Increased prevalence of schizophrenia spectrum disorders in relatives of neuroleptic-nonresponsive schizophrenic patients

Schizophrenia Research

Volumn 77, Issue 1, 2005, Pages 35-41

  Joober, Ridha ^a   Rouleau, Guy A ^c   Lal, Samarthji ^a   Bloom, David ^a   Lalonde, Pierre ^d   Labelle, Alain ^e   Benkelfat, Chawki ^b  

^a MCGILL UNIVERSITY   (Canada)

^b Allan Memorial Institute   (Canada)

^c MONTREAL GENERAL HOSPITAL   (Canada)

^d CENTRE DE RECHERCHE FERNAND SEGUIN   (Canada)

^e ROYAL OTTAWA HOSPITAL   (Canada)

Author keywords

Family history; Response to neuroleptics; Schizophrenia

Indexed keywords

ADULT; CLUSTER ANALYSIS; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENETIC ANALYSIS; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; MORBIDITY; PERSONALITY DISORDER; PREVALENCE; PRIORITY JOURNAL; RELATIVE; RISK ASSESSMENT; SCHIZOPHRENIA;

EID: 21844471308     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2005.01.008     Document Type: Conference Paper

References (14)

1. H.D. Brenner, S.J. Dencker, M.J. Goldstein, J.W. Hubbard, D.L. Keegan, G. Kruger, F. Kulhanek, R.P. Liberman, U. Malm, and K.K. Midha Defining treatment refractoriness in schizophrenia Schizophr. Bull. 16 1990 551 561
2. T.B. Cooper Neuroleptic responsive versus resistant patients Contemporary issues in the treatment of schizophrenia 1995 American Psychiatric Press Washington, DC
3. J. Endicott, R.L. Spitzer, J.L. Fleiss, and J. Cohen The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance Arch. Gen. Psychiatry 33 1976 766 771
4. J. Galdi, R.O. Rieder, D. Silber, and R.R. Bonato Genetic factors in the response to neuroleptics in schizophrenia: a psychopharmacogenetic study Psychol. Med. 11 1981 713 728
5. D.L. Garver, K. Kelly, K.A. Fried, M. Magnusson, and J. Hirschowitz Drug response patterns as a basis of nosology for the mood-incongruent psychoses (the schizophrenias) Psychol. Med. 18 1988 873 885
6. R. Joober, G.A. Rouleau, S. Lal, M. Dixon, G. O'Driscoll, R. Palmour, L. Annable, D. Bloom, P. Lalonde, A. Labelle, and C. Benkelfat Neuropsychological impairments in neuroleptic-responder vs. -nonresponder schizophrenic patients and healthy volunteers Schizophr. Res. 53 2002 229 238
7. J. Kane, G. Honigfeld, J. Singer, and H. Meltzer Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine Arch. Gen. Psychiatry 45 1988 789 796
8. E. Maxwell Family interview for genetic studies NIMH 1992 (Ref type: serial (Book, Monograph))
9. M. McGue, I.I. Gottesman, and D.C. Rao The transmission of schizophrenia under a multifactorial threshold model Am. J. Hum. Genet. 35 1983 1161 1178
10. C.D. Miller Nam-Pwers Scale C.D. Miller Handbook of research design and social measurement 1991 Sage Publications Newbury Park, CA
11. M.A. Roy, D. Walsh, and K.S. Kendler Accuracies and inaccuracies of the family history method: a multivariate approach Acta Psychiatr. Scand. 93 1996 224 234
12. J.M. Silverman, R.C. Mohs, M. Davidson, M.F. Losonczy, R.S. Keefe, J.C. Breitner, J.E. Sorokin, and K.L. Davis Familial schizophrenia and treatment response Am. J. Psychiatry 144 1987 1271 1276
13. H. Verdoux, O.J. van, P. Sham, P. Jones, K. Gilvarry, and R. Murray Does familiality predispose to both emergence and persistence of psychosis? A follow-up study Br. J. Psychiatry 168 1996 620 626
14. A. Wolkin, F. Barouche, A.P. Wolf, J. Rotrosen, J.S. Fowler, C.Y. Shiue, T.B. Cooper, and J.D. Brodie Dopamine blockade and clinical response: evidence for two biological subgroups of schizophrenia Am. J. Psychiatry 146 1989 905 908