Synthesis and evaluation of new hydrazide derivatives as neuropeptide Y Y 5 receptor antagonists for the treatment of obesity

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 17, 2004, Pages 4717-4723

  Juanenea, Laura ^a   Galiano, Silvia ^a   Erviti, Oihana ^a   Moreno, Antonio ^a   Pérez, Silvia ^a   Aldana, Ignacio ^a   Monge, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Food intake; Hydrazide; NPY; Obesity; Y 5 receptor antagonists

Indexed keywords

HYDRAZIDE DERIVATIVE; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y5 RECEPTOR;

ARTICLE; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; FEEDING BEHAVIOR; HUMAN; HUMAN CELL; IC 50; NEUROBLASTOMA CELL; OBESITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-OBESITY AGENTS; BINDING, COMPETITIVE; CELL LINE; HUMANS; HYDRAZINES; INHIBITORY CONCENTRATION 50; NEUROPEPTIDE Y; OBESITY; RECEPTORS, NEUROPEPTIDE Y; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 3843140519     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.06.023     Document Type: Article

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