR amplification of short tandem repeat-markers. Leukemia. 2001;15(2):293-302.
16. Sachidanandam R, Weissman D, Schmidt SC, et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature. 2001;409(6822):928-933.
17. Wang DG, Fan JB, Siao, et al. Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science. 1998;280(5366):1077-1082.
18. Hochberg EP, Miklos DB, Neuberg D, et al. A novel rapid single nucleotide polymorphism (SNP)-based method for assessment of hematopoietic chimerism after allogeneic stem cell transplantation. Blood. 2003;101(1):363-369.
19. Bader P, Kreyenberg H, Hoelle W, et al. Increasing mixed chimerism defines a high-risk group of childhood acute myelogenous leukemia patients after allogeneic stem cell transplantation where pre-emptive immunotherapy may be effective. Bone Marrow Transplant. 2004;33(8):815-821.
20. Bader P, Niethammer D, Willasch A, Kreyenberg H, Klingebiel T. How and when should we monitor chimerism after allogeneic stem cell transplantation? Bone Marrow Transplant. 2005;35(2):107-119.
21. Pongers-Willemse MJ, Verhagen OJ, Tibbe GJ, et al. Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific Taq-Man probes. Leukemia. 1998;12(12):2006-2014.
22. Alizadeh M, Bernard M, Danic B, et al. Quantitative assessment of hematopoietic chimerism after bone marrow transplantation by real-time quantitative polymerase chain reaction. Blood. 2002;99(12):4618-4625.
23. Maas F, Schaap N, Kolen S, et al. Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms. Leukemia. 2003;17(3):621-629.
24. Maas F, Schaap N, Kolen S, et al. Quantification of donor and recipient hemopoietic cells by real-time PCR of single nucleotide polymorphisms. Leukemia. 2003;17(3):630-633.
25. Maas F, Schaap N, Kolen S, et al. Corrigendum - Quantification of donor and recipient hemopoietic cells by real-time PCR of single-nucleotide polymorphisms. Leukemia. 2004;18:663.
26. van der Velden VH, Hochhaus A, Cazzaniga G, Szczepanski T, Gabert J, van Dongen JJ. Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects. Leukemia. 2003;17(6):1013-1034.
27. The R Foundation for Statistical Computing c/o Institut für Statistik und Wahrscheinlichkeitstheorie der Technischen Universität Wien. R, a language and environment for statistical computing and graphics. 2003.
28. Formankova R, Honzatkova L, Sieglova Z, Stary J, Sedlacek P, Brdicka R. Detailed monitoring of hematopoietic chimerism in a child treated by adoptive immunotherapy for high risk of relapse after BMT for acute myeloid leukemia. Bone Marrow Transplant. 2000;25(4):453-456.
29. Gorczynska E, Turkiewicz D, Toporski J, et al. Prompt initiation of immunotherapy in children with an increasing number of autologous cells after allogeneic HCT can induce complete donor-type chimerism: a report of 14 children. Bone Marrow Transplant. 2004;33(2):211-217.
30. Fernandez-Aviles F, Urbano-Ispizua A, Aymerich M, et al. Serial quantification of lymphoid and myeloid mixed chimerism using multiplex PCR amplification of short tandem repeat-markers predicts graft rejection and relapse, respectively, after allogeneic transplantation of CD34+ selected cells from peripheral blood. Leukemia. 2003;17(3):613-620.
31. Zeiser R, Spyridonidis A, Wasch R, et al. Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative allogeneic hematopoietic cell transplantation. Leukemia. 2005;19(5):814-821.
32. Thiede C, Bornhauser M, Ehninger G. Strategies and clinical implications of chimerism diagnostics after allogeneic hematopoietic stem cell transplantation. Acta Haematol. 2004;112:16-23.
33. Kroger N, Zagrivnaja M, Schwartz S, et al. Kinetics of plasma-cell chimerism after allogeneic stem cell transplantation by highly sensitive real-time PCR based on sequence polymorphism and its value to quantify minimal residual disease in patients with multiple myeloma. Exp Hematol. 2006;34(5):688-694.
34. Jimenez-Velasco A, Barrios M, Roman-Gomez J, et al. Reliable quantification of hematopoietic chimerism after allogeneic transplantation for acute leukemia using amplification by real-time PCR of null alleles and insertion/deletion polymorphisms. Leukemia. 2005;19(3):336-343.
35. Koldehoff M, Steckel NK, Hlinka M, Beelen DW, Elmaagacli AH. Quantitative analysis of chimerism after allogeneic stem cell transplantation by real-time polymerase chain reaction with single nucleotide polymorphisms, standard tandem repeats and Y-chromosome-specific sequences. Am J Hematol. 2006; 81(10):735-746.