Scaffolds from electrospun polyhydroxyalkanoate copolymers: Fabrication, characterization, bioabsorption and tissue response

Biomaterials

Volumn 29, Issue 10, 2008, Pages 1307-1317

  Ying, Tang H ^a,b   Ishii, Daisuke ^c   Mahara, Atsushi ^d   Murakami, Sunao ^d   Yamaoka, Tetsuji ^d   Sudesh, Kumar ^a,b   Samian, Razip ^b   Fujita, Masahiro ^a   Maeda, Mizuo ^a   Iwata, Tadahisa ^c  

^a RIKEN   (Japan)

^b SCHOOL OF PHYSICS   (Malaysia)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Bioabsorption; Electrospun fiber; Polyhydroxyalkanoate; Tissue response

Indexed keywords

BIOCOMPATIBILITY; COPOLYMERS; ELECTROSPINNING; MONOMERS; TISSUE CULTURE;

BIOABSORPTION; ELECTROSPUN FIBER; POLYHYDROXYALKANOATE; TISSUE RESPONSE;

SCAFFOLDS;

4 HYDROXYBUTYRIC ACID; COPOLYMER; POLYHYDROXYALKANOIC ACID; SCAFFOLD PROTEIN;

ARTICLE; BIOSORPTION; CHEMICAL STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; HISTOLOGY; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; TISSUE REACTION; X RAY DIFFRACTION;

ANIMALS; BIOCOMPATIBLE MATERIALS; MALE; MICROSCOPY, ELECTRON, SCANNING; POLYHYDROXYALKANOATES; POLYMERS; RATS; RATS, WISTAR; TISSUE ENGINEERING; X-RAY DIFFRACTION;

RATTUS;

EID: 38349148942     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2007.11.031     Document Type: Article

References (41)

1. Williams S.F., and Martin D.P. Applications of PHAs in medicine and pharmacy. In: Steinbüchel A. (Ed). Series of biopolymers in 10 volumes vol. 4 (2002), Wiley/VCY/Verlag 91-121
2. Chen G.Q., and Wu Q. The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials 26 (2005) 6565-6578
3. FDA clears first of its kind suture made using DNA technology. Available from: (2007 February 12), FDA News. http://www.fda.gov/bbs/topics/NEWS/2007/NEW01560.html [accessed 25.04.07]
4. Anderson A.J., and Dawes E.A. Occurrence, metabolic role, and industrial uses of bacterial polyhydroxyalkanoates. Microbial Rev 54 (1990) 450-472
5. Doi Y. Microbial polyesters (1990), VCH, New York
6. Kato M., Bao H.J., Kang C.K., Fukui T., and Doi Y. Production of a novel copolyester of 3-hydroxybutyric acid and medium-chain-length 3-hydroxyalkanoic acids by Pseudomonas sp. 61-3 from sugars. Appl Microbiol Biotechnol 45 (1996) 363-370
7. Hocking P.J., and Marchessault R.H. Biopolyesters. In: Griffin G.J.L. (Ed). Chemistry and technology of biodegradable polymers (1994), Chapman & Hall, London p. 48-96
8. Nelson T., Kaufman E., Kline E., and Sokoloff L. The extraneural distribution of gammahydroxybutyrate. J Neurochem 37 (1981) 1345-1388
9. Taylor M.S., Daniels A.U., Andriano K.P., and Heller J. Six absorbable polymers: in vitro acute toxicity of accumulated degradation products. J Appl Biomat 5 (1994) 151-157
10. Iwata T., Tsunoda K., Aoyagi Y., Kusaka S., Yonezawa N., and Doi Y. Mechanical properties of uniaxially cold-drawn films of poly[(R)-3-hydroxybutyrate]. Polym Degrad Stab (2003) 217-224
11. Sudesh K., Abe H., and Doi Y. Synthesis, structure and properties of polyhydroxyalkanoates: biological polyesters. Prog Polym Sci 25 (2000) 1503-1555
12. Griffith L.G. Emerging design principles in biomaterials and scaffolds for tissue engineering. Ann N Y Acad Sci 961 (2000) 83-95
13. Zong X., Bien H., Chung C.Y., Yin L., Fang D., Hsiao B.S., et al. Electrospun fine-textured scaffolds for heart tissue constructs. Biomaterials 26 (2005) 5330-5338
14. Li W.J., Laurencin C.T., Caterson E.J., Tuan R.S., and Ko F.K. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Res 60 (2002) 613-621
15. Kim J., and Reneker D.H. Mechanical properties of composites using ultrafine electrospun fibers. Polym Composites 20 (1999) 124-131
16. Lee W.H., Azizan M.N.M., and Sudesh K. Effects of culture conditions on the composition of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) synthesized by Comamonas acidovorans. Polym Degrad Stab 84 (2004) 129-134
17. Siew E.L., Rajab N.F., Osman A., Sudesh K., and Inayat-Hussain S.H. In vitro biocompatibility evaluation of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) copolymer in fibroblast cells. J Biomed Res A 81A (2007) 317-325
18. Dong H., Nyame V., Macdiarmid Jr. A.G., and Jones W.E. Polyaniline/poly(methyl methacrylate) coaxial fibers: the fabrication and effects of the solution properties on the morphology of electrospun core fibers. J Polym Sci Part B: Polym Phys 42 (2004) 3934-3942
19. Lyons J., Li C., and Ko F. Melt-electrospinning part I: processing parameters and geometric properties. Polymer 45 (2004) 7597-7603
20. Fong H., Chun I., and Reneker D.H. Beaded nanofibers formed during electrospinning. Polymer 40 (1999) 4585-4592
21. Zuo W., Zhu M., Yang W., Yu H., Chen Y., and Zhang Y. Experimental study on relationship between jet stability and formation of beaded fibers during electrospinning. Polym Eng Sci 45 (2005) 704-709
22. Zong X., Ran S., Kim K.S., Fang D., Hsiao B.S., and Chu B. Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide nanofiber membrane. Biomacromolecules 4 (2003) 416-423
23. Li W.J., Cooper Jr. J.A., Mauck R.L., and Tuan R.S. Fabrication and characterization of six electrospun poly(α-hydroxyester)-based fibrous scaffolds for tissue engineering applications. Acta Biomaterialia 2 (2006) 377-385
24. Jeong E.H., Im S.S., and Youk J.H. Electrospinning and structural characterization of ultrafine poly(butylenes succinate) fibers. Polymer 4 (2005) 9538-9543
25. Yokouchi M., Chatani Y., Tadokoro H., Teranishi K., and Tani H. Structural studies of polyesters: 5. Molecular and crystal structures of optically active and racemic poly (β-hydroxybutyrate). Polymer 14 (1973) 267-272
26. Su F., Iwata T., Tanaka F., and Doi Y. Crystal structure and enzymatic degradation of poly(4-hydroxybutyrate). Macromolecules 36 (2003) 6401-6409
27. Doi Y., Kanesawa Y., Kawaguchi Y., and Kunioka M. Biodegradation of microbial polyesters in the marine environment. Polym Degrad Stab 32 (1992) 173-177
28. Mitomo H., Hsieh W.C., Nishiwaki K., Kasuya K., and Doi Y. Poly(3-hydroxybutryate-co-4-hydroxybutyrate) produced by Comamonas acidovorans. Polymer 42 (2001) 3455-3461
29. Di Lorenzo M.L., Raimo M., Cascone E., and Martuscelli E. Poly(3-hydroxybutyrate)-based copolymers and blends: influence of a second component on crystallization and thermal behavior. J Macromol Sci Phys 40 (2001) 639-667
30. Gogolewski S. Resorbable polymers for internal fixation. Clin Mater 10 (1992) 13-20
31. Marois Y., Zhang Z., Vert M., Deng X., Lenz R., and Guidoin R. Mechanism and rate of degradation of polyhydroxyoctanoate films in aqueous media: a long term in vitro study. J Biomed Mater Res 49 (2000) 216-224
32. Lo C.M., Wang H.B., Dembo M., and Wang Y.L. Cell movement is guided by the rigidity of the substrate. Biophys J 79 (2000) 144-152
33. Pelham R.J., and Wang Y.L. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 94 (1997) 13661-13665
34. Rappolee D.A., Mark D., Banda M.J., and Werb Z. Wound macrophages express TGF-alpha and other growth factors in vivo: analysis by mRNA phenotyping. Science 241 (1988) 708
35. Martin DP, Skraly FA, Williams SF. Polyhydroxyalkanoate compositions having controlled degradation rats. PCT Patent Application No. WO 99/32536; 1999.
36. Qu X.H., Wu Q., Zhang K.Y., and Chen G.Q. In vivo studies of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) based polymers: biodegradation and tissue reactions. Biomaterials 27 (2006) 3540-3548
37. Ali S.A.M., Doherty P.J., and Williams D.F. Molecular biointeractions of biomedial polymers with extracellular exudates and inflammatory cells and their effects on the biocompatibility in vivo. Biomaterials 15 (1994) 779-785
38. Saad B., Neuenschwander P., Uhlschmid G.K., and Suter U.W. New versatile, elastomeric, degradable polymeric materials for medicine. Intern J Biol Macromol 25 (1999) 293-301
39. Tracy M.A., Ward K.L., Firouzabadian L., Wang Y., Dong N., Qian R., et al. Factors affecting the degradation rate of poly(lactide-co-glycolide) microspheres in vivo and in vitro. Biomaterials 20 (1999) 1057-1062
40. Mukai K., Doi Y., Sema Y., and Tomita K. Substrate specificities in hydrolysis of polyhydroxyalkanoates by microbial esterases. Biotechnol Lett 15 (1993) 601-604
41. Malm T., Bowald S., Bylock A., Busch C., and Saldeen T. Enlargement of the right ventricular outflow tract and the pulmonary artery with a new biodegradable patch in transanular position. Eur Surg Res 26 (1994) 298-308