Activation of 5-HT2 receptors enhances the release of acetylcholine in the prefrontal cortex and hippocampus of the rat

Synapse

Volumn 53, Issue 4, 2004, Pages 202-207

  Nair, Sunila G ^a   Gudelsky, Gary A ^a  

^a UNIVERSITY OF CINCINNATI   (United States)

Author keywords

1 (2,5 dimethoxy 4 iodophenyl) 2 aminopropane hydrochloride (DOI); 6 chloro 2 (1 piperazinyl) pyrazine) (MK 212); LY 53,857; Mescaline; Microdialysis

Indexed keywords

1 ISOPROPYL 6 METHYLERGOLINE 8 CARBOXYLIC ACID 2 HYDROXY 1 METHYLPROPYL ESTER; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; FENFLURAMINE; FLUOXETINE; MESCALINE; NORFENFLURAMINE; RECEPTOR SUBTYPE; SEROTONIN 2 RECEPTOR; ACETYLCHOLINE; SEROTONIN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SLICE; CHOLINERGIC NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MICRODIALYSIS; MOLECULAR INTERACTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PARASYMPATHETIC INNERVATION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RECEPTOR UPREGULATION; STIMULUS RESPONSE; SYNAPTIC TRANSMISSION; ANIMAL; CHOLINERGIC NERVE; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY; REACTION TIME; SECRETION; SPRAGUE DAWLEY RAT; SYNAPTOSOME;

ACETYLCHOLINE; ANIMALS; CHOLINERGIC FIBERS; HIPPOCAMPUS; MALE; MICRODIALYSIS; PREFRONTAL CORTEX; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, SEROTONIN, 5-HT2; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SYNAPTIC TRANSMISSION;

EID: 3843123287     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.20054     Document Type: Article

References (37)

1. Acquas E, Fibiger HC. 1998. Dopaminergic regulation of striatal acetylcholine release: the critical role of acetylcholinesterase inhibition. J. Neurochem 70:1088-1093.
2. Barnes NM, Sharp T. 1999. A review of central 5-HT receptors and their function. Neuropharmacology 38:1083-1152.
3. Boess FG, Martin IL. 1994. Molecular biology of 5-HT receptors. Neuropsychopharmacology 33:275-317.
4. Clineschmidt B. 1979. MK-212: a serotonin-like agonist in the CNS. Gen Pharmacol 10:287-290.
5. 4 receptor stimulation facilitates acetylcholine release in rat frontal cortex. Neuroreport 5:1230-1232.
6. 3 receptors. J Neurochem 62:2254-2261.
7. 1B receptors. J Pharmacol Exp Ther 277:823-830.
8. Cunningham K, Callahan P, Appel J. 1986. Discriminative stimulus properties of the serotonin agonist MK 212. Psychopharmacology 90:193-197.
9. 2 receptors induces glycogenolysis in the rat brain. Eur J Pharmacol 464:135-140.
10. DeBoer P, Abercrombie ED. 1996. Physiological release of striatal acetylcholine in vivo: modulation of D1 and D2 dopamine receptor subtypes. J Pharmacol Exp Ther 277:775-783.
11. Fujii T, Yoshizawa M, Nakai K, Fujimoto K, Suzuki T, Kawashima K. 1997. Demonstration of the facilitatory role of 8-OH-DPAT on cholinergic transmission in the rat hippocampus using in vivo microdialysis. Brain Res 761:244-249.
12. Hirano H, Day J, Fibiger H. 1995. Serotonergic regulation of acetylcholine release in rat frontal cortex. J Neurochem 65:1139-1145.
13. 1 recognition sites. J Recept Res 8:59-81.
14. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharne EJ, Saxena PR, Humphrey PPA. 1994. VII International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol Rev 46:157-203.
15. 2A receptors minimally contribute to clozapine-induced acetylcholine release in rat medial prefrontal cortex. Brain Res 939:34-42.
16. 1A receptor enhances acetylcholine release in conscious rats. J Neurochem 62:1804-1808.
17. Jones BE, Cuello AC. 1989. Afferents to the basal forebrain cholinergic cell area from the pontomesencephalic catecholamine, serotonin and acetylcholine neurons. Neuroscience 31:37-61.
18. Kennet G. 1993. 5-HT1C receptors and their therapeutic relevance. Curr Opin Invest Drugs 2:317-362.
19. Lucki I, Ward H, Frazer A. 1989. Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluromethylphenyl)piperazine on locomotor activity. J Pharmacol Exp Ther 249:155-164.
20. Moor E, Schirm E, Jasco J, Westerink BH. 1998. Effects of neostigmine and atropine on basal and handling-induced acetylcholine output from ventral hippocampus. Neuroscience 82:819-825.
21. Muramatsu M, Tamaki-Ohahi J, Usuki C, Araki H, Aihara H. 1988. Serotonin-2 receptor mediated regulation of release of acetylcholine by minaprine in cholinergic nerve terminal of hippocampus of the rat. Neuropharmacology 27:603-609.
22. 1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis. Neurosci Res 31:23-29.
23. Ohue T, Koshimura K, Akiyama Y, Akihiro I, Kido T, Takagi Y, Miwa S. 1992. Regulation of acetylcholine release in vivo from rat hippocampus by monoamines as revealed by novel column-switching HPLC with electrochemical detection. Brain Res 572:340-344.
24. Paxinos G, Watson C. 1986. The rat brain in stereotaxic coordinates. New York: Academic Press.
25. 2C receptors. Br J Pharmacol 128:13-20.
26. Quiron R, Richard J, Dam TV. 1985. Evidence for the existence of serotonin type-2 receptors on cholinergic terminals in rat cortex. Brain Res 333:345-349.
27. Rada PV, Mark GP, Hoebel BG. 1993. In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats. I. Inhibition by serotonin. Brain Res 619:98-104.
28. Robinson SE. 1982. Effect of specific serotonergic lesions on cholinergic neurons in the hippocampus, cortex and striatum. Life Sci 32:345-353.
29. Saito H, Matsumoto M, Togashi H, Yoshioka M. 1996. Functional interaction between serotonin and other neuronal systems: focus on in vivo microdialysis studies. Jpn J Pharmacol 70:203-225.
30. Smiley JF, Subramanian M, Mesulam MM. 1999. Monoaminergic-cholinergic interactions in the primate basal forebrain. Neuroscience 93:817-829.
31. Vizi ES, Harsingh LG Jr, Zsilla G. 1981. Evidence of modulatory role of serotonin in acetylcholine release from striatal interneurons. Brain Res 212:89-99.
32. 2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens. Brain Res 781:291-299.
33. Wright DE, Seroogy KB, Lundgren KH, Davis BM, Jennes L. 1995. Comparative localization of serotonin 1A, 1C and 2 receptor mRNA's in rat brain. J Comp Neurol 351:357-373.
34. 4 receptor involvement in the enhancement of acetylcholine release by p-chloroamphetamine in rat frontal cortex. Brain Res 772:95-101.
35. Zaborsky L. 1989. Afferent connections of the forebrain cholinergic projection neurons, with special reference to monoaminergic and peptidergic fibres. In: Frotscher M, Misgeld U, editors. Central cholinergic synaptic transmission. Basel: Birkhauser. p 12-32.
36. Zhelyazkova-Savova M, Giovannini MG, Pepeu G. 1997. Increase in cortical acetylcholine release after systemic administration of chlorophenylpiperazine in the rat: an in vivo microdialysis study. Neurosci Lett 236:151-154.
37. 2C receptors. Pharmacol Res 40:165-170.