Regioselective synthesis of oxepin- and oxocin-annulated quinolines by combined 'Claisen-rearrangement/olefin-metathesis' reactions

Synthesis

Volumn , Issue 1, 2008, Pages 45-52

  Rotzoll, Sven ^a   Görls, Helmar ^b   Langer, Peter ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Cyclization; Heterocycles; Rearrangement; Ring closing metathesis

Indexed keywords

CLAISEN REARRANGEMENT; HETEROCYCLES; METATHESIS; OXOCIN; QUINOLINES; RING CLOSING METATHESIS;

CYCLIZATION; REACTION KINETICS; REGIOSELECTIVITY; SYNTHESIS (CHEMICAL);

NITROGEN COMPOUNDS;

6 METHYL 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 7,10 DIHYDROBENZO[H]OXEPINO[3,2 C]QUINOLINE; 8 BROMO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,10 DIBROMO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,10 DICHLORO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,10,11 TRICHLORO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,11 DICHLORO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,11 DIMETHYL 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 8,9 DICHLORO 2,5 DIHYDROOXEPINO[3,2 C]QUINOLINE; 9,11,12 TRICHLORO 3,6 DIHYDRO 2H OXECINO[3,2 C]QUINOLINE; OXEPINE DERIVATIVE; OXOCIN DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANNULATION REACTION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CLAISEN REARRANGEMENT; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; RING CLOSING METATHESIS; STEREOCHEMISTRY;

EID: 38349167624     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-990949     Document Type: Article

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