The significance of family history in first-episode schizophrenia spectrum disorder

Journal of Nervous and Mental Disease

Volumn 195, Issue 10, 2007, Pages 846-852

  Norman, Ross M G ^a,c   Manchanda, Rahul ^a   Malla, Ashok K ^b   Harricharan, Raj ^a   Northcott, Sandra ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c NONE   (Canada)

Author keywords

Family history; Intellectual functioning; Outcome; Schizophrenia

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ELECTROENCEPHALOGRAPHY; FAMILY HISTORY; FEMALE; HUMAN; INTELLECT; MALE; SCHIZOPHRENIA; SYMPTOM; CANADA; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FAMILY; FAMILY HEALTH; FOLLOW UP; INTELLIGENCE TEST; ONSET AGE; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; SEX DIFFERENCE; SOCIAL ADAPTATION; STATISTICS; TREATMENT OUTCOME;

NEUROLEPTIC AGENT;

AGE OF ONSET; ANTIPSYCHOTIC AGENTS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; ELECTROENCEPHALOGRAPHY; FAMILY; FAMILY HEALTH; FOLLOW-UP STUDIES; HUMANS; INTELLIGENCE TESTS; ONTARIO; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SEX FACTORS; SOCIAL ADJUSTMENT; TREATMENT OUTCOME;

EID: 38449101127     PISSN: 00223018     EISSN: None     Source Type: Journal    
DOI: 10.1097/NMD.0b013e318156f8e2     Document Type: Article

References (55)

1. Albus M, Scherer J, Hueber S, Lechleuthner T, Kraus G, Zausinger S, Burkes S (1994) The impact of familial loading on gender differences in age of onset of schizophrenia. Acta Psychiatr Scand. 89:132-134.
2. Alda M, Ahrens B, Lit W, Dvorakova M, Labelle A, Zvolsky P, Jones B (1996) Age of onset in familial and sporadic schizophrenia. Acta Psychiatr Scand. 93:447-450.
3. Andreasen NC (1983) The Scale for the Assessment of Negative Symptoms (SANS). Iowa City (IA): University of Iowa.
4. Andreasen NC (1984) The Scale for the Assessment of Positive symptoms (SAPS). Iowa City (IA): University of Iowa.
5. Andreasen NC, Rice J, Endicott J, Reich T, Coryell W (1986) The family history approach to diagnosis. Arch Gen Psychiatry. 43:421-429.
6. Arajarvi R, Tepp V, Haukka J, Suvisaari J, Suokas J, Juvonen H, Muhonen M, Suominen K, Hintikka J, Schreck M, Tuulio-Henriksson A, Partonen T, Lonngvist J (2006) Affective flattening and alogia associated with the familial form of schizophrenia. Psychiatry Res. 141:161-172.
7. Baron M, Grven R, Asnin L (1982) Schizophrenia: A comparative study of patients with and without family history. Br J Psychiatry. 140:516-517.
8. Becker M, Diamond R, Sainfort F (1993) A new patient focused index for measuring quality of life in persons with severe and persistent mental illness. Qual Life Res. 2:239-251.
9. Cannon-Spoor HE, Potkin SG, Wyatt RJ (1982) Measurement of premorbid adjustment in chronic schizophrenia. Schizophr Bull. 8:470-484.
10. Cardno AG, Thomas K, McGuffin P (2002) Clinical variables and genetic loading for schizophrenia: Analysis of published Danish adoption study data. Schizophr Bull. 28:393-399.
11. Castle DJ, Murray RM (1991) The neurodevelopmental basis of sex differences in schizophrenia. Psychol Med. 21:565-575.
12. Chanpattana W, Chakrabhand MLS (2001) Combined ECT and neuroleptic therapy in treatment-refractory schizophrenia: Prediction of outcome. Psychiatry Res. 105:107-115.
13. Docherty NM, Grosh ES, Wexler BE (1996) Affective reactivity of cognitive functioning and family history of schizophrenia. Biol Psychiatry. 39:59-64.
14. Feldman R, Hornung WP, Buchkremer G, Arolt V (2001) The influence of familial loading on the course of schizophrenic symptoms and the success of psychoeducational outcome. Psychopathology. 34:192-197.
15. First MB, Spitzer RL, Gibbon M, Williams JB (1995) Structured Clinical Interview of DSM-IV Axis I (SCIDI). New York (NY): Biometrics Research Department, New York State Psychiatric Institute.
16. Foerster A, Lewis SW, Owen MJ, Murray RM (1991) Low birth weight and family history of schizophrenia predict poor premorbid functioning in schizophrenia. Schizophr Res. 5:13-20.
17. Ganev K (2000) Long-term trends of symptoms and disability in schizophrenia and related disorder. Soc Psychiatry Psychiatr Epidemiol. 35:389-395.
18. Goldstein JM, Farone SV, Chen WJ, Tolomiczencko GS, Tsuang MJ (1990) Sex differences in the familial transmission of schizophrenia. Br J Psychiatry. 156:819-826.
19. Gottesman I (1991) Schizophrenia Genesis: The Origins of Madness. New York: Freeman.
20. Green MF (1996) What are the functional consequences of neurocognitive deficits in schizophrenia. Am J Psychiatry. 153:321-330.
21. Häfner H, Riecher-Rössler A, Ambrecht M, Maurer K, Meissner S, Schmidtte A, Fatkenheuer B, Loffler W, van der Heiden W (1992) IRAOS: An instrument for the assessment of onset and early course of schizophrenia. Schizophr Res. 6:209-223.
22. Harrison G, Hopper K, Crait T, Laska E, Siegel C, Wanderling J, Dube KC, Ganev K, Giel R, van der Heiden W, Holmberg SK, Janca A, Lee PW, Leon CA, Malhotra S, Marsella AJ, Nakane Y, Sartorius N, Shen Y, Skoda C, Thara R, Tsirkin SJ, Jarma VK, Walsh D, Wiersma D (2001) Recovery from psychotic illness: A 15-25-year international follow-up study. Br J Psychiatry. 178:506-517.
23. Jarbin H, Ott Y, von Knorring AL (2003) Adult outcome of social functioning in adolescent-onset schizophrenia and affective psychosis. J Am Acad Child Adolesc Psychiatry. 42:176-183.
24. Joober R, Rouleau G, Lal S, Bloom D, La Londe P, Labelle A, Benkelfat C (2005) Increased prevalence of schizophrenia spectrum disorders in relatives of neuroleptic-nonresponsive schizophrenia patients. Schizophr Res. 77:35-41.
25. Kendler KS, Karkowski-Shuman L, Walsh P (1996) Age at onset in schizophrenia and risk of illness in relatives. Br J Psychiatry. 169:213-218.
26. Kirkpatrick B, Castle D, Murray RM, Carpenter WT Jr (2000) Risk factors for the deficit syndrome of schizophrenia. Schizophr Bull. 26:233-242.
27. Lewis SW, Reveley AM, Reveley MA, Chitkara B, Murray RM (1987) The familial/sporadic distinction as a strategy in schizophrenia research. Br J Psychiatry. 151:306-313.
28. Malaspina D, Friedman JH, Kaufmann C, Bruder G, Amador X, Strauss D, Clark S, Yale S, Lukens E, Thorning H, Goetz R, Gorman J (1998) Psychobiological heterogeneity of familial and sporadic schizophrenia. Biol Psychiatry. 43:489-496.
29. Malaspina D, Goetz RR, Yale S, Berman A, Friedman JH, Tremeau F, Printz D, Amandor X, Johnson J, Brown A, Gorman JM (2000) Relation of familial schizophrenia to negative symptoms but not to the deficit syndrome. Am J Psychiatry. 157:994-1003.
30. Malla AK, Norman RMG, Manchanda R, Townsend L (2002) Symptoms, cognition, treatment adherence and functional outcome in first-episode psychosis. Psychol Med. 32:1109-1119.
31. Malla AK, Norman RMG, McLean T, Scholten D, Townsend L (2003) A Canadian programme for early intervention in non-affective disorders. Aust NZ J Psychiatry. 37:407-413.
32. Manchanda R, Norman RMG, Malla AK, Harricharan R, Northcott S (2005a) Persistent psychosis in first episode patients. Schizophr Res. 80:113-116.
33. Manchanda R, Norman RMG, Malla AK, Harricharan R, Takhar J, Northocott S (2005b) EEG abnormalities and two-year outcome in first episode psychosis. Acta Psychiatr Scand. 111:208-213.
34. Mayo Clinic (1991) Clinical Examination in Neurology (Chapter 15). Rochester (MN): Rochester Mayo Clinic and Mayo Foundation for Medical Education and Research.
35. Nasrallah HA, Kuperman S, Hamra BJ, McCalley-Whitter M (1983) Clinical differences between schizophrenic patients with and without large cerebral ventricles. J Clin Psychiatry. 44:407-409.
36. Neumann CS, Grimes K, Walker EF, Brum K (1995) Developmental pathways to schizophrenia: Behavioural subtypes. J Abnorm Psychol. 104:558-556.
37. Nimgaonkar VL, Wessely S, Tune LE, Murray RM (1988) Response to drugs in schizophrenia: The influence of family history, obstetric complications and ventricular enlargement. Psychol Med. 18:583-592.
38. Norman R, Malla AK (2001) Family history of schizophrenia and the relationship of stress to symptoms: Preliminary findings. Aus NZ J Psychiatry. 35:217-223.
39. Norman RMG, Malla AK, Manchanda R, Townsend L (2005) Premorbid adjustment in first episode schizophrenia and schizoaffective disorders: A comparison of social and academic domains. Acta Psychiatr Scand. 112:30-39.
40. Riecher-Rössler A, Häfner H (2000) Gender aspects in schizophrenia: Bridging the border between social and biological psychiatry. Acta Psychiatr Scand. 102(suppl 407):58-62.
41. Ritsner M, Ratner Y, Gibel A, Weizman R (2005) Familiality in a five-factor model of schizophrenia: Findings from a 16-month follow-up study. Psychiatry Res. 136:173-179.
42. Roy M-A, Crowe RR (1994) Validity of the familial and sporadic subtypes of schizophrenia. Am J Psychiatry. 151:805-814.
43. Roy M-A, Flaum MA, Gupta S, Jaramillo L, Andreasen NC (1994) Epidemiological and clinical correlates of familial and sporadic schizophrenia. Acta Psychiatr Scand. 89:324-328.
44. Schurhoff F, Szoke A, Bellivier F, Turcas C, Villemur M, Tignol J, Rouillon F, Leboyer M (2003) Anhedonia in schizophrenia: A distinct familial subtype? Schizophr Res. 61:89-66.
45. Shimizu A, Kurachi M (1989) Do women without a family history of schizophrenia have a later onset of schizophrenia? Jpn J Psychiatry Neurol. 43:133-136.
46. Silverman JM, Mohs RC, Davidson M, Losonczy MF, Keefe RS, Breitnor JC, Sorokin JE, Davis KL (1987) Familial schizophrenia and treatment response. Am J Psychiatry. 144:1271-1276.
47. St. Hilaire A, Holowka D, Cunningham H, Champagne F, Pukall M, King S (2005) Explaining variation in premorbid adjustment of schizophrenia patients: The role of season of birth and family history. Schizophr Res. 73:39-48.
48. Tabarés-Seisdedos R, Balanza-Martinez V, Salazar-Fraile J, Selva-Vera G, Leal-Cercos C, Gómes-Beneyto M (2003) Specific executive/attentional deficits in patients with schizophrenia or bipolar disorder who have a positive family history of psychosis. J Psychiatr Res. 37:479-486.
49. Van Kammen DP, Kelley ME, Gilbertson MW, Gurklis JA, O'Connor DT (1994) CSF dopamine B-hydroxyls in schizophrenia: Associations with premorbid functioning and brain computerized tomography scan measures. Am J Psychiatry. 151:372-378.
50. van Os J, Marcelis M, Sham P, Jones P, Gilvarry K, Murray R (1997) Psychopathological syndromes and familial morbid risk of psychosis. Br J Psychiatry. 170:241-246.
51. Verdoux H, van Os J, Sham P, Jones P, Gilvarry K, Murray RM (1996) Does familiality predispose to both emergence and persistence of psychosis? A follow-up study. Br J Psychiatry. 168:620-626.
52. Walker E, Shaye R (1982) Familial schizophrenia: Abnormalities in schizophrenia. Arch Gen Psychiatry. 39:1153-1156.
53. Wechsler D (1997) Wechsler Adult Intelligence Scale (3rd ed). New York: Psychological Corporation.
54. Wieselgren I-M, LindstrÖm LH (1996) A prospective 1-5 year outcome study in first-admitted and readmitted schizophrenic patients: Relationship to heredity, premorbid adjustment, duration of disease and education level at index admission and neuroleptic treatment. Acta Psychiatr Scand. 93:9-19.
55. Wolitzky R, Goudsmit N, Goetz RR, Printz D, Gil R, Harkavy-Friedman J, Malaspina D (2006) Etiological heterogeneity and intelligence test scores in patients with schizophrenia. J Clin Exp Neuropsychol. 28:167-177.