Hypoxia-induced generation of methane in mitochondria and eukaryotic cells - An alternative approach to methanogenesis

Cellular Physiology and Biochemistry

Volumn 21, Issue 1-3, 2008, Pages 251-258

  Ghyczy, Miklós ^a   Torday, Csilla ^b   Kaszaki, József ^b   Szabó, Andrea ^b   Czóbel, Miklós ^b   Boros, Mihály ^b  

^a University of Szeged ^*

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Hypoxia; Oxidative stress; Phosphatidylcholine; Redox homeostasis

Indexed keywords

2 METHYLAMINOETHANOL; CHOLINE; DEANOL; HYDROXYL RADICAL; LUCIGENIN; METHANE; PHOSPHATIDYLCHOLINE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL HYPOXIA; CHEMOLUMINESCENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; EUKARYOTIC CELL; GAS CHROMATOGRAPHY; GRANULOCYTE; METABOLIC INHIBITION; METHANOGENESIS; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PHOSPHORYLATION; PRIORITY JOURNAL; RAT; RESPIRATORY CHAIN; STATISTICAL ANALYSIS;

BOVINAE; EUKARYOTA; RATTUS;

EID: 38349153123     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000113766     Document Type: Article

References (30)

1. Chance B: Cellular oxygen requirements. Fed Proc 1957;16:671-680.
2. Zorov DB, Juhaszova M, Sollott SJ: Mitochondrial ROS-induced ROS release: an update and review. Biochim Biophys Acta 2006;1757:509-517.
3. Ghyczy M, Boros M: Electrophilic methyl groups present in the diet ameliorate pathological states induced by reductive and oxidative stress: a hypothesis. Br J Nutr 2001;85:409-414.
4. Ghyczy M, Torday C, Boros M: Simultaneous generation of methane, carbon dioxide, and carbon monoxide from choline and ascorbic acid: a defensive mechanism against reductive stress? FASEB J 2003;17:1124-1126.
5. Udenfriend S, Clark CT, Axelrod J, Brodie BB: Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation. J Biol Chem 1954;208:731-739.
6. Ferdinandy P, Danial H, Ambrus I, Rothery RA, Schulz R: Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure. Circ Res 2000;87:241-247.
7. Kristal BS, Yu BP: Dietary restriction augments protection against induction of the mitochondrial permeability transition. Free Radic Biol Med 1998;24:1269-1277.
8. Lowry OH, Rosebrough MJ, Far AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-275.
9. Gryglewski RJ, Moncada S, Palmer RMJ: Bioassay of prostacyclin and endothelium derived relaxing factor (EDRF) from porcine aortic endothelial cells. Br J Pharmacol 1986;87:685-694.
10. Rosen EM, Mueller SN, Noveral J, Levine EM: Proliferative characteristics of clonal endothelial cell strains. J Cell Physiol 1981;107:123-127.
11. Jarell B, Levine E, Shapiro S, Williams S, Carabasi A, Mueller S, Thornton S: Human adult endothelial cell growth in culture. J Vasc Surg 1984;1:757-764.
12. Guarnieri C, Georgountzos G, Caldarera I, Flamigni F, Ligabue A: Polyamines stimulate superoxide production in human neutrophils activated by N-fMet-Leu-Phe but not phorbol myristate acetate. Biochim Biophys Acta 1987;30:135-139.
13. de Ridder JJ: The uptake of choline by rat liver mitochondria. Biochim Biophys Acta 1976;49:236-244.
14. Droge W: Redox regulation in anabolic and catabolic processes. Curr Op Clin Nutr Metab Care 2006;9:190-195.
15. Tappia PS, Dent MR, Dhalla NS: Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med 2006;41:349-361.
16. Exton JH: Regulation of phospholipase D. Biochim Biophys Acta 1999;439:121-133.
17. Parinandi NL, Scribner WM, Vepa S, Shi S, Natarajan V: Phospholipase D activation in endothelial cells is redox sensitive. Antiox Redox Signal 1999;1:193-210.
18. Howes RM: The free radical fantasy: a panoply of paradoxes. Ann NY Acad Sci 2006;1067:22-26.
19. Droge W: Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
20. Peled Y, Weinberg D, Hallak A, Gilat T: Factors affecting methane production in humans. Gastrointestinal diseases and alterations of colonic flora. Dig Dis Sci 1987;32:267-271.
21. Thauer RK: Biochemistry of methanogenesis: a tribute to Marjory Stephenson. Microbiology 1998;44:2377-2406.
22. Keppler F, Hamilton JT, Brass M, Rockmann T: Methane emissions from terrestrial plants under aerobic conditions. Nature 2006;439:187-191.
23. Lowe DC: Global change: a green source of surprise. Nature 2006;439:148-149.
24. Romagnuolo J, Schiller D, Bailey RJ: Using breath tests wisely in a gastroenterology practice: an evidence-based review of indications and pitfalls in interpretation. Am J Gastroenterol 2002;97:1113-1126.
25. Levitt MD, Furne JK, Kuskowski M, Ruddy J: Stability of human methanogenic flora over 35 years and a review of insights obtained from breath methane measurements. Clin Gastroenterol Hepatol 2006;4:123-129.
26. Peled Y, Weinberg D, Hallak A, Gilat T: Factors affecting methane production in humans. Gastrointestinal diseases and alterations of colonic flora. Dig Dis Sci 1987;32:267-271.
27. Flick JA, Hamilton SR, Rosales FJ, Perman JA: Methane excretion and experimental colonic carcinogenesis. Dig Dis Sci 1990;35:221-224.
28. Melcher EA, Levitt MD, Slavin JL: Methane production and bowel function parameters in healthy subjects on low-and high-fiber diets. Nutr Cancer 1991;16:85-92.
29. Florin TH, Zhu G, Kirk KM, Martin NG: Shared and unique environmental factors determine the ecology of methanogens in humans and rats. Am J Gastroenterol 2000;95:2872-2879.
30. Vernia P, Camillo MD, Marinaro V, Caprilli R: Effect of predominant methanogenic flora on the outcome of lactose breath test in irritable bowel syndrome patients. Eur J Clin Nutr 2003;57:1116-1119.