The t(4;8) is mediated by homologous recombination between olfactory receptor gene clusters, but other 4p16 translocations occur at random

Genetic Counseling

Volumn 18, Issue 4, 2007, Pages 357-365

  Maas, N M C ^a   Van Vooren, S ^b   Hannes, F ^a   Van Buggenhout, G ^a   Mysliwiec, M ^c   Moreau, Y ^b   Fagan, K ^d   Midro, A ^c   Engiz, O ^e   Balci, S ^e   Parker, M J ^f   Sznajer, Y ^g   Devriendt, K ^a   Fryns, J P ^a   Vermeesch, J R ^a,h  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^d JOHN HUNTER HOSPITAL   (Australia)

^e HACETTEPE UNIVERSITY   (Turkey)

^f SHEFFIELD CHILDREN S HOSPITAL   (United Kingdom)

^g HOP UNIV DES ENFANTS REINE FABIOLA   (Belgium)

^h O and N1   (Belgium)

Author keywords

Chromosome 4; Non allelic homologous recombination; Olfactory receptor gene cluster; Telomere capture; Translocation; Wolf Hirschhorn syndrome

Indexed keywords

ALLELE; ARTICLE; CHROMOSOME 4; CHROMOSOME 4P; CHROMOSOME 4P16; CHROMOSOME 8; CHROMOSOME TRANSLOCATION; DNA FLANKING REGION; FEMALE; GENE CLUSTER; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC RECOMBINATION; HOMOLOGOUS RECOMBINATION; HUMAN; MALE; OLFACTORY RECEPTOR; SEQUENCE HOMOLOGY;

ADULT; CHROMOSOMES, HUMAN, PAIR 4; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; MALE; MULTIGENE FAMILY; PHENOTYPE; RECEPTORS, ODORANT; TELOMERE; TRANSLOCATION, GENETIC; WOLF-HIRSCHHORN SYNDROME;

EID: 38349081701     PISSN: 10158146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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