메뉴 건너뛰기




Volumn 39, Issue 1, 2008, Pages 25-36

Presence of residual beta cells and co-existing islet autoimmunity in the NOD mouse during longstanding diabetes: A combined histochemical and immunohistochemical study

Author keywords

Beta cells; Diabetes; Glucose transporter 2; Insulitis; NOD mouse

Indexed keywords

GLUCAGON; GLUCOSE; GLUCOSE TRANSPORTER 2; INSULIN; SOMATOSTATIN;

EID: 38349177483     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10735-007-9122-5     Document Type: Article
Times cited : (12)

References (29)
  • 2
    • 0034042959 scopus 로고    scopus 로고
    • Islet growth and development in the adult
    • Bonner-Weir S (2000) Islet growth and development in the adult. J Mol Endocrinol 24:297-302
    • (2000) J Mol Endocrinol , vol.24 , pp. 297-302
    • Bonner-Weir, S.1
  • 3
    • 0021875480 scopus 로고
    • In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
    • Bottazzo GF, Dean BM, McNally JM, McKay EH, Swift PGF, Gamble DR (1985) In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. New Engl J Med 313:353-360
    • (1985) New Engl J Med , vol.313 , pp. 353-360
    • Bottazzo, G.F.1    Dean, B.M.2    McNally, J.M.3    McKay, E.H.4    Swift, P.G.F.5    Gamble, D.R.6
  • 4
    • 0024563945 scopus 로고
    • Cyclophosphamide-induced diabetes in NOD/WEHI mice: Evidence for suppression in spontaneous autoimmune diabetes mellitus
    • Charlton B, Bacelj A, Slattery RM, Mandel TE (1989) Cyclophosphamide- induced diabetes in NOD/WEHI mice: evidence for suppression in spontaneous autoimmune diabetes mellitus. Diabetes 38:441-447
    • (1989) Diabetes , vol.38 , pp. 441-447
    • Charlton, B.1    Bacelj, A.2    Slattery, R.M.3    Mandel, T.E.4
  • 6
    • 0021252607 scopus 로고
    • The pancreas in recent-onset Type 1(insulin-dependent) diabetes mellitus: Insulin content of islets, insulitis and associated changes in the exocrine acinar tissue
    • Foulis AK, Stewart JA (1984) The pancreas in recent-onset Type 1(insulin-dependent) diabetes mellitus: insulin content of islets, insulitis and associated changes in the exocrine acinar tissue. Diabetologia 26:456-461
    • (1984) Diabetologia , vol.26 , pp. 456-461
    • Foulis, A.K.1    Stewart, J.A.2
  • 7
    • 0022475906 scopus 로고
    • The histopathology of the pancreas in Type 1 (insulin-dependent) diabetes mellitus: A 25-year review of deaths in patients under 20 years of age in the United Kingdom
    • Foulis AK, Liddle CN, Farquharson MA, Richmond JA, Weir RS (1986) The histopathology of the pancreas in Type 1 (insulin-dependent) diabetes mellitus: a 25-year review of deaths in patients under 20 years of age in the United Kingdom. Diabetologia 29:267-274
    • (1986) Diabetologia , vol.29 , pp. 267-274
    • Foulis, A.K.1    Liddle, C.N.2    Farquharson, M.A.3    Richmond, J.A.4    Weir, R.S.5
  • 8
    • 0025951776 scopus 로고
    • Insulitis in Type 1 (insulin-dependent) diabetes mellitus in man- macrophages, lymphocytes and interferon-γ containing cells
    • Foulis AK, McGill M, Farquharson MA (1991) Insulitis in Type 1 (insulin-dependent) diabetes mellitus in man- macrophages, lymphocytes and interferon-γ containing cells. J Pathol 165:97-103
    • (1991) J Pathol , vol.165 , pp. 97-103
    • Foulis, A.K.1    McGill, M.2    Farquharson, M.A.3
  • 9
    • 76549198972 scopus 로고
    • Pathological anatomy of the pancreas in juvenile diabetes mellitus
    • Gepts W (1965) Pathological anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 14:619-633
    • (1965) Diabetes , vol.14 , pp. 619-633
    • Gepts, W.1
  • 10
    • 0018183984 scopus 로고
    • Islet cell survival determined by morphology. An immunocytochemical study of the islets of Langerhans in juvenile diabetes mellitus
    • Suppl 1
    • Gepts W, De Mey J (1978) Islet cell survival determined by morphology. An immunocytochemical study of the islets of Langerhans in juvenile diabetes mellitus. Diabetes 27(Suppl 1):251-261
    • (1978) Diabetes , vol.27 , pp. 251-261
    • Gepts, W.1    De Mey, J.2
  • 11
    • 0023682658 scopus 로고
    • Transient co-appearance of glucagon and insulin in the progenitor cells of the rat pancreatic islets
    • Hashimoto T, Kawano H, Daikoku S, Shima K, Taniguchi H, Baba S (1988) Transient co-appearance of glucagon and insulin in the progenitor cells of the rat pancreatic islets. Anat Embryol 178:489-497
    • (1988) Anat Embryol , vol.178 , pp. 489-497
    • Hashimoto, T.1    Kawano, H.2    Daikoku, S.3    Shima, K.4    Taniguchi, H.5    Baba, S.6
  • 12
    • 0022534650 scopus 로고
    • Defect of the first-phase insulin secretion to glucose stimulation in the perfused pancreas of the nonobese diabetic (NOD) mouse
    • Kano Y, Kanatsuna T, Nakamura N, Kitagawa Y, Mori H, Kajiyama S, Nakano K, Kondo M (1986) Defect of the first-phase insulin secretion to glucose stimulation in the perfused pancreas of the nonobese diabetic (NOD) mouse. Diabetes 35:486-490
    • (1986) Diabetes , vol.35 , pp. 486-490
    • Kano, Y.1    Kanatsuna, T.2    Nakamura, N.3    Kitagawa, Y.4    Mori, H.5    Kajiyama, S.6    Nakano, K.7    Kondo, M.8
  • 13
    • 0034091111 scopus 로고    scopus 로고
    • Islet loss and alpha cell expansion in type 1 diabetes induced by multiple low-dose streptozotocin administration in mice
    • Li Z, Karlsson FA, Sandler S (2000) Islet loss and alpha cell expansion in type 1 diabetes induced by multiple low-dose streptozotocin administration in mice. J Endocrinol 165:93-99
    • (2000) J Endocrinol , vol.165 , pp. 93-99
    • Li, Z.1    Karlsson, F.A.2    Sandler, S.3
  • 14
    • 0023618080 scopus 로고
    • Residual insulin positivity and pancreatic atrophy in relation to duration of chronic Type 1 (insulin-dependent) diabetes mellitus and microangiopathy
    • Lohr M, Kloppel G (1987) Residual insulin positivity and pancreatic atrophy in relation to duration of chronic Type 1 (insulin-dependent) diabetes mellitus and microangiopathy. Diabetologia 30:757-762
    • (1987) Diabetologia , vol.30 , pp. 757-762
    • Lohr, M.1    Kloppel, G.2
  • 15
    • 27744603796 scopus 로고    scopus 로고
    • Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: Indirect evidence for islet regeneration?
    • Meier JJ, Bhushan A, Butler AE, Rizza RA, Butler PC (2005) Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration? Diabetologia 48:2221-2228
    • (2005) Diabetologia , vol.48 , pp. 2221-2228
    • Meier, J.J.1    Bhushan, A.2    Butler, A.E.3    Rizza, R.A.4    Butler, P.C.5
  • 18
    • 0023684290 scopus 로고
    • Ontogeny of islet cell antibodies, insulin autoantibodies and insulitis in the non-obese diabetic mouse
    • Reddy S, Bibby NJ, Elliott RB (1988) Ontogeny of islet cell antibodies, insulin autoantibodies and insulitis in the non-obese diabetic mouse. Diabetologia 31:322-328
    • (1988) Diabetologia , vol.31 , pp. 322-328
    • Reddy, S.1    Bibby, N.J.2    Elliott, R.B.3
  • 19
    • 0029063844 scopus 로고
    • Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T cell subsets prior to and following diabetes in the NOD mouse
    • Reddy S, Wu D, Swinney C, Elliott RB (1995) Immunohistochemical analyses of pancreatic macrophages and CD4 and CD8 T cell subsets prior to and following diabetes in the NOD mouse. Pancreas 11:16-25
    • (1995) Pancreas , vol.11 , pp. 16-25
    • Reddy, S.1    Wu, D.2    Swinney, C.3    Elliott, R.B.4
  • 20
    • 0032127578 scopus 로고    scopus 로고
    • Loss of glucose transporter-2 precedes insulin loss in the non-obese diabetic and the low-dose streptozotocin mouse models: A comparative immunohistochemical study by light and confocal microscopy
    • Reddy S, Young M, Poole CA, Ross JM (1998) Loss of glucose transporter-2 precedes insulin loss in the non-obese diabetic and the low-dose streptozotocin mouse models: a comparative immunohistochemical study by light and confocal microscopy. Gen Comp Endocrinol 111:9-19
    • (1998) Gen Comp Endocrinol , vol.111 , pp. 9-19
    • Reddy, S.1    Young, M.2    Poole, C.A.3    Ross, J.M.4
  • 21
    • 0032781045 scopus 로고    scopus 로고
    • An immunohistochemical study of macrophage influx and the co-localization of inducible nitric oxide synthase in the pancreas of non-obese diabetic (NOD) mice during disease acceleration with cyclophosphamide
    • Reddy S, Yip S, Karanam M, Poole CA, Ross JM (1999) An immunohistochemical study of macrophage influx and the co-localization of inducible nitric oxide synthase in the pancreas of non-obese diabetic (NOD) mice during disease acceleration with cyclophosphamide. Histochem J 31:303-314
    • (1999) Histochem J , vol.31 , pp. 303-314
    • Reddy, S.1    Yip, S.2    Karanam, M.3    Poole, C.A.4    Ross, J.M.5
  • 22
    • 0043168123 scopus 로고    scopus 로고
    • Immunohistochemical study of caspase-3-expressing cells within the pancreas of non-obese diabetic mice during cyclophosphamide-accelerated diabetes
    • Reddy S, Bradley J, Ginn S, Pathipati P, Ross JM (2003) Immunohistochemical study of caspase-3-expressing cells within the pancreas of non-obese diabetic mice during cyclophosphamide-accelerated diabetes. Histochem Cell Biol 119:451-461
    • (2003) Histochem Cell Biol , vol.119 , pp. 451-461
    • Reddy, S.1    Bradley, J.2    Ginn, S.3    Pathipati, P.4    Ross, J.M.5
  • 23
    • 26244460028 scopus 로고    scopus 로고
    • Histopathological changes in insulin, glucagon and somatostatin cells in the islets of NOD mice during cyclophosphamide-accelerated diabetes: A combined immunohistochemical and histochemical study
    • Reddy S, Pathipathi P, Bai Y, Robinson E, Ross JM (2005) Histopathological changes in insulin, glucagon and somatostatin cells in the islets of NOD mice during cyclophosphamide-accelerated diabetes: a combined immunohistochemical and histochemical study. J Mol Histology 36:289-300
    • (2005) J Mol Histology , vol.36 , pp. 289-300
    • Reddy, S.1    Pathipathi, P.2    Bai, Y.3    Robinson, E.4    Ross, J.M.5
  • 24
    • 0026437459 scopus 로고
    • Molecular and cellular physiology of GLUT-2, a high-Km facilitated diffusion glucose transporter
    • Thorens B (1992) Molecular and cellular physiology of GLUT-2, a high-Km facilitated diffusion glucose transporter. Int Rev Cytol 137A:209-238
    • (1992) Int Rev Cytol , vol.137 , pp. 209-238
    • Thorens, B.1
  • 26
    • 0019996086 scopus 로고
    • Quantitation of endocrine cell content in the pancreas of non-diabetic and diabetic humans
    • Stefan Y, Orci L, Malaisse-Lagae F, Perrelet A, Patel A, Unger RH (1982) Quantitation of endocrine cell content in the pancreas of non-diabetic and diabetic humans. Diabetes 31:694-700
    • (1982) Diabetes , vol.31 , pp. 694-700
    • Stefan, Y.1    Orci, L.2    Malaisse-Lagae, F.3    Perrelet, A.4    Patel, A.5    Unger, R.H.6
  • 27
    • 0020623615 scopus 로고
    • Cellular composition of the human diabetic pancreas
    • Rahier J, Goebbels RM, Henquin JC (1983) Cellular composition of the human diabetic pancreas. Diabetologia 24:366-371
    • (1983) Diabetologia , vol.24 , pp. 366-371
    • Rahier, J.1    Goebbels, R.M.2    Henquin, J.C.3
  • 28
    • 24144446405 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycaemia in diabetic NOD mice
    • Suarez-Pinzon WL, Yan Y, Power R, Brand SJ, Rabinovitch A (2005) Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycaemia in diabetic NOD mice. Diabetes 54:2596-2601
    • (2005) Diabetes , vol.54 , pp. 2596-2601
    • Suarez-Pinzon, W.L.1    Yan, Y.2    Power, R.3    Brand, S.J.4    Rabinovitch, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.