Protein engineering of nitrilase for chemoenzymatic production of glycolic acid

Biotechnology and Bioengineering

Volumn 99, Issue 3, 2008, Pages 717-720

  Wu, Shijun ^a   Fogiel, Arthur J ^a   Petrillo, Kelly L ^a   Jackson, Raymond E ^a   Parker, Kimberley N ^a   DiCosimo, Robert ^a   Ben Bassat, Arie ^a   O'Keefe, Daniel P ^a   Payne, Mark S ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Biocatalyst development; Glycolic acid; Nitrilase; Protein engineering

Indexed keywords

BIOCATALYST DEVELOPMENT; GLYCOLIC ACID; GLYCOLONITRILE; NITRILASE; PROTEIN ENGINEERING;

BIOCATALYSTS; ESCHERICHIA COLI; FERMENTATION; ORGANIC ACIDS; PROTEINS;

ENZYME ACTIVITY;

DOMESTIC CHEMICAL; GLYCOLATE AMMONIUM; GLYCOLIC ACID; NITRILASE; UNCLASSIFIED DRUG; ACETONITRILE DERIVATIVE; GLYCOLIC ACID DERIVATIVE; GLYCOLONITRILE; HYDROLASE; RECOMBINANT PROTEIN;

ACIDOVORAX FACILIS; ARTICLE; BACTERIUM; BIOCATALYST; CHEMOENZYMATIC PRODUCTION; ENZYME SPECIFICITY; ESCHERICHIA COLI; FERMENTATION; MUTAGENESIS; PROTEIN ENGINEERING; SYNTHESIS; BETAPROTEOBACTERIA; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; METHODOLOGY;

ACIDOVORAX FACILIS;

ACETONITRILES; AMINOHYDROLASES; BETAPROTEOBACTERIA; ESCHERICHIA COLI; GLYCOLATES; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 38449100624     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21643     Document Type: Article

References (8)

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