Uteroglobin-related protein 1 gene -112G/A polymorphism and atopic asthma in Sicilian children

Allergy and Asthma Proceedings

Volumn 28, Issue 6, 2007, Pages 667-670

  Rigoli, Luciana ^a,c   Di Bella, Chiara ^a   Procopio, Vincenzo ^a   Finocchiaro, Giuseppe ^b   Amorini, Maria ^a   Lo Giudice, Giuseppina ^a   Cuppari, Caterina ^a   Salpietro, Carmelo Damiano ^a  

^a Department of Pediatrics

^b UNIVERSITY OF MESSINA   (Italy)

^c UNIVERSITY OF MESSINA   (Italy)

Author keywords

Asthma; Atopy; Automatic sequencing; Bronchial hyperresponsiveness; Genetics; Polymerase chain reaction; Polymorphism; Restriction enzyme; Transmission disequilibrium test; Uteroglobin related protein 1 gene

Indexed keywords

SCGB3A2 PROTEIN, HUMAN; UNCLASSIFIED DRUG; UTEROGLOBIN;

ADOLESCENT; ALLELE; ARTICLE; ASTHMA; CASE CONTROL STUDY; CHILD; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; IMMUNOLOGY; ITALY; MALE;

ADOLESCENT; ALLELES; ASTHMA; CASE-CONTROL STUDIES; CHILD; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; SICILY; UTEROGLOBIN;

EID: 38349118936     PISSN: 10885412     EISSN: None     Source Type: Journal    
DOI: 10.2500/aap.2007.28.3056     Document Type: Article

References (20)

1. Broadley KJ. Beta-adrenoreceptor responses of the airways: For better or worse? Eur J Pharmacol 536:279-286, 2006.
2. Brown RH, Pearse DB, Pyrgos G, et al. The structural basis of airways hyperresponsiveness in asthma. J Appl Physiol 101:30-39, 2006.
3. McFadden ER Jr, and Gilbert IA. Asthma. N Engl J Med 327:1928-1937, 1992.
4. Cookson WO, and Moffatt MF. Genetics of asthma and allergic disease. Hum Mol Genet 9:2359-2364, 2000.
5. Yokouchi Y, Nukaga Y, Shibasaki M, et al. Significant evidence for linkage of mite-sensitive childhood asthma to chromosome 5q31-q33 near the interleukin 12 B locus by a genome-wide search in Japanese families. Genomics 66:152-160, 2000.
6. Niimi T, Keck-Waggoner CL, Popescu NC, et al. UGRP1, a uteroglobin/Clara cell secretory protein-related protein, is a novel lung-enriched downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor. Mol Endocrinol 15:2021-2036, 2001.
7. Niimi T, Munakata M, Keck-Waggoner CL, et al. A polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma. Am J Hum Genet 70:718-725, 2002.
8. Batra J, Niphadkar PV, Sharma SK, et al. Uteroglobin-related protein 1 (UGRP1) gene polymorphisms and atopic asthma in the Indian population. Int Arch Allergy Immunol 136:1-6, 2005.
9. Jian Z, Nakayama J, Noguchi E, et al. No evidence for association between the -112G/A polymorphism of UGRP1 and childhood atopic asthma. Clin Exp Allergy 33:902-904, 2003.
10. Heinzmann A, Dietrich H, and Deichmann KA. Association of uteroglobin-related protein 1 with bronchial asthma. Int Arch Allergy Immunol 131:291-295, 2003.
11. Dreborg S, and Frew A. Position paper: Allergen standardization and skin tests. Allergy 48:49-82, 1993.
12. Sambrook J, Fritsch EF, and Maniatis T. Molecular cloning. In A Laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 9-16, 1989.
13. StataCorp. Stata Statistical Software, Release 9.0. College Station, TX: StataCorp., 2005.
14. Spielman RS, McGinnis RE, and Ewens WJ. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 57:506-516, 1993.
15. Costa RH, Kalinichenko W, and Lim L. Transcription factors in mouse lung development and function. Am J Physiol Lung Cell Mol Physiol 280:L823-L838, 2001.
16. De Burbure C, Pignatti P, Corradi M, et al. Uteroglobin-related protein 1 and Clara cell protein in induced sputum of patients with asthma and rhinitis. Chest 131:172-179, 2007.
17. Chiba Y, Kurotani R, Kusakabe T, et al. Uteroglobin-related protein 1 expression suppresses allergic airway inflammation in mice. Am J Respir Crit Care Med 174:840, 2006.
18. Yamada A, Sheikh F, Niimi T, et al. Induction of uteroglobin-related protein 2 (UGRP2) gene expression by the Th2 cytokines IL-4 and IL-13. J Immunol 175:5708-5715, 2005.
19. Chiba Y, Kusakabe T, and Kimura S. Decreased expression of uteroglobin-related protein 1 in inflammation mouse airways is mediated by IL-9. Am J Physiol Lung Cell Mol Physiol 287:L1193-L1198, 2004.
20. Chiba Y, Srisodsai A, Supavilai P, et al. Interleukin-5 reduces the expression of the uteroglobin-related protein (UGRP1) 1 gene in allergic airway inflammation. Immunol Lett 97:123-129, 2005.