A mechanistic study on the chemical and enzymatic degradation of PEG-Oligo(ε-caprolactone) micelles

Journal of Pharmaceutical Sciences

Volumn 97, Issue 1, 2008, Pages 506-518

  Carstens, Myrra G ^a,b   Van Nostrum, Cornelus F ^a   Verrijk, Ruud ^b   De Leede, Leo G J ^b   Crommelin, Daan J A ^a   Hennink, Wim E ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b OctoPlus NV   (Netherlands)

Author keywords

Biodegradable polymers; Enzymes; Micelle; Pegylation; Polymer biodegradation; Polymeric drug carrier; Stability

Indexed keywords

MACROGOL; METHOXYPOLY(ETHYLENE GLYCOL) OLIGO(EPSILON CAPROLACTONE); OLIGO(EPSILON CAPROLACTONE); OLIGOMER; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADABILITY; DEGRADATION; DEGRADATION KINETICS; DRUG STABILITY; ENZYME DEGRADATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICELLE; PH MEASUREMENT; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE SENSITIVITY;

EID: 38349086189     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21092     Document Type: Article

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