Anti-aging medicine: Hormone replacement therapy in men

Plastic and Reconstructive Surgery

Volumn 113, Issue 5, 2004, Pages 1506-1510

  Kaweski, Susan ^a,b  

^a Craniofac Reconstr/Cosmet Inst ^*

^b Craniofac Reconstr/Cosmet Inst   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEL TESTIM; ANTIDEPRESSANT AGENT; BETA CYCLODEXTRIN; MICROSPHERE; PRASTERONE; TESTOSTERONE; TESTOSTERONE CIPIONATE; TESTOSTERONE DERIVATIVE; TESTOSTERONE ENANTATE; TESTOSTERONE HYDROXYPROPYL BETA CYCLODEXTRIN; TESTOSTERONE UNDECANOATE; UNCLASSIFIED DRUG; ANDROGEN;

AGING; ANDROGEN DEFICIENCY; ANDROPAUSE; ARTICLE; BITTER TASTE; CLINICAL TRIAL; DERMATITIS; DRUG CONTRAINDICATION; DRUG EFFECT; DRUG PELLET; ELECTROLYTE DISTURBANCE; FOLLOW UP; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; HYPOGONADISM; LONGEVITY; MALE; MUSCLE FUNCTION; PRIORITY JOURNAL; PRURITUS; SKIN IRRITATION; SODIUM RETENTION; TASTE DISORDER; TESTOSTERONE BLOOD LEVEL; OSTEOPOROSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; SEXUAL BEHAVIOR;

AGING; ANDROGENS; HORMONE REPLACEMENT THERAPY; HUMANS; MALE; OSTEOPOROSIS; SEXUAL BEHAVIOR; TESTOSTERONE;

EID: 3843151828     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PRS.0000125283.18798.DA     Document Type: Article

References (58)

1. Comhaire, F. H. Andropause: Hormone replacement therapy in the ageing male. Eur. Urol. 38: 655, 2000.
2. Vermeulen, A. Andropause. Maturitas 34: 5, 2000.
3. Anderson, J. K., Faulkner, S., Cranor, C., Briley, J., Gevirtz, F., and Roberts, S. Andropause: Knowledge and perceptions among the general public and health care professionals. J. Gerontol. A. Biol. Sci. Med. Sci. 57: M793, 2002.
4. Morales, A., Heaton, J. P. W., and Carson, C. C. Andropause: A misnomer for a true clinical entity. J. Urol. 163: 705, 2000.
5. Morales, A. Androgen replacement therapy and prostate safety. Eur. Urol. 41: 113, 2002.
6. Hermann, M., and Berger, P. Aging of the male endocrine system. Rev. Physiol. Biochem. Pharmacol. 139: 89, 1999.
7. Juul, A., and Skakkebaek, N. E. Androgens and the ageing male. Hum. Reprod. Update 8: 423, 2002.
8. Matsumoto, A. M. Andropause: Clinical implications of the decline in serum testosterone levels with aging in men. J. Gerontol. A. Biol. Sci, Med. Sci. 57: M76, 2002.
9. Anawalt, B. D., and Merriam, G. R. Neuroendocrine aging in men: Andropause and somatopause. Endocrinol. Metab. Clin. North Am. 30: 647, 2001.
10. Haren, M. T., Morley, J. E., Chapman, I. M., O'Loughlin, P. D., and Wittert, G. A. Defining "relative" androgen deficiency in aging men: How should testosterone be measured and what are the relationships between androgen levels and physical, sexual and emotional health? Climacteric 5: 15, 2002.
11. Morales, A., and Tenover, J. L. Androgen deficiency in the aging male: When, who, and how to investigate and treat. Urol. Clin. North Am. 29: 975, 2002.
12. Wu, C. Y., Yu, T. J., and Chen, M. J. Age related testosterone level changes and male andropause syndrome. Chang Gung Med. J. 23: 348, 2000.
13. Tenover, J. L. Testosterone replacement therapy in older adult men. Int. J. Androl. 22: 300, 1999.
14. Janssens, H., and Vanderschueren, D. M. Endocrinological aspects of aging in men: Is hormone replacement of benefit? Eur. J. Obstet. Gynecol. Reprod. Biol. 92: 7, 2000.
15. Morley, J. E., and Perry, H. M., III. Androgen deficiency in aging men: Role of testosterone replacement therapy. J. Lab. Clin. Med. 135: 370, 2000.
16. Lund, B. C., Bever-Stille, K. A., and Perry, P. J. Testosterone and andropause: The feasibility of testosterone replacement therapy in elderly men. Pharmacotherapy 19: 951, 1999.
17. Heaton, J. P. Point: Urologists should take an active role in the diagnosis and treatment of hypogonadism in the aging male. Can. J. Urol. 9: 1677, 2002.
18. Nolten, W. E. Androgen deficiency in the aging male: When to evaluate and when to treat. Curr. Urol. Rep. 1: 313, 2000.
19. Vermeulen, A. Androgen replacement therapy in the aging male: A critical evaluation. J. Clin. Endocrinol. Metab. 86: 2380, 2001.
20. Gambineri, A., Pelusi, C., Vicennati, V., Pagotto, U., and Pasquali, R. Testosterone in ageing men. Expert Opin. Investig. Drugs 10: 477, 2001.
21. Kim, Y. C. Testosterone supplementation in the aging male. Int. J. Impot. Res. 11: 343, 1999.
22. Heaton, J. P., and Morales, A. Andropause: A multisystem disease. Can. J. Urol. 8: 1213, 2001.
23. Howell, S., and Shalet, S. Testosterone deficiency and replacement. Horm. Res. 56 (Suppl. 1): 86, 2001.
24. Bonney, R. C. Hormone replacement therapy for men. Am. Clin. Lab. 16: 3, 1997.
25. Velazquez, E., and Bellabarba Arata, G. Testosterone replacement therapy. Arch. Androl. 41: 79, 1998.
26. Cutter, C. B. Compounded percutaneous testosterone gel: Use and effects in hypogonadal men. J. Am. Board Fam. Pract. 14: 22, 2001.
27. Rolf, C., Kemper, S., Lemmnitz, G., Eickenberg, U., and Nieschlag, E. Pharmacokinetics of a new transdermal testosterone gel in gonadotrophin- suppressed normal men. Eur. J. Endocrinol. 146: 673, 2002.
28. Mazer, N. A. New clinical applications of transdermal testosterone delivery in men and women. J. Control. Release 65: 303, 2000.
29. Advisory Panel on Testosterone Replacement in Men. Report of National Institute on Aging Advisory Panel on Testosterone Replacement in Men. J. Clin. Endocrinol. Metab. 86: 4611, 2001.
30. Hoffman, A. R. Should we treat the andropause? Am. J. Med. 111: 322, 2001.
31. Wespes, E., and Schulman, C. C. Male andropause: Myth, reality, and treatment. Int. J. Impot. Res. 14 (Suppl. 1): S93, 2002.
32. Slater, S., and Oliver, R. T. Testosterone: Its role in development of prostate cancer and potential risk from use as hormone replacement therapy. Drugs Aging 17: 431, 2000.
33. Tenover, J. L. Experience with testosterone replacement in the elderly. Mayo Clin Proc. 75 (Suppl): S77; discussion S82, 2000.
34. Conway, A.J., Handelsman, D.J., Lording, D. W., Stuckey, B., and Zajax, J. D. Use, misuse and abuse of androgen: The Endocrine Society of Australia consensus guidelines for androgen prescribing. Med. J. Aust. 172: 220, 2000.
35. Tan, R. S., and Culberson, J. W. An integrative review on current evidence of testosterone replacement therapy for the andropause. Maturitas 45: 15, 2003.
36. Viallard, J. F., Marit, G., Mercie, P., Leng, B., Reiffers, J., and Pellegrin, J. L. Polycythaemia as a complication of transdermal testosterone therapy. Br. J. Haematol. 110: 237, 2000.
37. Bhasin, S., and Buckwalter, J. G. Testosterone supplementation in older men: A rational idea whose time has not yet come. J. Andol. 22: 718, 2001.
38. Nehra, A. Treatment of endocrinologic male sexual dysfunction. Mayo Clin Proc. 75 (Suppl.): S40, 2000.
39. Morley, J. E. Androgens and aging. Maturitas 38: 61, 2001.
40. Webb, C. M., Adamson, D. L., de Zeigler, D., and Collins, P. Effect of acute testosterone on myocardial ischemia in men with coronary artery disease. Am. J. Cardiol. 83: 437, 1999.
41. English, K. M., Steeds, R. P., Jones, T. H., Diver, M.J., and Channer, K. S. Low dose transdermal testosterone therapy improves angina threshold in men with chronic stable angina: A randomized, double-blind, placebo-controlled study. Circulation 102: 1906, 2000.
42. Rosano, G. M., Leonardo, F., Pagnotta, P., et al. Acute anti-ischemic effect of testosterone in men with coronary artery disease. Circulation 99: 1666, 1999.
43. Carani, C., Zini, D., Baldini, A., Della Casa, L., Ghizzani, A., and Marrama, P. Effects of androgen treatment in impotent men with normal and low levels of free testosterone. Arch. Sex Behav. 19: 223, 1990.
44. Buena, F., Swerdloff, R. S., Steiner, B. S., et al. Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range. Fertil. Steril. 59: 1118, 1993.
45. Sternbach, H. Age-associated testosterone decline in men: Clinical issues for psychiatry. Am. J. Psychiatry 155: 1310, 1998.
46. Schiavi, R. C. Androgens and sexual function in men. In B. J. Oddens and A. Vermeulen (Eds.): Androgens and AgingMale. London: Parthenon Publishing, 1996. Pp. 111-125.
47. Novak, A., Brod, M., and Elbers, J. Andropause and quality of life: Findings from patient focus groups and clinical experts. Maturitas 43: 231, 2002.
48. Margolese, H. C. The male menopause and mood: Testosterone decline and depression in the aging male - Is there a link? J. Geriatr. Psychiatry Neurol. 13: 93, 2000.
49. Seidman, S. N. Testosterone deficiency and mood in aging men: Pathogenic and therapeutic implications. World J. Biol. Psychiatry 4: 14, 2003.
50. Sih, R., Morley, J. E., Kaiser, F. E., Perry, H. M., III, Patrick, P., and Ross, C. Testosterone replacement in older hypogonadal men: A 12 month randomized controlled trial. J. Clin. Endocrinol. Metab. 82: 1661, 1997.
51. Schiavi, R. C., White, D., Mandeli, J., and Levine, A. C. Effect of testosterone administration on sexual behavior and mood in men with erectile dysfunction. Arch. Sex Behav. 26: 231, 1997.
52. Kenny, A. M., Bellantonio, S., Gruman, C. A., Acosta, R. D., Prestwood, K. M. Effects of transdermal testosterone on cognitive function and health perception in older men with low bioavailable testosterone levels. J. Gerontol. A. Biol. Sci. Med. Sci. 57: M321, 2002.
53. Francis, R. M. Androgen replacement in aging men. Calcif. Tissue Int. 69: 235, 2001.
54. Francis, R. M. The effects of testosterone on osteoporosis in men. Clin. Endocrinol. (Oxf.) 50: 411, 1999.
55. Kenny, A. M., Prestwood, K. M., Gruman, C. A., Marcello, K. M., and Raisz, L. G. Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels. J. Gerontol. A. Biol. Sci. Med. Sci. 56: M266, 2001.
56. Snyder, P.J., Peachey, H., Hannoush, P., et al. Effect of testosterone treatment on bone mineral density in men over 65 years of age. J. Clin. Endocrinol. Metab. 84: 1966, 1999.
57. Katznelson, L., Finkelstein, J. S., Schoenfeld, D. A., Rosenthal, D. I., Anderson, E. J., and Klibanski, A. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J. Clin. Endocrinol. Metab. 81: 4358, 1996.
58. Tenover, J. S. Androgen replacement therapy to reverse and/or prevent age-associated sarcopenia in men. Baillieres Clin. Endocrinol. Metab. 12: 419, 1998.