PI3K/AKT pathway activation in acute myeloid leukaemias is not associated with AKT1 pleckstrin homology domain mutation

British Journal of Haematology

Volumn 140, Issue 3, 2008, Pages 344-347

  Tibes, Raoul ^a   Kornblau, Steven M ^b   Qiu, Yihua ^b   Mousses, Spyro M ^a   Robbins, Christiane ^a   Moses, Tracy ^a   Carpten, John D ^a  

^a TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Acute myeloid leukaemia; Mutation; Phosphoinositide 3 kinase AKT; Protein phosphorylation; Signal transduction pathway

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOPROTEIN; PLECKSTRIN; PROTEIN KINASE B; PROTEIN S6;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BLOOD PROTEINS; DNA MUTATIONAL ANALYSIS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MUTATION; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN ARRAY ANALYSIS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TRANSLOCATION, GENETIC;

EID: 38349086652     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06920.x     Document Type: Article

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