Ocular surface reconstruction: Recent advances and future outlook

Current Opinion in Ophthalmology

Volumn 18, Issue 6, 2007, Pages 509-514

  Yiu, Samuel C ^a,b,c   Thomas, Padmaja B ^a   Nguyen, Pho ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c DOHENY EYE INSTITUTE   (United States)

Author keywords

Amniotic membrane graft; Biotissue engineering; Implant devices; Limbal stem cell transplantation; Ocular surface disease; Regenerative medicine

Indexed keywords

ANTIMETABOLITE; CORTICOSTEROID; MITOMYCIN C; POLY(METHYL METHACRYLATE); TRANSFORMING GROWTH FACTOR BETA;

AMNION; CATARACT; CONJUNCTIVA; CORNEA; CORNEA TRANSPLANTATION; DEVICE; EXCIMER LASER; EXTRAOCULAR MUSCLE; EYE DISEASE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IMPLANT; KERATECTOMY; KERATOPROSTHESES; LACRIMAL GLAND; LIMBAL STEM CELL TRANSPLANTATION; PATHOGENESIS; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; STEM CELL; TISSUE ENGINEERING; TISSUE GRAFT; TISSUE TRANSPLANTATION; BANDAGE; BIOMEDICAL ENGINEERING; CELL FUNCTION; CONJUNCTIVA DISEASE; CORNEA DISEASE; CORNEA LIMBUS; CYTOLOGY; EYE SURGERY; LACRIMAL GLAND DISEASE; MOLECULAR BIOLOGY; PLASTIC SURGERY; RESEARCH; STEM CELL TRANSPLANTATION;

BIOLOGICAL DRESSINGS; BIOMEDICAL ENGINEERING; CELL PHYSIOLOGY; CONJUNCTIVAL DISEASES; CORNEAL DISEASES; CORNEAL TRANSPLANTATION; HUMANS; LACRIMAL APPARATUS DISEASES; LIMBUS CORNEAE; MOLECULAR BIOLOGY; OPHTHALMOLOGIC SURGICAL PROCEDURES; RECONSTRUCTIVE SURGICAL PROCEDURES; RESEARCH; STEM CELL TRANSPLANTATION; TISSUE TRANSPLANTATION;

EID: 38449091910     PISSN: 10408738     EISSN: None     Source Type: Journal    
DOI: 10.1097/ICU.0b013e3282f0ab33     Document Type: Review

References (43)

1. Selvam S, Thomas PB, Yiu SC. Tissue engineering: current and future approaches to ocular surface reconstruction. Ocul Surf 2006; 4:120-136. This paper gives a good synopsis of tissue engineering approaches for ocular surface reconstruction.
2. Selvam S, Thomas PB, Trousdale MD, et al. Tissue-engineered tear secretory system: functional lacrimal gland acinar cells cultured on matrix protein-coated substrata. J Biomed Mater Res B Appl Biomater 2007; 80:192-200.
3. Yoshino K. Establishment of a human lacrimal gland epithelial culture system with in vivo mimicry and its substrate modulation. Cornea 2000; 19:S26-S36.
4. Schechter J, Stevenson D, Chang D, et al. Growth of purified lacrimal acinar cells in Matrigel raft cultures. Exp Eye Res 2002; 74:349-360.
5. Dua HS, Gomes JA, King AJ, Maharajan VS. The amniotic membrane in ophthalmology. Surv Ophthalmol 2004; 49:51-77.
6. Cordeiro MF, Chang L, Lim KS, et al. Modulating conjunctival wound healing. Eye 2000; 14 (Pt 3B):536-547.
7. Solomon A, Espana EM, Tseng SC. Amniotic membrane transplantation for reconstruction of the conjunctival fornices. Ophthalmology 2003;110:93-100.
8. Tsubota K, Satake Y, Kaido M, et al. Treatment of severe ocular-surface disorders with corneal epithelial stem-cell transplantation. N Engl J Med 1999; 340:1697-1703.
9. Khaw PT, Chang L, Wong TT, et al. Modulation of wound healing after glaucoma surgery. Curr Opin Ophthalmol 2001; 12:143-148.
10. Andreev K, Zenkel M, Kruse F, et al. Expression of bone morphogenetic proteins (BMPs), their receptors, and activins in normal and scarred conjunctiva: role of BMP-6 and activin-A in conjunctival scarring? Exp Eye Res 2006; 83:1162-1170. This study presents new evidence of a significant role of BMP-6 and activin A growth factors in the conjunctival scarring response.
11. Rheinwald JG. Serial cultivation of normal human epidermal keratinocytes. Methods Cell Biol 1980; 21A:229-254.
12. Martin MJ, Muotri A, Gage F, Varki A. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005; 11:228-232.
13. Chen YT, Li W, Hayashida Y, et al. Human amniotic epithelial cells as novel feeder layers for promoting ex vivo expansion of limbal epithelial progenitor cells. Stem Cells 2007; 10 May [Epub ahead of print]. This paper provides an option to minimize xenobiotic issues in the cultivation and transplantation of human amniotic epithelial cells.
14. Risse Marsh BC, Massaro-Giordano M, Marshall CM, et al. Initiation and characterization of keratinocyte cultures from biopsies of normal human conjunctiva. Exp Eye Res 2002; 74:61-69.
15. Ang LP, Tan DT, Cajucom-Uy H, Beuerman RW. Autologous cultivated conjunctival transplantation for pterygium surgery. Am J Ophthalmol 2005; 139:611-619.
16. Nehls SM. Tissue adhesives for repair of corneal perforations. American Academy of Ophthalmology, Current Insight 2007; online edition. This study is important in that it provides a rapid and inexpensive means to prevent progression of corneal surface damage by various causes.
17. Kenyon KR, Tseng SC. Limbal autograft transplantation for ocular surface disorders. Ophthalmology 1989; 96:709-722.
18. Tseng SC. Significant impact of limbal epithelial stemcells. Indian J Ophthalmol 2000; 48:79-81.
19. Tsai RJ, Li LM, Chen JK. Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. N Engl J Med 2000; 343:86-93.
20. Schwab IR, Reyes M, Isseroff RR. Successful transplantation of bioengineered tissue replacements in patients with ocular surface disease. Cornea 2000; 19:421-426.
21. Rama P, Bonini S, Lambiase A, et al. Autologous fibrin-cultured limbal stem cells permanently restore the corneal surface of the patients with total limbal stem cell deficiency. Transplantation 2001; 72:1478-1485.
22. Ang LP, Sotozono C, Koizumi N, et al. A comparison between cultivated and conventional limbal stem cell transplantation for Stevens-Johnson syndrome. Am J Ophthalmol 2007; 143:178-180. This study suggests a good prognosis for patients with Stevens-Johnson syndrome with cultivated limbal stem-cell transplantation.
23. Tanioka H, Kawasaki S, Yamasaki K, et al. Establishment of a cultivated human conjunctival epithelium as an alterative tissue source for autologous corneal epithelial transplantation. Invest Ophthalmol Vis Sci 2006; 47:3820-3829.
24. Kim JC, Tseng SCG. Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea 1995; 14:473-484.
25. Azuara-Blanco A, Pillai CT, Dua HS. Amniotic membrane transplantation for ocular surface reconstruction. Br J Ophthalmol 1999; 83:399-402.
26. Gomes JA, dos Santos MS, Cunha MC, et al. Amniotic membrane transplantation for partial and total limbal stem cell deficiency secondary to chemical burn. Ophthalmology 2003; 110:466-473.
27. Nakamura T, Yoshitani M, Rigby H, et al. Sterilized, freeze-dried amniotic membrane: a useful substrate for ocular surface reconstruction. Invest Ophthalmol Vis Sci 2004; 45:93-94.
28. Higa K, Shimmura S, Kato N, et al. Proliferation and differentiation of transplantable rabbit epithelial sheets engineered with or without an amniotic membrane carrier. Invest Ophthalmol Visual Sci 2007; 48:597-615. This study describes an effective method to study tissue engineering with a commercially available fibrin sealant to produce a transplantable corneal epithelial sheet.
29. Homma R, Yoshikawa H, Takeno M, et al. Induction of epithelial progenitors in vitro from mouse embryonic stem cells and application for reconstruction of damaged cornea in mice. Invest Ophthalmol Vis Sci 2004; 45:4320-4326.
30. Ma Y, Xu Y, Xiao Z, et al. Reconstruction of chemically burned rat corneal surface by bone marrow-derived human mesenchymal stem cells. Stem Cells 2006; 24:315-321. This study suggests that readily retrievable bone marrow mesenchymal stem cells may be a viable solution to limbal stem cell depletion in ocular surface reconstruction. The shortage of stem cells and allograft rejection will be circumvented.
31. Nakamura T, Inatomi T, Sotozono C, et al. Transplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders. Br J Ophthalmol 2004; 88:1280-1284.
32. Nishida K, Yamato M, Hayashida Y, et al. Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. N Engl J Med 2004; 351:1187-1196.
33. Ang L, Nakamura T, Inatomi T, et al. Autologous serum-derived cultivated oral epithelial transplants for severe ocular surface disease. Arch Ophthalmol 2006; 124:1543-1551. Successful transplantation of autologous serum-derived cultivated oral epithelium is significant in many aspects: reduction of xenobiotic materials in the transplant, decreasing risk of infection transmission, minimizing risk of allograft immunologic rejection, and reducing the need for immunosuppressive therapy.
34. Barker NH, Henderson TR, Ross CA, et al. Current Australian practice in the prevention and management of corneal allograft rejection. Clin Exp Ophthalmol 2000; 28:357-360.
35. Randleman JB, Stulting RD. Prevention and treatment of corneal graft rejection: current practice patterns. Cornea 2006; 25:286-290.
36. Nguyen P, Yiu SC. Multi-agent pharmaceutical therapy for modulation of corneal allograft immunologic rejection. American Academy of Ophthalmology, Current Insight 2007; online edition (in press).
37. Doane MG, Dohlman CH, Bearse G. Fabrication of a keratoprosthesis. Cornea 1996; 15:179-184.
38. Myung D, Koh W, Bakri A, et al. Design and fabrication of an artificial cornea based on a photolithographically patterned hydrogel construct. Biomed Microdevices, 2007; 20 Jan [Epub ahead of print].
39. Hayashida Y, Nishida K, Yamato M, et al. Transplantation of tissue-engineered epithelial cells sheets after excimer laser photoablation reduces postoperative corneal haze. Invest Ophthalmol Vis Sci 2006; 47:552-557. This study presents an application of corneal epithelial cell transplantation to minimize the inflammatory cascade and prevent corneal haze after excimer keratectomy.
40. Holland G. The first eye operation: cataract surgery. Milestones Innovation 17, 2006. Carl Zeiss (in-house publication).
41. Ridley NHL. Intraocular acrylic lenses. Trans Ophthalmol Soc UK 1951; 71:617-621.
42. Ridley NHL. Intraocular acrylic lenses: a recent development in the surgery of cataract. Br J Ophthalmol 1952; 36:113-122.
43. Kelman CD. Phacoemulsification and aspiration: a new technique of cataract extraction. Am J Ophthalmol 1967; 64:23-35.