Prolongation of survival of fully allogeneic cardiac grafts and generation of regulatory cells by a histamine receptor 2 antagonist

Transplantation

Volumn 84, Issue 10, 2007, Pages 1288-1297

  Inoue, Fumihiko ^a   Zhang, Qi ^b   Akiyoshi, Takurin ^a   Aramaki, Osamu ^b,c   Iwami, Daiki ^b   Matsumoto, Kenji ^a   Kitagawa, Yuko ^a   Shirasugi, Nozomu ^b   Niimi, Masanori ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

^c NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cardiac transplantation; Mouse; Ranitidine; Regulatory cells

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 2; RANITIDINE; TACROLIMUS; CYTOKINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR;

ADOPTIVE TRANSFER; ALLOIMMUNITY; ALLOTRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 10 MOUSE; CARDIAC GRAFT REJECTION; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DOSE COMPARISON; ENZYME LINKED IMMUNOSORBENT ASSAY; GRAFT RECIPIENT; GRAFT SURVIVAL; HEART GRAFT; HEART TRANSPLANTATION; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; LOW DRUG DOSE; MALE; MIXED LEUKOCYTE CULTURE; MONOTHERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SINGLE DRUG DOSE; SPLEEN CELL; SURVIVAL TIME; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; CBA MOUSE; DRUG EFFECT; IMMUNOLOGY; ISOGRAFT; PHYSIOLOGY;

ADOPTIVE TRANSFER; ANIMALS; CYTOKINES; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTAMINE H1 ANTAGONISTS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED CBA; RANITIDINE; RECEPTORS, HISTAMINE; TRANSPLANTATION, HOMOLOGOUS; TRANSPLANTATION, ISOGENEIC;

EID: 38449086262     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000287641.69795.cc     Document Type: Article

References (37)

1. Perry NL, Zola H, Nicholson IC. Histamine receptors on T lymphocytes. J Biol Regul Homeost Agents 2005; 19: 78.
2. Jutel M, Watanabe T, Klunker S, et al. Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature 2001; 413: 420.
3. Kunzmann S, Mantel PY, Wohlfahrt JG, Akdis M, Blaser K, Schmidt-Weber CB. Histamine enhances TGF-beta1-mediated suppression of Th2 responses. FASEB J 2003; 17: 1089.
4. van der Pouw Kraan TC, Snijders A, Boeije LC, et al. Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest 1998; 102: 1866.
5. Itoh H, Takahashi HK, Iwagaki H, et al. Effect of histamine on intercellular adhesion molecule-1 expression and production of interferongamma and interleukin-12 in mixed lymphocyte reaction stimulated with interleukin-18. Transplantation 2002; 74: 864.
6. Teuscher C, Poynter ME, Offner H, et al. Attenuation of Th1 effector cell responses and susceptibility to experimental allergic encephalomyelitis in histamine H2 receptor knockout mice is due to dysregulation of cytokine production by antigen-presenting cells. Am J Pathol 2004; 164: 883.
7. Kohka H, Nishibori M, Iwagaki H, et al. Histamine is a potent inducer of IL-18 and IFN-gamma in human peripheral blood mononuclear cells. J Immunol 2000; 164: 6640.
8. Xu X, Zhang D, Zhang H, et al. Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. J Exp Med 2006; 203: 2907.
9. Moore TC, Chang JK. Urinary histamine excretion in the rat following skin homografting and autografting. Ann Surg 1967; 167: 232.
10. Dy M, Lebel B, Kamoun P, Hamburger J. Histamine production during the anti-allograft response. Demonstration of a new lymphokine enhancing histamine synthesis. J Exp Med 1981; 153: 293.
11. Minami M, Nakahara K, Matsumura A, et al. Histamine release from pulmonary mast cells after lung transplantation in rats. J Heart Lung Transplant 1995; 14: 505.
12. Li QY, Raza-Ahmad A, MacAulay MA, et al. The relationship of mast cells and their secreted products to the volume of fibrosis in posttransplant hearts. Transplantation 1992; 53: 1047.
13. Olausson M, Wramner L, Blohme I, Mjornstedt L. Heart allograft rejection in rats triggered by H2 inhibitors. Transplant Proc 1997; 29: 3127.
14. Benoit G, Moukarzel M, Verdelli G, et al. Gastrointestinal complications in renal transplantation. Transpl Int 1993; 6: 45.
15. Niimi M. The technique for heterotopic cardiac transplantation in mice: Experience of 3000 operations by one surgeon. J Heart Lung Transplant 2001; 20: 1123.
16. Shibutani S, Inoue F, Aramaki O, et al. Effects of immunosuppressants on induction of regulatory cells after intratracheal delivery of alloantigen. Transplantation 2005; 79: 904.
17. Akiyama Y, Shirasugi N, Uchida N, et al. B7/CTLA4 pathway is essential for generating regulatory cells after intratracheal delivery of alloantigen in mice. Transplantation 2002; 74: 732.
18. Perros P, Weightman DR. Measurement of cell proliferation by enzyme-linked immunosorbent assay (ELISA) using a monoclonal antibody to bromodeoxyuridine. Cell Prolif 1991; 24: 517.
19. Tanaka H, Sukhova GK, Swanson SJ, Cybulsky MI, Schoen FJ, Libby P. Endothelial and smooth muscle cells express leukocyte adhesion molecules heterogeneously during acute rejection of rabbit cardiac allografts. Am J Pathol 1994; 144: 938.
20. Lee JR, Huh JH, Seo JW, Suk CJ, Jeong HM, Kim EK. Time-dependent expression of ICAM-1 & VCAM-1 on coronaries of the heterotopically transplanted mouse heart. J Korean Med Sci 1999; 14: 245.
21. Briscoe DM, Yeung AC, Schoen FJ, et al. Predictive value of inducible endothelial cell adhesion molecule expression for acute rejection of human cardiac allografts. Transplantation 1995; 59: 204.
22. Wood KJ, Sakaguchi S. Regulatory T cells in transplantation tolerance. Nat Rev Immunol 2003; 3: 199.
23. Wan YY, Flavell RA. The roles for cytokines in the generation and maintenance of regulatory T cells. Immunol Rev 2006; 212: 114.
24. Aramaki O, Inoue F, Takayama T, et al. Interleukin-10 but not transforming growth factor-beta is essential for generation and suppressor function of regulatory cells induced by intratracheal delivery of alloantigen. Transplantation 2005; 79: 568.
25. Roncarolo MG, Gregori S, Battaglia M, Bacchetta R, Fleischhauer K, Levings MK. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 2006; 212: 28.
26. Caron G, Delneste Y, Roelandts E, et al. Histamine induces CD86 expression and chemokine production by human immature dendritic cells. J Immunol 2001; 166: 6000.
27. Delneste Y, Lassalle P, Jeannin P, Joseph M, Tonnel AB, Gosset P. Histamine induces IL-6 production by human endothelial cells. Clin Exp Immunol 1994; 98: 344.
28. Stepkowski SM, Wang ME, Condon TP, et al. Protection against allograft rejection with intercellular adhesion molecule-1 antisense oligodeoxynucleotides. Transplantation 1998; 66: 699.
29. Lacha J, Bushell A, Smetana K, et al. Intercellular cell adhesion molecule-1 and selectin ligands in acute cardiac allograft rejection: A study on gene-deficient mouse models. J Leukoc Biol 2002; 71: 311.
30. Labarrere CA, Nelson DR, Park JW. Pathologic markers of allograft arteriopathy: Insight into the pathophysiology of cardiac allograft chronic rejection. Curr Opin Cardiol 2001; 16: 110.
31. Akdis CA, Blaser K. Histamine in the immune regulation of allergic inflammation. J Allergy Clin Immunol 2003; 112: 15.
32. Gantner F, Sakai K, Tusche MW, Cruikshank WW, Center DM, Bacon KB. Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells. J Pharmacol Exp Ther 2002; 303: 300.
33. Conti P, Kempuraj D, Kandere K, et al. Interleukin-16 network in inflammation and allergy. Allergy Asthma Proc 2002; 23: 103.
34. Auchincloss H Jr. In search of the elusive Holy Grail: The mechanisms and prospects for achieving clinical transplantation tolerance. Am J Transplant 2001; 1: 6.
35. Rendic S, Di Carlo FJ. Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers, and inhibitors. Drug Metab Rev 1997; 29: 413.
36. Fleming I. Cytochrome p450 and vascular homeostasis. Circ Res 2001; 89: 753.
37. Festen HP, Berden JH, Koene RA. Cimetidine does not accelerate skin graft rejection in mice. Clin Exp Immunol 1980; 40: 193.