Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy;Respuesta a la idebenona asociada a multivitaminoterapia en neuropatía óptica hereditaria de Leber

Archivos de la Sociedad Espanola de Oftalmologia

Volumn 82, Issue 6, 2007, Pages 377-380

  Barnils García, Noemí ^a   Mesa, E ^a   Munoz S ^a   Ferrer Artola, A ^a   Arruga, J ^a  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Hereditary neuropathy; Idebenone; Leber's hereditary optic neuropathy; Multivitamins

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BENZOQUINONE DERIVATIVE; IDEBENONE; RIBOFLAVIN; VITAMIN; VITAMIN B COMPLEX;

ADULT; ARTICLE; CASE REPORT; FEMALE; HUMAN; LEBER HEREDITARY OPTIC NEUROPATHY; MALE; TREATMENT FAILURE;

ADULT; ANTIOXIDANTS; ASCORBIC ACID; BENZOQUINONES; FEMALE; HUMANS; MALE; OPTIC ATROPHY, HEREDITARY, LEBER; RIBOFLAVIN; TREATMENT FAILURE; VITAMIN B COMPLEX; VITAMINS;

EID: 38449084377     PISSN: 03656691     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Sánchez Dalmau B. Nunes V. Neuropatías ópticas heredodegenerativas. En: Arruga Ginebreda J. Sánchez Dalmau B. Neuropatías ópticas: diagnóstico y tratamiento. LXXVIII Ponencia oficial de la SEO. Madrid: Mac Line 2002; 143-147.
2. Cortelli P, Montagna P, Pierangeli G, Lodi R, Barboni P, Liguori R, et al. Clinical and brain bionergetics improvement with idebenone in a patient with Leber's hereditary optic neuropathy: a clinical and 31P-MRS study. J Neurol Sci 1997; 148: 25-31.
3. Mashima Y, Hiida Y, Oguchi Y. Remission of Leber's hereditary optic neuropathy with idebenone. Lancet 1992; 340: 368-369.
4. Carelli V, Barboni P, Zacchini A, Mancini R, Monari L, Cevoli S, et al. Leber's Hereditary Optic Neuropathy (LHON) with 14484/ND6 mutation in a North African patient. J Neurol Sci 1998; 160: 183-188.
5. Mashima Y, Kigasawa K, Wakakura M, Oguchi Y. Do idebenone and vitamin therapy shorten the time to achieve visual recovery in Leber hereditary optic neuropathy? J Neuroophthalmoly 2000; 20: 166-170.