Differences in treatment outcome for hepatitis C among ethnic groups

American Journal of Medicine

Volumn 117, Issue 3, 2004, Pages 163-168

  Hepburn, Matthew J ^a,c   Hepburn, Lisa M ^b   Cantu, Norma S ^a   Lapeer, Maria G ^a   Lawitz, Eric J ^a  

^a BROOKE ARMY MEDICAL CENTER   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; REBETRON; RIBAVIRIN; VIRUS RNA; INTERFERON;

ADULT; AFRICAN AMERICAN; ARTICLE; ASIAN; CLINICAL TRIAL; ETHNOLOGY; EUROPEAN AMERICAN; FEMALE; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HISPANIC; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SELF REPORT; TREATMENT OUTCOME; ASIAN AMERICAN; CAUCASIAN; COMPARATIVE STUDY; CONTROLLED STUDY; ETHNIC GROUP; HEPATITIS C, CHRONIC; MIDDLE AGED; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL;

ADULT; AFRICAN AMERICANS; ASIAN AMERICANS; ETHNIC GROUPS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEPATITIS C, CHRONIC; HISPANIC AMERICANS; HUMANS; INTERFERONS; MALE; MIDDLE AGED; RIBAVIRIN; TREATMENT OUTCOME;

EID: 3843074028     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjmed.2004.02.043     Document Type: Article

References (23)

1. National Institutes of Health Consensus Development Conference Panel Statement: management of hepatitis C: 2002-June 10-12, 2002. Hepatology. 2002; 36(suppl):S3-S15.
2. Alter M.J., Druszon-Moran D., Nainan O.V., et al. The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. N Engl J Med. 341:1999;556-562
3. Kim W.R. Global epidemiology and burden of hepatitis C. Microbes Infect. 4:2002;1219-1225
4. Lindsay K.L. Introduction to therapy of hepatitis C. Hepatology. 36:(suppl):2002;S114-S120
5. De Maria N., Colantoni A., Idilman R., et al. Impaired response to high-dose interferon treatment in African Americans with chronic hepatitis C. Hepatogastroenterology. 49:2002;788-792
6. Howell C., Jeffers L., Hoofnagle J.H. Hepatitis C in African Americans Summary of a workshop. Gastroenterology. 119:2000;1385-1396
7. Kinzie J.L., Naylor P.H., Nathani M.G., et al. African Americans with genotype 1 treated with interferon for chronic hepatitis C have a lower end of treatment response than Caucasians. J Viral Hepatol. 8:2001;264-269
8. McHutchison J.G., Poynard T., Pianko S., et al. The impact of interferon plus ribavirin on response to therapy in black patients with chronic hepatitis C. Gastroenterology. 119:2000;1317-1323
9. Morelli J., Kim C.Y., Willner I.R. US veterans' experience with Rebetron in a nonstudy environment Success or failure? Am J Gastroenterol. 97:2002;2379-2382
10. Reddy K.R., Hoofnagle J.H., Tong M.J., et al. Racial differences in responses to therapy with interferon in chronic hepatitis C. Consensus Interferon Study Group. Hepatology. 30:1999;787-793
11. Theodore D., Shiffman M.L., Sterling R.K., et al. Intensive interferon therapy does not increase virologic response rates in African Americans with chronic hepatitis C. Dig Dis Sci. 48:2003;140-145
12. Dev A.T., McCaw R., Sundararajan V., et al. Southeast Asian patients with chronic hepatitis C The impact of novel genotypes and race on treatment outcome. Hepatology. 36:2002;1259-1265
13. The French METAVIR Cooperative Study Group. Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology. 20:1994;15-20
14. Mallat D.B., Jeffers L. The natural history of HCV infection in African Americans. Am J Gastroenterol. 97:2002;520-522
15. Wiley T.E., Brown J., Chan J. Hepatitis C infection in African Americans Its natural history and histological progression. Am J Gastroenterol. 97:2002;700-706
16. Bonacini M., Groshen S., Yu M.C., et al. Chronic hepatitis C in ethnic minority patients evaluated in Los Angeles county. Am J Gastroenterol. 96:2001;2438-2441
17. Thio C.L., Thomas D.L., Goedert J.J., et al. Racial differences in HLA class II associations with hepatitis C virus outcomes. J Infect Dis. 184:2001;16-21
18. Kimball P., Elswick R.K., Shiffman M. Ethnicity and cytokine production gauge response of patients with hepatitis C to interferon-α therapy. J Med Virol. 65:2001;510-516
19. Sugimoto K., Stadanlick J., Ikeda F., et al. Influence of ethnicity in the outcome of hepatitis C virus infection and cellular immune response. Hepatology. 37:2003;590-599
20. Azocar J., Clavijo O.P., Yunis E.J. MHC class II genes in HCV viral clearance of hepatitis C-infected Hispanic patients. Hum Immunol. 64:2003;99-102
21. Kaufman J.S., Cooper R.S. Commentary Considerations for use of racial/ethnic classification in etiologic research. Am J Epidemiol. 154:2001;291-298
22. Williams D.R. Race and health Basic questions, emerging directions. Ann Epidemiol. 7:1997;322-333
23. Witzig R. The medicalization of race Scientific legitimization of a flawed social construct. Ann Intern Med. 125:1996;675-679