Optimization and validation of a gas chromatographic method for analysis of (RS,SR)-diastereoisomeric impurity in formoterol fumarate

Journal of Chromatography A

Volumn 1045, Issue 1-2, 2004, Pages 211-216

  Akapo, Samuel O ^a   Wegner, Mark ^a   Mamangun, Anicia ^a   McCrea, Chithra ^a   Asif, Muhammad ^a   Dussex, Jean Charles ^b  

^a Analytical Development   (United States)

^b Genchem Pharma Ltd   (Switzerland)

Author keywords

Diastereomer; Formoterol fumarate; Validation

Indexed keywords

DERIVATIVES; GAS CHROMATOGRAPHY; IMPURITIES; LIQUID CHROMATOGRAPHY;

PROCESS IMPURITIES; SILYLATION;

ISOMERS;

FORMOTEROL FUMARATE; IMIDAZOLE DERIVATIVE; N (TRIMETHYLSILYL)IMIDAZOLE; N,N DIMETHYLFORMAMIDE; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ETHANOLAMINE DERIVATIVE; FORMOTEROL;

ACCURACY; ANALYTIC METHOD; ARTICLE; DIASTEREOISOMER; ENANTIOMER; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITY CONTROL; ROOM TEMPERATURE; SILYLATION; VALIDATION PROCESS; CHEMISTRY; METHODOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; STEREOISOMERISM; VALIDATION STUDY;

ADRENERGIC BETA-AGONISTS; CHROMATOGRAPHY, GAS; ETHANOLAMINES; QUALITY CONTROL; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 3843090357     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.06.023     Document Type: Article

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