Heritability of self-reported phobic fear

Behavior Genetics

Volumn 38, Issue 1, 2008, Pages 24-33

  Distel, Marijn A ^a   Vink, Jacqueline M ^a   Willemsen, Gonneke ^a   Middeldorp, Christel M ^a   Merckelbach, Harald L G J ^b   Boomsma, Dorret I ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Assortative mating; Dominance; Fear; Genetics; Twin family study

Indexed keywords

ADULT; AGED; AGORAPHOBIA; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FEAR; FEMALE; GENETICS; HERITABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MATING; PHOBIA; SELF REPORT; TWINS;

ADOLESCENT; ADULT; AGED; ENVIRONMENT; FEAR; FEMALE; HUMANS; LIFE STYLE; MALE; MIDDLE AGED; MODELS, GENETIC; PHENOTYPE; PHOBIC DISORDERS; SIBLINGS;

EID: 38349171835     PISSN: 00018244     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10519-007-9182-z     Document Type: Article

References (55)

1. Bekker MHJ (1996) Agoraphobia and gender: a review. Clin Psychol Rev 16:129-146
2. Bienvenu OJ, Eaton WW (1998) The epidemiology of blood-injection-injury phobia. Psychol Med 28:1129-1136
3. Bijl RV, de Graaf R, Ravelli A, Smit F, Vollebergh WAM (2002) Gender and age-specific first incidence of DSM-III-R psychiatric disorders in the general population - results from the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 37:372-379
4. Bijl RV, Ravelli A, van Zessen G (1998) Prevalence of psychiatric disorder in the general population: results of the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 33:587-595
5. Boomsma DI, de Geus EJC, Vink JM, Stubbe JH, Distel MA, Hottenga JJ et al (2006) Netherlands Twin Register: from twins to twin families. Twin Res Hum Genet 9:849-857
6. Boomsma DI, Vink JM, van Beijsterveldt TC, de Geus EJ, Beem AL, Mulder EJ et al (2002) Netherlands Twin Register: a focus on longitudinal research. Twin Res 5:401-406
7. Curtis GC, Magee WJ, Eaton WW, Wittchen HU, Kessler RC (1998) Specific fears and phobias - epidemiology and classification. Br J Psychiatry 173:212-217
8. Derks EM, Dolan CV, Boomsma DI (2004) Effects of censoring on parameter estimates and power in genetic modeling. Twin Res 7:659-669
9. Fredrikson M, Annas P, Fischer H, Wik G (1996) Gender and age differences in the prevalence of specific fears and phobias. Behav Res Ther 34:33-39
10. Furmark T (2002) Social phobia: overview of community surveys. Acta Psychiatr Scand 105:84-93
11. Fyer AJ, Mannuzza S, Chapman TF, Martin LY, Klein DF (1995) Specificity in familial aggregation of phobic disorders. Arch Gen Psychiatry 52:564-573
12. Garrison RJ, Anderson VE, Reed SC (1968) Assortative marriage. Eugen Q 15:113-127
13. Gillespie NA, Kirk KM, Evans DM, Heath AC, Hickie IB, Martin NG (2004) Do the genetic or environmental determinants of anxiety and depression change with age? A longitudinal study of Australian twins. Twin Res 7:39-53
14. Hall GS (1897) A study of fears. Am J Psychol 8:147-249
15. Henderson AS, Jorm AF, Korten AE, Jacomb P, Christensen H, Rodgers B (1998) Symptoms of depression and anxiety during adult life: evidence for a decline in prevalence with age. Psychol Med 28:1321-1328
16. Hettema JM, Neale MC, Kendler KS (2001) A review and meta-analysis of the genetic epidemiology of anxiety disorders. Am J Psychiatry 158:1568-1578
17. Hettema JM, Neale MC, Myers JM, Prescott CA, Kendler KS (2006) A population-based twin study of the relationship between neuroticism and internalizing disorders. Am J Psychiatry 163:857-864
18. Hettema JM, Prescott CA, Myers JM, Neale MC, Kendler KS (2005) The structure of genetic and environmental risk factors for anxiety disorders in men and women. Arch Gen Psychiatry 62:182-189
19. Jöreskog KG, Sörbom D (1996) PRELIS 2 user's reference guide. Scientific Software International, Chicago
20. Kendler KS, Jacobson KC, Myers J, Prescott CA (2002) Sex differences in genetic and environmental risk factors for irrational fears and phobias. Psychol Med 32:209-217
21. Kendler KS, Karkowski LM, Prescott CA (1999) Fears and phobias: reliability and heritability. Psychol Med 29:539-553
22. Kendler KS, Myers J, Prescott CA, Neale MC (2001) The genetic epidemiology of irrational fears and phobias in men. Arch Gen Psychiatry 58:257-265
23. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1992) The genetic epidemiology of phobias in women. The interrelationship of agoraphobia, social phobia, situational phobia, and simple phobia. Arch Gen Psychiatry 49:273-281
24. Kessler RC, Berglund P, Demler O, Jin R, Walters EE (2005) Lifetime prevalence and age-of-onset distributions' of DSM-IV disorders in the national comorbidity survey replication. Arch Gen Psychiatry 62:593-602
25. Kessler RC, McGonagle KA, Zhao S, Nelson CB, Hughes M, Eshleman S et al (1994) Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 51:8-19
26. Lapouse R, Monk MA (1959) Fears and worries in a representative sample of children. Am J Orthopsychiatry 29:803-818
27. Low N, Cui L, Merikangas KR (2007) Spousal concordance for substance use and anxiety disorders. J Psychiatr Res 41:942-951
28. Maes HHM, Neale MC, Kendler KS, Hewitt JK, Silberg JL, Foley DL et al (1998) Assortative mating for major psychiatric diagnoses in two population-based samples. Psychol Med 28:1389-1401
29. Marks IM (1987) Fears, phobias, and rituals: panic, anxiety, and their disorders. Oxford University Press, New York
30. Marks IM, Mathews AM (1979) Brief standard self-rating for phobic patients. Behav Res Ther 17:263-267
31. Mathews CA, Reus VI (2001) Assortative mating in the affective disorders: a systematic review and meta-analysis. Compr Psychiatry 42:257-262
32. Mendlowicz MV, Stein MB (2000) Quality of life in individuals with anxiety disorders. Am J Psychiatry 157:669-682
33. Merikangas KR (1982) Assortative mating for psychiatric-disorders and psychological traits. Arch Gen Psychiatry 39:1173-1180
34. Middeldorp CM, Birley AJ, Cath DC, Gillespie NA, Willemsen G, Statham DJ et al (2005) Familial clustering of major depression and anxiety disorders in Australian and Dutch twins and siblings. Twin Res Hum Genet 8:609-615
35. Muris P, Merckelbach H (2001) The etiology of childhood specific phobia: a multifactorial model. In: Vasey MW, Dadds MR (eds) The developmental psychopathology of anxiety. Oxford University Press, New York, pp 355-385
36. Neale MC, Boker SM, Xie G, Maes HH (2003) MX: statistical modelling, 6th edn. Richmond
37. Neale MC, Walters EE, Eaves LJ, Kessler RC, Heath AC, Kendler KS (1994a) Genetics of blood-injury fears and phobias: a population-based twin study. Am J Med Genet 54:326-334
38. Neale MC, Walters EE, Eaves LJ, Maes HH, Kendler KS (1994b) Multivariate genetic-analysis of twin-family data on fears - Mx models. Behav Genet 24:119-139
39. Page AC (1994) Blood-injury phobia. Clin Psychol Rev 14:443-461
40. Page AC, Martin NG (1998) Testing a genetic structure of blood-injury-injection fears. Am J Med Genet 81:377-384
41. Posthuma D, Boomsma DI (1999) Adding non twin siblings to increase power. Behav Genet 29:366
42. Posthuma D, Boomsma DI (2000) A note on the statistical power in extended twin designs. Behav Genet 30:147-158
43. Purcell S, Sham PC (2004) Epistasis in quantitative trait locus linkage analysis: interaction or main effect? Behav Genet 34:143-152
44. Rebollo I, Boomsma DI (2006) Genetic analysis of anger: genetic dominance or competitive sibling interaction. Behav Genet 36:216-228
45. Rose RJ, Ditto WB (1983) A developmental-genetic analysis of common fears from early adolescence to early adulthood. Child Dev 54:361-368
46. Saarni SI, Suvisaari J, Sintonen H, Pirkola S, Koskinen S, Aromaa A et al (2007) Impact of psychiatric disorders on health-related quality of life: general population survey. Br J Psychiatry 190:326-332
47. Skre I, Onstad S, Torgersen S, Lygren S, Kringlen E (1993) A twin study of Dsm-III-R anxiety disorders. Acta Psychiatr Scand 88:85-92
48. Skre I, Onstad S, Torgersen S, Lygren S, Kringlen E (2000) The heritability of common phobic fear: a twin study of a clinical sample. J Anxiety Disord 14:549-562
49. Stein MB, Chartier MJ, Lizak MV, Jang KL (2001) Familial aggregation of anxiety-related quantitative traits in generalized social phobia: clues to understanding "disorder" heritability? Am J Med Genet 105:79-83
50. Stevenson J, Batten N, Cherner M (1992) Fears and fearfulness in children and adolescents - a genetic-analysis of twin data. J Child Psychol Psychiatry 33:977-985
51. Sundet JM, Skre I, Okkenhaug JJ, Tambs K (2003) Genetic and environmental causes of the interrelationships between self-reported fears. A study of a non-clinical sample of Norwegian identical twins and their families. Scandin J Psychol 44:97-106
52. Torgersen S (1983) Genetic-factors in anxiety disorders. Arch Gen Psychiatry 40:1085-1089
53. Van Zuuren FJ (1988) The fear questionnaire - some data on validity, reliability and layout. Br J Psychiatry 153:659-662
54. Vink JM, Willemsen G, Stubbe JH, Middeldorp CM, Ligthart RSL, Baas KD et al (2004) Estimating non-response bias in family studies: application to mental health and lifestyle. Eur J Epidemiol 19:623-630
55. Willemsen G, Posthuma D, Boomsma DI (2005) Environmental factors determine where the Dutch live: results from the Netherlands Twin Register. Twin Res Hum Genet 8:312-317