-
1
-
-
0025309329
-
DNA interstrand cross-linking and strand break repair in human glioma cell lines of varying [1,3-bis(2-chloroethyl)-nitro-sourea] resistance
-
Ali-Osman F, Srivenugopal K, Berger MS, Stein DE (1990) DNA interstrand cross-linking and strand break repair in human glioma cell lines of varying [1,3-bis(2-chloroethyl)-nitro-sourea] resistance. Anticancer Res 10:677-682
-
(1990)
Anticancer Res
, vol.10
, pp. 677-682
-
-
Ali-Osman, F.1
Srivenugopal, K.2
Berger, M.S.3
Stein, D.E.4
-
2
-
-
0025217061
-
A phase I and pharmacokinetic study of didox administered by 36 h infusion
-
The Cancer Research Campaign Phase I/II Clinical Trials Committee
-
Carmichael J, Cantwell BM, Mannix KA, Veale D, Elford HL, Blackie R, Kerr DJ, Kaye SB, Harris AL (1990) A phase I and pharmacokinetic study of didox administered by 36 h infusion. The Cancer Research Campaign Phase I/II Clinical Trials Committee. Br J Cancer 61:447-450
-
(1990)
Br J Cancer
, vol.61
, pp. 447-450
-
-
Carmichael, J.1
Cantwell, B.M.2
Mannix, K.A.3
Veale, D.4
Elford, H.L.5
Blackie, R.6
Kerr, D.J.7
Kaye, S.B.8
Harris, A.L.9
-
3
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
Chou TC, Talalay P (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22:27-55
-
(1984)
Adv Enzyme Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
4
-
-
84886638520
-
A chemical basis for the antitumor activity of chloroethylnitrosoureas
-
Colvin M, Brundett RB, Cowens W, Jardine I, Ludlum DB (1976) A chemical basis for the antitumor activity of chloroethylnitrosoureas. Biochem Pharmacol 25:695-699
-
(1976)
Biochem Pharmacol
, vol.25
, pp. 695-699
-
-
Colvin, M.1
Brundett, R.B.2
Cowens, W.3
Jardine, I.4
Ludlum, D.B.5
-
5
-
-
0014962872
-
Ribonucleotide reductase and cell proliferation. I. Variations of ribonucleotide reductase activity with tumor growth rate in a series of rat hepatomas
-
Elford HL, Freese M, Passamani E, Morris HP (1970) Ribonucleotide reductase and cell proliferation. I. Variations of ribonucleotide reductase activity with tumor growth rate in a series of rat hepatomas. J Biol Chem 245:5228-5233
-
(1970)
J Biol Chem
, vol.245
, pp. 5228-5233
-
-
Elford, H.L.1
Freese, M.2
Passamani, E.3
Morris, H.P.4
-
6
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, Goodman SN, Hidalgo OF, Vanaclocha V, Baylin SB, Herman JG (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343:1350-1354
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
Baylin, S.B.7
Herman, J.G.8
-
7
-
-
0042170061
-
Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells
-
Figul M, Soling A, Dong HJ, Chou TC, Rainov NG (2003) Combined effects of temozolomide and the ribonucleotide reductase inhibitors didox and trimidox in malignant brain tumor cells. Cancer Chemother Pharmacol 52:41-46
-
(2003)
Cancer Chemother Pharmacol
, vol.52
, pp. 41-46
-
-
Figul, M.1
Soling, A.2
Dong, H.J.3
Chou, T.C.4
Rainov, N.G.5
-
8
-
-
0141682487
-
Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma
-
Frazier JL, Wang PP, Case D, Tyler BM, Pradilla G, Weingart JD, Brem H (2003) Local delivery of minocycline and systemic BCNU have synergistic activity in the treatment of intracranial glioma. J Neurooncol 64:203-209
-
(2003)
J Neurooncol
, vol.64
, pp. 203-209
-
-
Frazier, J.L.1
Wang, P.P.2
Case, D.3
Tyler, B.M.4
Pradilla, G.5
Weingart, J.D.6
Brem, H.7
-
9
-
-
0018640548
-
A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleotide triphosphates in cell extracts
-
Garrett C, Santi DV (1979) A rapid and sensitive high pressure liquid chromatography assay for deoxyribonucleotide triphosphates in cell extracts. Anal Biochem 99:268-273
-
(1979)
Anal Biochem
, vol.99
, pp. 268-273
-
-
Garrett, C.1
Santi, D.V.2
-
10
-
-
0027515432
-
Chemotherapy for malignant gliomas
-
Huntingt
-
Kyritsis AP (1993) Chemotherapy for malignant gliomas. Oncology (Huntingt) 7:93-100; discussion 103, 106
-
(1993)
Oncology
, vol.7
, pp. 93-100
-
-
Kyritsis, A.P.1
-
11
-
-
0018601662
-
Preliminary results of a phase III comparison study of BCNU, hydroxyurea and radiation to BCNU and radiation
-
Levin VA, Wilson CB, Davis R, Wara W, Pischer TL, Irwin L (1979) Preliminary results of a phase III comparison study of BCNU, hydroxyurea and radiation to BCNU and radiation. Int J Radiat Oncol Biol Phys 5:1573-1576
-
(1979)
Int J Radiat Oncol Biol Phys
, vol.5
, pp. 1573-1576
-
-
Levin, V.A.1
Wilson, C.B.2
Davis, R.3
Wara, W.4
Pischer, T.L.5
Irwin, L.6
-
12
-
-
0018533686
-
A phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas
-
Levin VA, Wilson CB, Davis R, Wara WM, Pischer TL, Irwin L (1979) A phase III comparison of BCNU, hydroxyurea, and radiation therapy to BCNU and radiation therapy for treatment of primary malignant gliomas. J Neurosurg 51:526-532
-
(1979)
J Neurosurg
, vol.51
, pp. 526-532
-
-
Levin, V.A.1
Wilson, C.B.2
Davis, R.3
Wara, W.M.4
Pischer, T.L.5
Irwin, L.6
-
13
-
-
0022003270
-
Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas
-
Levin VA, Wara WM, Davis RL, Vestnys P, Resser KJ, Yatsko K, Nutik S, Gutin PH, Wilson CB (1985) Phase III comparison of BCNU and the combination of procarbazine, CCNU, and vincristine administered after radiotherapy with hydroxyurea for malignant gliomas. J Neurosurg 63:218-223
-
(1985)
J Neurosurg
, vol.63
, pp. 218-223
-
-
Levin, V.A.1
Wara, W.M.2
Davis, R.L.3
Vestnys, P.4
Resser, K.J.5
Yatsko, K.6
Nutik, S.7
Gutin, P.H.8
Wilson, C.B.9
-
14
-
-
0038473995
-
Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: A New Approaches to Brain Tumor Therapy CNS Consortium trial
-
Olivi A, Grossman SA, Tatter S, Barker F, Judy K, Olsen J, Bruce J, Hilt D, Fisher J, Piantadosi S (2003) Dose escalation of carmustine in surgically implanted polymers in patients with recurrent malignant glioma: a New Approaches to Brain Tumor Therapy CNS Consortium trial. J Clin Oncol 21:1845-1849
-
(2003)
J Clin Oncol
, vol.21
, pp. 1845-1849
-
-
Olivi, A.1
Grossman, S.A.2
Tatter, S.3
Barker, F.4
Judy, K.5
Olsen, J.6
Bruce, J.7
Hilt, D.8
Fisher, J.9
Piantadosi, S.10
-
15
-
-
0030029803
-
In vitro and in vivo inhibition of glioblastoma and neuroblastoma with MDL101731, a novel ribonucleoside diphosphate reductase inhibitor
-
Piepmeier JM, Rabidou N, Schold SC Jr, Bitonti AJ, Prakash NJ, Bush TL (1996) In vitro and in vivo inhibition of glioblastoma and neuroblastoma with MDL101731, a novel ribonucleoside diphosphate reductase inhibitor. Cancer Res 56:359-361
-
(1996)
Cancer Res
, vol.56
, pp. 359-361
-
-
Piepmeier, J.M.1
Rabidou, N.2
Schold Jr., S.C.3
Bitonti, A.J.4
Prakash, N.J.5
Bush, T.L.6
-
16
-
-
0034680687
-
The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells
-
Rosenberger G, Fuhrmann G, Grusch M, Fassl S, Elford HL, Smid K, Peters GJ, Szekeres T, Krupitza G (2000) The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells. Life Sci 67:3131-3142
-
(2000)
Life Sci
, vol.67
, pp. 3131-3142
-
-
Rosenberger, G.1
Fuhrmann, G.2
Grusch, M.3
Fassl, S.4
Elford, H.L.5
Smid, K.6
Peters, G.J.7
Szekeres, T.8
Krupitza, G.9
-
17
-
-
0026356576
-
Phase II trial of didox in advanced breast cancer
-
Cancer Research Campaign Phase I/II Clinical Trials Committee
-
Rubens RD, Kaye SB, Soukop M, Williams CJ, Brampton MH, Harris AL (1991) Phase II trial of didox in advanced breast cancer. Cancer Research Campaign Phase I/II Clinical Trials Committee. Br J Cancer 64:1187-1188
-
(1991)
Br J Cancer
, vol.64
, pp. 1187-1188
-
-
Rubens, R.D.1
Kaye, S.B.2
Soukop, M.3
Williams, C.J.4
Brampton, M.H.5
Harris, A.L.6
-
18
-
-
0031046459
-
Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors
-
Sipos EP, Tyler B, Piantadosi S, Burger PC, Brem H (1997) Optimizing interstitial delivery of BCNU from controlled release polymers for the treatment of brain tumors. Cancer Chemother Pharmacol 39:383-389
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 383-389
-
-
Sipos, E.P.1
Tyler, B.2
Piantadosi, S.3
Burger, P.C.4
Brem, H.5
-
19
-
-
0031464519
-
The enzyme ribonucleotide reductase: Target for antitumor and anti-HIV therapy
-
Szekeres T, Fritzer-Szekeres M, Elford HL (1997) The enzyme ribonucleotide reductase: target for antitumor and anti-HIV therapy. Crit Rev Clin Lab Sci 34:503-528
-
(1997)
Crit Rev Clin Lab Sci
, vol.34
, pp. 503-528
-
-
Szekeres, T.1
Fritzer-Szekeres, M.2
Elford, H.L.3
-
20
-
-
0019459845
-
Role of ribonucleotide reductase in expression in the neoplastic program
-
Takeda E, Weber G (1981) Role of ribonucleotide reductase in expression in the neoplastic program. Life Sci 28:1007-1014
-
(1981)
Life Sci
, vol.28
, pp. 1007-1014
-
-
Takeda, E.1
Weber, G.2
-
21
-
-
0026002571
-
Studies on the mechanism of inhibition of L-1210 cell growth by 3,4-dihydroxybenzamic acid and 3,4-dihydrohybenzamidoxime
-
Tihan T, Elford HL, Cory JG (1991) Studies on the mechanism of inhibition of L-1210 cell growth by 3,4-dihydroxybenzamic acid and 3,4- dihydrohybenzamidoxime. Adv Enzyme Regul 31:71-83
-
(1991)
Adv Enzyme Regul
, vol.31
, pp. 71-83
-
-
Tihan, T.1
Elford, H.L.2
Cory, J.G.3
-
22
-
-
0018701235
-
Synthesis of hydroxy- and amino-substituted benzohydroxamic acids: Inhibition of ribonucleotide reductase and antitumor activity
-
Van't Riet B, Wampler GL, Elford HL (1979) Synthesis of hydroxy- and amino-substituted benzohydroxamic acids: inhibition of ribonucleotide reductase and antitumor activity. J Med Chem 22:589-592
-
(1979)
J Med Chem
, vol.22
, pp. 589-592
-
-
Van't Riet, B.1
Wampler, G.L.2
Elford, H.L.3
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