MMP-1, IL-1β, and COX-2 mRNA expression is modulated by static load in rabbit flexor tendons

Annals of Biomedical Engineering

Volumn 36, Issue 2, 2008, Pages 237-243

  Asundi, Krishna R ^a   Rempel, David M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Mechanotransduction; Organ culture; Overuse injury; Tendon creep

Indexed keywords

CELLS; COMPUTER SIMULATION; CORRELATION THEORY; GENE EXPRESSION; HARVESTING; SYNTHESIS (CHEMICAL);

MECHANOTRANSDUCTION; ORGAN CULTURE; OVERUSE INJURY; TENDON CREEP;

RNA;

CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; MESSENGER RNA;

ANIMAL; ARTICLE; CUMULATIVE TRAUMA DISORDER; GENE EXPRESSION REGULATION; IN VITRO STUDY; MECHANOTRANSDUCTION; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT; TENDON; WEIGHT BEARING;

ANIMALS; CUMULATIVE TRAUMA DISORDERS; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 1; MECHANOTRANSDUCTION, CELLULAR; RABBITS; RNA, MESSENGER; TENDONS; WEIGHT-BEARING;

EID: 38349141806     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-007-9427-2     Document Type: Article

References (41)

1. Abiko Y., N. Shimizu, M. Yamaguchi, H. Suzuki, H. Takiguchi. Effect of aging on functional changes of periodontal tissue cells. Ann. Periodontol. 3: 350-369, 1998
2. Archambault J. M., M. Tsuzaki, W. Herzog, A. Banes. Stretch and interleukin-1beta induce matrix metalloproteinases in rabbit tendon cells in vitro. J. Orthop. Res. 20(1): 36-39, 2002
3. Archambault J. M., J. P. Wiley, R. C. Bray. Exercise loading of tendons and the development of overuse injuries. A review of current literature. Sports Med. 20(2): 77-89, 1995
4. Arnoczky S., T. Tian, M. Lavagnino, K. Gardner. Ex vivo static tensile loading inhibits MMP-1 expression in rat tail tendon cells through a cytoskeletally based mechanotransduction mechanism. J. Orthop. Res. 22(2): 328-333, 2004
5. Asundi, K., K. Kursa, J. Lotz, and D. Rempel. In vitro system for applying cyclic loads to connective tissues under force or displacement control. Ann. Biomed. Eng. 35:1188-1195, 2007
6. Banes A., M. Tsuzaki, J. Yamamoto, T. Fischer, B. Brigman, T. Brown, L. Miller. Mechanoreception at the cellular level: the detection, interpretation, and diversity of responses to mechanical signals. Biochem. Cell Biol. 73: 349-365, 1995
7. Banes A. J., P. Weinhold, X. Yang, M. Tsuzaki, D. Bynum, M. Bottlang, T. Brown. Gap junctions regulate response of tendon cells ex vivo to mechanical loading. Clin. Orthop. Relat. Res. 367: s356-s370, 1999
8. Bankers-Fulbright J., K. Kalli, K. McKean. Interleukin-1 signal transduction. Life Sci. 59: 61-83, 1996
9. Bernard, B. Musculoskeletal disorders and workplace factors. NIOSH Publication 97-141, 1997
10. Butler D., E. Grood, F. R Noyes, R. F. Zernicke, K. Brackett. Effects of structure and strain measurement technique on the material properties of young human tendons and fascia. J. Biomech. 17(8): 579-596, 1984
11. Gillroy D. W., A. Tomlinson, D. A. Willoughby. Differential effects of inhibition of isoforms of cyclooxygenase (COX1, COX2) in chronic inflammation. Inflamm. Res. 47: 79-85, 1998
12. Goldstein S. A., T. J. Armstrong, D. B. Chaffin, L. S. Matthews. Analysis of cumulative strain in tendons and tendon sheaths. J. Biomech. 20: 1-6, 1987
13. Hannafin J. A., S. P. Arnoczky, A. Hoonjan, P. A. Torzilli. Effect of stress deprivation and cyclic tensile loading on material and morphological properties of canine flexor digitorum profundus tendon: an in vitro study. J. Orthop. Res. 13: 907-914, 1995
14. Hanson K., J. Weiss, J. Barton. Recruitment of tendon crimp with applied tensile strain. J. Biomech. Eng. 124: 72-77, 2002
15. Ireland D., R. Harral, V. Curry, G. Holloway, R. Hackney, B. Hazleman, G. Riley. Multiple changes in gene expression in chronic human Achilles tendinopathy. Matrix Biol. 20: 159-169, 2001
16. Jozsa, L., and P. Kannus. In: Human Tendons: Anatomy, Physiology and Pathology. Champaign: Human Kinetics, 1997
17. Koshima H., S. Kondo, S. Mishima, H. R. Choi, H. Shimpo, T. Sakai, N. Ishiguro. Expression of interleukin-1beta, cyclooxygenase-2, and prostaglandin E2 in a rotator cuff tear in rabbits. J. Orthop. Res. 25: 92-97, 2007
18. Lavagnino M., S. P. Arnoczky. In vitro alterations in cytoskeletal tensional homeostasis control gene expression in tendon cells. J. Orthop. Res. 23(5): 1211-1218, 2005
19. Lavagnino M., S. P. Arnoczky, M. Egerbacher, K. L. Gardner, M. E. Burns. Isolated fibrillar damage in tendons stimulates local collagenase mRNA expression and protein synthesis. J. Biomech. 39: 2355-2362, 2006
20. Lavignino M., S. P. Arnoczky, T. Tian, Z. Vaupel. Effect of amplitude and frequency of cyclic tensile stress on the inhibition of MMP-1 mRNA expression in tendon cells: an in vitro study. Connect. Tissue Res. 44: 181-187, 2003
21. Majima T., L. L. Marchuk, N. G. Shrive, C. B. Frank, D. A. Hart. In-vitro cyclic tensile loading of an immobilized and mobilized ligament autograft selectively inhibits mRNA levels for collagenase (MMP-1). J. Orthop. Sci. 5(5): 503-510, 2000
22. Malaviya P., D. Butler, D. Korvick, F. Proch. In vivo tendon forces correlate with activity level and remain bounded: evidence in a rabbit flexor tendon model. J. Biomech. 31:1043-1049, 1998
23. Mansur N. R., K. Meyer-Siegler, J. C. Wurzer, M. A. Sirover. Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells. Nucleic Acid Res. 21(4): 993-998, 1993
24. Matrisian L. M. Metalloproteinases and their inhibitors in matrix remodeling. TIG 6: 121-125, 1990
25. Narumiya S., Y. Sugimoto, F. Ushikubi. Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79: 1193-1226, 1999
26. Okuda Y., J. P. Gorski, K. N. An, P. C. Amadio. Biochemical, histological and biomechanical analyses of canine tendon. J. Orthop. Res. 5: 60-68, 1987
27. Perry S., S. McIlhenny, M. Hoffman, L. Soslowsky. Inflammatory and angiogenic mRNA levels are altered in a supraspinatus tendon overuse animal model. J. Shoulder Elbow Surg. 14(1 Suppl S): 79S-83S, 2005
28. Riley G. P., V. Curry, J. DeGroot, B. van El, N. Verzijl, B. L. Hazleman, R. A. Bank. Matrix metalloproteinase activities and their relationship with collagen remodeling in tendon pathology. Matrix Biol. 21: 185-195, 2002
29. Screen H., D. Lee, D. Bader, J. Shelton. An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties. Proc. Inst. Mech. Eng. [H] 218(2): 109-119, 2004
30. Slack C., M. H. Flint, B. M. Thompson. The effect of tensional load on isolated embryonic chick tendons in organ culture. Connect. Tissue Res. 12: 229-247, 1984
31. Thornton G. M., N. G. Shrive, C. B. Frank. Ligament creep recruits fibres at low stresses and can lead to modulus-reducing fibre damage at higher creep stresses: a study in rabbit medial collateral ligament model. J. Orthop. Res. 20(5): 967-974, 2002
32. Tsuzaki M., D. Bynum, L. Almekinders, X. Yang, J. Faber, A. J. Banes. ATP modulates load-inducible IL-1 beta, COX 2, and MMP-3 gene expression in human tendon cells. J. Cell Biochem. 89(3): 556-562, 2003
33. Tsuzaki M., G. Guyton, W. Garrett, J. M. Archambault, W. Herzog, L. Almekinders, D. Bynum, X. Yang, A. J. Banes. IL-1 beta induces COX2, MMP-1, -3 and -13, ADAMTS-4, IL-1 beta and IL-6 in human tendon cells. J. Orthop. Res. 21(2): 256-264, 2003
34. Uchida H., H. Tohyama, K. Nagashima, Y. Ohba, H. Matsumoto, Y. Toyama, K. Yasuda. Stress deprivation simultaneously induces over-expression of interleukin-1beta, tumor necrosis factor-alpha, and transforming growth factor-beta in fibroblasts and mechanical deterioration of the tissue in the patellar tendon. J. Biomech. 38: 791-798, 2005
35. Wang J. H. Mechanobiology of tendons. J. Biomech. 39: 1563-1582, 2006
36. Wang J. H., F. Jia, G. Yang, S. Yang, B. Campbell, D. Stone, S. L. Woo. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect. Tissue Res. 44: 128-133, 2003
37. Wang X., R. F. Ker. Creep rupture of wallaby tail tendons. J. Exp. Biol. 198: 831-845, 1995
38. Wang X., R. F. Ker, R. M. Alexander. Fatigue rupture of wallaby tail tendons. J. Exp. Biol. 198: 847-852, 1995
39. Wren T. A., D. P. Lindsey, G. S. Beaupre, D. R. Carter. Effects of creep and cyclic loading on the mechanical properties and failure of human Achilles tendons. Ann. Biomed. Eng. 31: 710-717, 2003
40. Yang G., H. J. Im, J. H. Wang. Repetitive mechanical stretching modulates IL-1 beta induced COX-2, MMP-1 expression, and PGE2 production in human patellar tendon fibroblasts. Gene 363: 166-172, 2005
41. Zernicke R. F., D. L. Butler, E. S. Grood, M. S. Hefzy. Strain topography of human tendon and fascia. J. Biomech. Eng. 106: 177-180, 1984