메뉴 건너뛰기




Volumn 49, Issue 7, 2004, Pages 349-354

Down-regulation of Bcl-2 in the fetal brain of the Gaucher disease mouse model: A possible role in the neuronal loss

Author keywords

Bcl 2; Brain; DNA microarray; Fetus; Gaucher disease; Glucocerebrosidase; Mouse; Neuronal loss

Indexed keywords

COMPLEMENTARY DNA; PROTEIN BCL 2;

EID: 3843077293     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10038-004-0155-2     Document Type: Article
Times cited : (22)

References (19)
  • 2
    • 0013927537 scopus 로고
    • Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease
    • Brady RO, Kanfer JN, Bradley RM, Shapiro D (1966) Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease. J Clin Invest 45:1112-1115
    • (1966) J Clin Invest , vol.45 , pp. 1112-1115
    • Brady, R.O.1    Kanfer, J.N.2    Bradley, R.M.3    Shapiro, D.4
  • 3
    • 0029047946 scopus 로고
    • Bcl-2 transgene expression can protect neurons against developmental and induced cell death
    • Farlie PG, Dringen R, Ress SM, Kannourakis G, Bernard O (1995) Bcl-2 transgene expression can protect neurons against developmental and induced cell death. Proc Natl Acad Sci USA 92:4397-4401
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4397-4401
    • Farlie, P.G.1    Dringen, R.2    Ress, S.M.3    Kannourakis, G.4    Bernard, O.5
  • 4
    • 0034019274 scopus 로고    scopus 로고
    • Severe type II Gaucher disease with ichthyosis, arthrogryposis and neuronal apoptosis: Molecular and pathological analyses
    • Finn LS, Zhang M, Chen SH, Scott CR (2000) Severe type II Gaucher disease with ichthyosis, arthrogryposis and neuronal apoptosis: molecular and pathological analyses. Am J Med Genet 91:222-226
    • (2000) Am J Med Genet , vol.91 , pp. 222-226
    • Finn, L.S.1    Zhang, M.2    Chen, S.H.3    Scott, C.R.4
  • 5
    • 0023138332 scopus 로고
    • Lysosphingolipids inhibit protein kinase C: Implications for the sphigolipidoses
    • Hannun YA, Bell RM (1987) Lysosphingolipids inhibit protein kinase C: implications for the sphigolipidoses. Science 235:670-674
    • (1987) Science , vol.235 , pp. 670-674
    • Hannun, Y.A.1    Bell, R.M.2
  • 6
    • 0023891786 scopus 로고
    • Inhibition of cytochrome c oxidase and hemolysis caused by lysosphingosine
    • Igisu H, Hamasaki N, Ito A, Ou W (1988) Inhibition of cytochrome c oxidase and hemolysis caused by lysosphingosine. Lipids 23:345-348
    • (1988) Lipids , vol.23 , pp. 345-348
    • Igisu, H.1    Hamasaki, N.2    Ito, A.3    Ou, W.4
  • 7
    • 0022494415 scopus 로고
    • Type 2 and type 3 Gaucher disease: A morphological and biochemical study
    • Kaye EM, Ullman MD, Wilson ER, Barranger JA (1986) Type 2 and type 3 Gaucher disease: a morphological and biochemical study. Ann Neurol 20:223-230
    • (1986) Ann Neurol , vol.20 , pp. 223-230
    • Kaye, E.M.1    Ullman, M.D.2    Wilson, E.R.3    Barranger, J.A.4
  • 8
    • 0242637088 scopus 로고    scopus 로고
    • Lysoglycosphingolipids mobilize calcium from brain microsomes via multiple mechanisms
    • Lloyd-Evans E, Felled D, Riebeling G, Futerman AH (2003) Lysoglycosphingolipids mobilize calcium from brain microsomes via multiple mechanisms. Biochem J 375:561-565
    • (2003) Biochem J , vol.375 , pp. 561-565
    • Lloyd-Evans, E.1    Felled, D.2    Riebeling, G.3    Futerman, A.H.4
  • 9
    • 1842456916 scopus 로고    scopus 로고
    • Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development
    • Michaelidis TM, Sendtner M, Cooper JD, Airaksinen MS, Holtmann B, Meyer M, Thoenen H (1996) Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development. Neuron 17:75-89
    • (1996) Neuron , vol.17 , pp. 75-89
    • Michaelidis, T.M.1    Sendtner, M.2    Cooper, J.D.3    Airaksinen, M.S.4    Holtmann, B.5    Meyer, M.6    Thoenen, H.7
  • 11
    • 0036387220 scopus 로고    scopus 로고
    • Glucosylsphingosine accumulation in tissues from patients with Gaucher disease: Correlation with phenotype and genotype
    • Orvisky E, Park JK, LaMarca ME, Ginns EI, Martin BM, Tayebi N, Sidransky E (2002) Glucosylsphingosine accumulation in tissues from patients with Gaucher disease: correlation with phenotype and genotype. Mol Genet Metab 76:262-270
    • (2002) Mol Genet Metab , vol.76 , pp. 262-270
    • Orvisky, E.1    Park, J.K.2    LaMarca, M.E.3    Ginns, E.I.4    Martin, B.M.5    Tayebi, N.6    Sidransky, E.7
  • 12
    • 0034088326 scopus 로고    scopus 로고
    • The increased sensitivity of neurons with elevated glucocerebroside to neurotoxic agents can be reversed by imiglucerase
    • Felled D, Shogomori H, Futerman AH (2000) The increased sensitivity of neurons with elevated glucocerebroside to neurotoxic agents can be reversed by imiglucerase. J Inherit Metab Dis 23:175-184
    • (2000) J Inherit Metab Dis , vol.23 , pp. 175-184
    • Felled, D.1    Shogomori, H.2    Futerman, A.H.3
  • 14
    • 0030071041 scopus 로고    scopus 로고
    • Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation
    • Sakakura C, Sweeney EA, Shirahama T, Hakomori SI, Igarashi Y (1996) Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation. FEBS Lett 379:177-180
    • (1996) FEBS Lett , vol.379 , pp. 177-180
    • Sakakura, C.1    Sweeney, E.A.2    Shirahama, T.3    Hakomori, S.I.4    Igarashi, Y.5
  • 15
    • 0346218248 scopus 로고    scopus 로고
    • Toxicity of glucosylsphingosine to cultured neuronal cells: A model system for assessing neuronal damage in Gaucher disease type 2 and 3
    • Schueler UH, Kolter T, Kaneski CR, Blusztajn JK, Herkenham M, Sandhoff K, Brady RO (2003) Toxicity of glucosylsphingosine to cultured neuronal cells: a model system for assessing neuronal damage in Gaucher disease type 2 and 3. Neurobiol Dis 14:595-601
    • (2003) Neurobiol Dis , vol.14 , pp. 595-601
    • Schueler, U.H.1    Kolter, T.2    Kaneski, C.R.3    Blusztajn, J.K.4    Herkenham, M.5    Sandhoff, K.6    Brady, R.O.7
  • 16
    • 0026322568 scopus 로고
    • Modulation of renal epithelial cell growth by glucosylceramide: Association with protein kinase C, sphingosine and diacylglycerol
    • Shayman JA, Deshmukh GD, Mahdiyoun S, Thomas TP, Wu D, Barcelon FS, Radin NS (1991) Modulation of renal epithelial cell growth by glucosylceramide: association with protein kinase C, sphingosine and diacylglycerol. J Biol Chem 266:22968-22974
    • (1991) J Biol Chem , vol.266 , pp. 22968-22974
    • Shayman, J.A.1    Deshmukh, G.D.2    Mahdiyoun, S.3    Thomas, T.P.4    Wu, D.5    Barcelon, F.S.6    Radin, N.S.7
  • 17
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98:5116-5121
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 19
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
    • Yang YH, Dudoit S, Luu P, Lin DM, Peng V, Ngai J, Speed TP (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30:e15
    • (2002) Nucleic Acids Res , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3    Lin, D.M.4    Peng, V.5    Ngai, J.6    Speed, T.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.