Intranasal immunization with outer membrane protein P6 and cholera toxin induces specific sinus mucosal immunity and enhances sinus clearance of nontypeable Haemophilus influenzae

Vaccine

Volumn 22, Issue 23-24, 2004, Pages 3112-3121

  Sabirov, Albert ^a,b   Kodama, Satoru ^a   Sabirova, Nailya ^a   Mogi, Goro ^a   Suzuki, Masashi ^a  

^a OITA UNIVERSITY   (Japan)

^b KAZAN STATE MEDICAL UNIVERSITY   (Russian Federation)

Author keywords

antibody producing cells; APCs; cholera toxin; CMIS; common mucosal immune system; CT; Intranasal immunization; MNCs; mononuclear cells; NALT; nasal mucosa; nasal associated lymphoid tissue; NM; nontypeable Haemophilus influenzae; NTHi; sinus mucosa; SM

Indexed keywords

CHOLERA TOXIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN P6; UNCLASSIFIED DRUG; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; HAEMOPHILUS INFLUENZAE; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; MALE; MAXILLARY SINUS; MUCOSA; NONHUMAN; PARANASAL SINUS; PRIORITY JOURNAL; PROTECTION; RAT;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY SPECIFICITY; ANTIBODY-PRODUCING CELLS; BACTERIAL OUTER MEMBRANE PROTEINS; CHOLERA TOXIN; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS VACCINES; HISTOCYTOCHEMISTRY; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MALE; MAXILLARY SINUS; MONOCYTES; PARANASAL SINUSES; RATS; RATS, WISTAR;

EID: 3843143990     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.01.066     Document Type: Article

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