Selection of anti-cancer antibodies from combinatorial libraries by whole-cell panning and stringent subtraction with human blood cells

Journal of Immunological Methods

Volumn 330, Issue 1-2, 2008, Pages 109-119

  Siva, Amara C ^a   Kirkland, Richard E ^a   Lin, Bing ^a   Maruyama, Toshiaki ^a   McWhirter, John ^a   Yantiri Wernimont, Ferda ^a   Bowdish, Katherine S ^a   Xin, Hong ^a  

^a Alexion Antibody Technologies Inc   (United States)

Author keywords

Antibodies; Metastasis; Negative selection; Tumor antigens; Whole cell panning

Indexed keywords

DIPEPTIDYL PEPTIDASE IV;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY LIBRARY; ANTIBODY RESPONSE; ARTICLE; BLOOD CELL; CANCER CELL CULTURE; CELL MIGRATION; CONTROLLED STUDY; ERYTHROCYTE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WHOLE CELL;

ANIMALS; ANTIBODIES, NEOPLASM; ANTIBODY DIVERSITY; ANTIBODY SPECIFICITY; ANTIGENS, CD26; ANTIGENS, NEOPLASM; BINDING SITES, ANTIBODY; CELL LINE, TUMOR; COMBINATORIAL CHEMISTRY TECHNIQUES; CROSS REACTIONS; ERYTHROCYTES; HUMANS; IMMUNIZATION; INTEGRINS; LEUKOCYTES; MALE; MICE; MICE, INBRED BALB C; PEPTIDE LIBRARY; PROSTATIC NEOPLASMS;

MUS;

EID: 38349132689     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2007.11.008     Document Type: Article

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