Somatostatin inhibits tooth-pulp-evoked rat cervical dorsal horn neuronal activity

Experimental Brain Research

Volumn 184, Issue 4, 2008, Pages 617-622

  Takahashi, M ^a   Takeda, M ^a   Matsumoto, S ^a  

^a NIPPON DENTAL UNIVERSITY   (Japan)

Author keywords

C1 spinal neurons; Hyperalgesia; Microiontophoresis; Somatostatin; Trigeminal pain

Indexed keywords

CYANAMID 154806; HORMONE RECEPTOR BLOCKING AGENT; PENTOBARBITAL; SOMATOSTATIN; SOMATOSTATIN RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROIONTOPHORESIS; NEUROMODULATION; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; TOOTH PULP;

ANIMALS; CERVICAL VERTEBRAE; DENTAL PULP; ELECTRIC STIMULATION; EVOKED POTENTIALS, SOMATOSENSORY; HORMONES; HYPERALGESIA; IONTOPHORESIS; MALE; NOCICEPTORS; POSTERIOR HORN CELLS; RATS; RATS, WISTAR; SOMATOSTATIN; TOOTHACHE; TRIGEMINAL NEURALGIA;

EID: 38349110221     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-007-1261-0     Document Type: Article

References (28)

1. Bartsch T, Levy MJ, Knight YE, Goadsby PJ (2005) Inhibition of nociceptive dural input in the trigeminal nucleus caudalis by somatostatin receptor blockade in the posterior hypothalamus. Pain 117:30-39
2. Bass RT, Buckwalter BL, Patel BP, Pausch MH, Price LA, Strnad J, Hadcock JR (1996) Identification and characterization of novel somatostatin antagonists. Mol Pharmacol 50(4):709-715
3. Bassant MH, Simon A, Poindessous-Jazat F, Csaba Z, Epelbaum J, Dournaud P (2005) Medial septal GABAergic neurons express the somatostatin sst2A receptor: functional consequences on unit firing and hippocampal theta. J Neurosci 25:2032-2041
4. Bereiter DA (1997) Morphine and somatostatin analogue reduce c-Fos expression in trigeminal subnucleus caudalis produced by corneal stimulation in the rat. Neuroscience 77:863-874
5. Carlton SM, Du J, Davidson E, Zhou S, Coggeshall RE (2001) Somatostatin receptors on the peripheral primary afferent terminals:inhibition of sensitized nociceptors. Pain 90:233-244
6. 2 somtatostatin receptor in the mouse retina. Naunyn Schmiedebergs Arch Pharmacol 367:188-192
7. Epelbaum J, Dournaud P, Fodor M, Viollet C (1994) The neurobiology of somatostatin. Crit Rev Neurobiol 8:25-44
8. Eschalier A, Aumaitre O, Ardid D, Fialip J, Duchene-Marullaz P (1991) Long-lasting antinociceptive effect of RC-160, a somatostatin analog, in mice and rats. Eur J Pharmacol 199:119-121
9. Hoyer D, Bell GI, Berelowitz M, Epelbaum J, Feniuk W, Humphrey PP, O'Carroll AM, Patel YC, Schonbrunn A, Taylor JE, Reisine T (1995) Classification and nomenclature of somatostatin receptors. Trends Pharmacol Sci 16:86-88
10. Ichikawa H, Schulz S, Hollt V, Sugimoto T (2003) The somatostatin sst2A receptor in the rat trigeminal ganglion. Neuroscience 120:807-813
11. Jiang N, Furue H, Katafuchi T, Yoshimura M (2003) Somatostatin directly inhibits substantia gelatinosa neurons in adult rat spinal dorsal horn in vitro. Neurosci Res 47:97-107
12. Knight Y, Bartsch T, Kaube H, Goadsby PJ (2002) P/Q-type calcium channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? J Neurosci 22:RC213
13. Matharu MS, Levy MJ, Meeran K, Goadsby PJ (2004) Subcutaneous octreotide in cluster headache: randomized placebo-controlled double-blind crossover study. Ann Neurol 56:488-494
14. Matsumoto S, Takeda M, Tanimoto T (1999) Effects of electrical stimulation of the tooth pulp and phrenic nerve fibers on C1 spinal neurons in the rat. Exp Brain Res 126:351-358
15. Matucci-Cerinic M, Borrelli F, Generini S, Cantelmo A, Marcucci I, Martelli F, Romagnoli P, Bacci S, Conz A, Marinelli P, Marabini S (1995) Somatostatin-induced modulation of inflammation in experimental arthritis. Arthritis Rheum 38(11):1687-1693
16. Nishikawa T, Takeda M, Tanimoto T, Matsumoto S (2004) Convergence of nociceptive information from temporomandibular joint and tooth pulp afferents on C1 spinal neurons in the rat. Life Sci 75(12):1465-1478
17. Oshima K, Takeda M, Tanimoto T, Katsuumi I, Matsumoto S (2005) Tooth-pulp-evoked rostral spinal trigeminal nucleus neuron activity is inhibited by conditioning sciatic nerve stimulation in the rat: possible role of 5-HT3 receptor mediated GABAergic inhibition. Brain Res Bull 65(1):31-40
18. Oshima K, Takeda M, Tanimoto T, Katsuumi I, Matsumoto S (2006) Tooth-pulp-evoked rostral spinal trigeminal neuronal excitation is attenuated by the activation of 5-HT3 receptors via GABAergic interneurons in the rat. Brain Res 1109(1):70-73
19. Patel YC (1999) Somatostatin and its receptor family. Front Neuroendocrinol 20:157-198
20. Pawlak M, Schmidt RF (2004) Octreotide, a somatostatin analogue, attenuates movement evoked discharges of fine afferent units from inflamed knee joints of rats. Neurosci Lett 361(1-3):180-183
21. Pintér E, Helyes Z, Szolcsányi J (2006) Inhibitory effect of somatostatin on inflammation and nociception. Pharmacol Ther 112:440-456
22. Randic M, Miletic V (1978) Depressant actions of methionine-enkephalin and somatostatin in cat dorsal horn neurones activated by noxious stimuli. Brain Res 152:196-202
23. Reubi JC, Waser B, Markusse HM, Krenning EP, VanHagen M, Laissue JA (1994) Vascular somatostatin receptors in synovium from patients with rheumatoid arthritis. Eur J Pharmacol 271(2-3):371-378
24. Selmer I, Schinder M, Allen JP, Humphrey PP, Emson PC (2000) Advances in understanding neuronal somatostatin receptors. Regul Pept 90:1-18
25. Takeba Y, Suzuki N, Takeno M, Asai T, Tsuboi S, Hoshino T, Sakane T (1997) Modulation of synovial cell function by somatostatin in patients with rheumatoid arthritis. Arthritis Rheum 40(12):2128-2138
26. Takeda M, Tanimoto T, Ito M, Nasu M, Matsumoto S (2005) Role of capsaicin-sensitive afferent inputs from the masseter muscle in the C1 spinal neurons responding to tooth-pulp stimulation in rats. Exp Brain Res 160:107-117
27. Takeda M, Kadoi J, Takahashi M, Nasu M, Matsumoto S (2007) Somatostatin inhibit the excitability of rat small-diameter trigeminal ganglion neurons that innervate nasal mucosa and project to the upper cervical dorsal horn via activation of somatostatin 2a receptor. Neuroscience 148(3):744-756
28. Tanimoto T, Takeda M, Matsumoto S (2002) Suppressive effect of vagal afferents on cervical dorsal horn neurons responding to tooth pulp electrical stimulation in the rat. Exp Brain Res 145(4):468-479