Development of antibody-secreting cells and antigen-specific T cells in cervical lymph nodes after intranasal immunization

Infection and Immunity

Volumn 65, Issue 1, 1997, Pages 227-235

  Wu, Hong Yin ^a   Nikolova, Elena B ^a,b   Beagley, Kenneth W ^a,c   Eldridge, John H ^a,d   Russell, Michael W ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b Institute of Experimental Morphology and Anthropology Bulgarian Academy of Sciences   (Bulgaria)

^c UNIVERSITY OF NEWCASTLE   (Australia)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHOLERA TOXIN B SUBUNIT; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERLEUKIN 4;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE ACTIVATION; CHOLERA; HOST RESISTANCE; INFECTION RESISTANCE; INTRANASAL DRUG ADMINISTRATION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0031022487     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.1.227-235.1997     Document Type: Article

References (46)

1. Beagley, K. W., J. H, Eldridge, H. Kiyono, M. P. Everson, W. J. Koopman, T. Honjo, and J. R. McGhee. 1988. Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells. J. Immunol. 141:2035-2042.
2. Biewenga, J., D. M. H. Hameleers, P. J. Koornstra, and C. F. Kuper. 1991. Immuno- and enzyme-histochemical and functional studies on nasal associated lymphoid tissue (NALT) in the rat. p. 603. In M. Tsuchiyam H. Nagura, T. Hibi, and I. Moro (ed.). Frontiers of mucosal immunology, vol. 2. Excerpta Medica, Amsterdam, The Netherlands.
3. Bolduc, C., J. D. Waterfield, and N. Deslauriers. 1990. Tissue distribution and cytofluorometric analysis of oral mucosal T cells in the BALB/c mouse. Res. Immunol, 141:461-175.
4. Bourguin, I., T. Chardès, and D. Bout. 1993. Oral immunization with Toxoplasma gondii antigens in association with cholera toxin induces enhanced protective and cell-mediated immunity in C57BL/6 mice. Infect. Immun. 61:2082-2088.
5. Brandtzaeg, P., and T. S. Halstensen. 1992. Immunology and immunopathology of tonsils. Adv. Otorhinolaryngol. 47:64-75.
6. Cherwinski, H. M., J. H. Sehumacher, K. D. Brown, and T. R. Mosmann. 1987. Two types ot mouse helper T cell clone III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J. Exp. Med. 166:1229-1244.
7. Clarke, C. J., A. D. Wilson, N. A. Williams, and C. R. Stokes. 1991 Mucosal priming of T-lymphocyte responses to fed protein antigens using cholera toxin as an adjuvant. Immunology 72:323-328.
8. Czerkinsky, C., M. W. Russell, N. Lycke, M. Lindblad, and J. Holmgren. 1989. Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Infect. Immun. 57:1072-1077.
9. Duncan, D. D., and S. L. Swain. 1994. Role of antigen-presenting cells in the polarized development of helper T cell subsets: evidence for differential cytokine production by Th0 cells in response to antigen presentation by B cells and macrophages. Eur. J. Immunol. 24:2506-2514.
10. Elson, C. O. 1989. Cholera toxin and its subunits as potential oral adjuvants. Curr. Top. Microbiol. Immunol. 146:29-33.
11. Gizurarson, S., S. Tamura, T. Kurata, K. Hasiguchi, and H. Ogawa. 1991. The effect of cholera toxin and cholera toxin B subunit on the nasal mucosa membrane. Vaccine 9:825-832.
12. Hajishengallis, G., S. M. Michalek, and M. W. Russell. 1996. Persistence of serum and salivary antibody responses after oral immunization with a bacterial protein antigen genetically linked to the A2/B subunits of cholera toxin. Infect. Immun. 64:665-667.
13. Hameleers, D. M. H., I. van der Ven, J. Biewenga, and T. Sminia. 1991. Mucosal and systemic antibody formation in the rat after intranasal administration of three different antigens. Immunol. Cell Biol. 69:119-125.
14. Hameleers, D. M. H., I. van der Ven, T. Sminia, and J. Biewenga. 1990. Anti-TNP forming cells in rats after different routes of priming with TNP-LPS followed by intranasal boosting with the same antigen. Res. Immunol. 141:515-528.
15. Hazama, M., A. Mayumi-Aono, T. Miyazaki, S. Hinuma, and Y. Fujisawa. 1993. Intranasal immunization against herpes simplex virus infection by using a recombinant glycoprotein D fused with immunomoduluting proteins. the B subunit of Escherichia colt heat-labile enterotoxin and interleukin-2. Immunology 78:643-649.
16. Heinzel, F. P., M. D. Sadick, B. J. Holaday, R. L. Coffman, and R. M. Locksley. 1988. Reciprocal expression of interferon-γ or interleukin-4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subunits. J. Exp Med. 169:59-72.
17. Hu-Li, J., J. Ohara, C. Watson, W. Tsang, and W. E. Paul. 1989 Derivation of a T cell line that is highly responsive to IL-4 and IL-2 (CT.4R) and of an IL-2 hyporesponsive mutant of that line (CT.4S). J. Immunol. 142:800-807.
18. Kikuta, K., Y. Hirabayashi, T. Nagamine, C. Aizawa, Y. Ueno, A. Oya, T. kurata, and S.-I. Tamura. 1990. Cross-protection against influenza B type virus infection by intranasal inoculation of the HA vaccines combined with cholera toxin B subunit. Vaccine 8:595-599.
19. Koornstra, P. J., F. I. C. R. S. De Jong, L. F. M. Vlek, E. H. M. A. Marres, and P. J. C. van Breda Vriesman. 1991. The Waldeyer ring equivalent in the rat. A model for analysis of oronasopharyngeal immune responses. Acta Otolaryngol. 111:591-599.
20. Kuper, C. F., P. J. Koornstra, D. M. H. Hameleers, J. Biewenga, B. J. Spit, A. M. Duijvestijn, P. J. C. van Breda Vriesman, and T. Sminia. 1992. The role of nasopharyngeal lymphoid tissue, Immunol. Today 13:219-224.
21. Liang, X., M. E. Lamm, and J. G. Nedrud. 1989. Cholera toxin as a mucosal adjuvant. Glutaraldehyde treatment dissociates adjuvanticity from toxicity. J. Immunol. 143:484-490.
22. Lycke, N., and J. Holmgren. 1986. Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology 59:301-308.
23. Mestecky, J. 1987. The common mucosal immune system and current strategies for induction of immune response in external secretions. J. Clin. lmmunol. 7:265-276.
24. Moldoveanu, Z., M. L. Clements, S. J. Prince, B. R. Murphy, and J. Mestecky. 1995. Human immune responses to influenza virus vaccines administered by systemic or mucosal routes. Vaccine 13:1006-1012.
25. Mosmann, T. R. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and eytotoxic assays. J. Immunol. Methods 65:55-03.
26. Mosmann, T. R., and R. L. Coffman. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
27. Nair, P. N. K., and K. Kossinsky. 1985. Organization of lymphoid tissue in the tonsilla lingualis. An ultrastructural study in Macaca fascicularis (Primates, Cercopithecoidea). Cell Tissue Res. 240:233-242.
28. Nair, P. N. R., and H. E. Schroeder. 1986. Duct-associated lymphoid tissue (DALT) of minor salivary glands and mucosal immunity. Immunology 57: 171-180.
29. Ogra, P. L. 1971. Effect of tonsillectonry and adenoidectomy on nasopharyngeal antibody response to poliovirus. N. Engl. J. Med. 284:59-64.
30. Quiding, M., M. Lakew, G. Granström, I. Nordström, J. Holmgren, and C. Czerkinsky. 1995. Induction of specific antibody responses in the human nasopharyngeal mucosa. Adv. Exp. Med. Biol. 371:1445-1450.
31. Reynolds, D. S., W. H. Boom, and A. K. Abbas. 1987. Inhibition of B lymphocyte activation by interferon-gamma. J. Immunol. 139:767-773.
32. Russell, M. W., L. A. Bergmeier, E. D. Zanders, and T. Lehner. 1980. Protein antigens of Streptococcus mutans: purification and properties of a double antigen and its protease-resistant component. Infect, Immun. 28:486-493.
33. Russell, M. W., and H.-Y. Wu. 1991. Distribution, persistence, and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit. Infect. Immun. 59:4061-4070.
34. Russell, M. W., H.-Y. Wu, P. L. White, I. Takahashi, N. Okahashi, and T. Koga. 1992. Peroral immunization with a cholera toxin-linked bacterial protein antigen and synthetic peptide, p. 199-207. In J. E. Ciardi, J. R. McGhee, and J. Keith (ed.). Genetically engineered vaccines: prospects for oral disease prevention. Plenum Publishing Corp., New York, N.Y.
35. Scadding, G. K. 1990. Immunology of the tonsil: a review. J. R. Soc. Med. 83:104-107.
36. Schumacher, J. H., A. O'Garra, B. Shrader, A. van kinnenade, M. W. Bond, T. R. Mosmann, and R. L. Coffman. 1988. The characterization of tour monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent assays. J. Immunol. 141: 1576-1581.
37. Snider, D. P., J. S. Marshall, M. H. Perdue, and H. Liang. 1994. Production of IgE antibody and allergic sensitization of intestinal and peripheral tissues after oral immunization with protein Ag and cholera toxin. J. Immunol. 153:647-657.
38. Spit, B. J., E. G. J. Hendriksen, J. P. Bruijntjes, and C. F. Kuper. 1989. Nasal lymphoid tissue in the rat. Cell Tissue Res. 255:193-198.
39. Takahashi, I., N. Okahashi, T. Kanamoto, H. Asakawa, and T. Koga. 1990. Intranasal immunization of mice with recombinant protein antigen of sero-type c Streptococcus mutans and cholera toxin B subunit. Arch. Oral Biol. 35:475-477.
40. Tamura, S.-I., A. Hideki, Y. Ito, Y. Hirabayashi, Y. Suzuki, T. Nagamine, C. Aizawa, T. Kurata, and A. Ova. 1992. Superior cross-protective effect of nasal vaccination to subcutaneous inoculation with influenza hemagglutinin vaccine. Eur. J. Immunol. 22:477-481.
41. Tilney, N. L. 1971. Patterns of lymphatic drainage in the adult laboratory rat. J. Anat. 109:369-383.
42. van der Ven, L, and T. Sminia, 1993. The development and structure of mouse nasal-associated lymphoid tissue: an immuno- and enzyme-histochemical study. Reg. Immunol. 5:69-75.
43. Walsh, E. E. 1993. Mucosal immunization with a subunit respiratory syncytial virus vaccine in mice. Vaccine 11:1135-1138.
44. Wu, H.-Y., E. B. Nikolova, K. W. Beagley, and M. W. Russell. 1996. Induction of antibody-secreting cells and T helper and memory cells in murine nasal-associated lymplioid tissue. Immunology 88:493-500.
45. Wu, H.-Y., and M. W. Russell. 1993. Induction of mucosal immunity by intranasal application of u streptococcal surface protein antigen with the cholera toxin B subunit. Infect. Immun. 61:314-322.
46. Wu, H.-Y., and M. W. Russell. Unpublished observations.