Clinical and brain bioenergetics improvement wiuth idebenone in a patient with Leber's hereditary optic neuropathy: A clinical and 31P-MRS study

Journal of the Neurological Sciences

Volumn 148, Issue 1, 1997, Pages 25-31

  Cortelli, Pietro ^a,c   Montagna, Pasquale ^a   Pierangeli, Giulia ^a   Lodi, Raffaele ^a   Barboni, Piero ^a   Liguori, Rocco ^a   Carelli, Valerio ^a   Iotti, Stefano ^a   Zaniol, Paolo ^b   Lugaresi, Elio ^a   Barbiroli, Bruno ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c Clinica Neurologica   (Italy)

Author keywords

31 phosphorus magnetic resonance spectroscopy (31 P MRS); idebenone; Leber's hereditary optic neuropathy; mitochondrion; paraparesis

Indexed keywords

IDEBENONE;

ADULT; ARTICLE; BIOENERGY; BRAIN REGION; CASE REPORT; CLINICAL TRIAL; CROSSOVER PROCEDURE; HEREDITARY OPTIC ATROPHY; HUMAN; MALE; MUSCLE; MUTATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORAL DRUG ADMINISTRATION; PARAPLEGIA; PRIORITY JOURNAL;

ADULT; BENZOQUINONES; BRAIN; ENERGY METABOLISM; FOLLOW-UP STUDIES; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; NEUROLOGIC EXAMINATION; OPTIC ATROPHIES, HEREDITARY; PARAPARESIS, TROPICAL SPASTIC; PHOSPHORUS ISOTOPES;

EID: 0031148560     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(96)00311-5     Document Type: Article

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