Induction of type I interferons and interferon-inducible Mx genes during respiratory syncytial virus infection and reinfection in cotton rats

Journal of General Virology

Volumn 89, Issue 1, 2008, Pages 261-270

  Pletneva, Lioubov M ^a   Haller, Otto ^b   Porter, David D ^a   Prince, Gregory A ^a   Blanco, Jorge C G ^a  

^a Virion Systems Inc   (United States)

^b UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; MESSENGER RNA; MYXOVIRUS RESISTANCE PROTEIN;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COTTON RAT; CYTOKINE PRODUCTION; DISEASE MARKER; GENE EXPRESSION; GENE INDUCTION; GENE LOCATION; IMMUNOMODULATION; IN VIVO STUDY; INNATE IMMUNITY; LUNG; NONHUMAN; NOSE; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; REINFECTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SPLEEN; VIRUS GENE; VIRUS INFECTION; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; INTERFERON TYPE I; LUNG; ORGAN SPECIFICITY; RECURRENCE; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGMODONTINAE; VIRUS REPLICATION;

ANIMALIA; RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS; SIGMODON;

EID: 38349079836     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83294-0     Document Type: Article

References (44)

1. Blanco, J. C., Richardson, J. Y., Darnell, M. E., Rowzee, A., Pletneva, L., Porter, D. D. & Prince, G. A. (2002). Cytokine and chemokine gene expression after primary and secondary respiratory syncytial virus infection in cotton rats. J Infect Dis 185, 1780-1785.
2. Bossert, B., Marozin, S. & Conzelmann, K. K. (2003). Nonstructural proteins NS1 and NS2 of bovine respiratory syncytial virus block activation of interferon regulatory factor 3. J Virol 77, 8661-8668.
3. Boukhvalova, M. S., Prince, G. A., Soroush, L., Harrigan, D. C., Vogel, S. N. & Blanco, J. C. (2006). The TLR4 agonist, monophosphoryl lipid A, attenuates the cytokine storm associated with respiratory syncytial virus vaccine-enhanced disease. Vaccine 24, 5027-5035.
4. Boukhvalova, M. S., Prince, G. A. & Blanco, J. C. G. (2007). Respiratory syncytial virus infects and abortively replicates in the lungs in spite of pre-existing immunity. J Virol 81, 9443-9450.
5. Bracci, L., Canini, I., Venditti, M., Spada, M., Puzelli, S., Donatelli, I., Belardelli, F. & Proietti, E. (2006). Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus. Vaccine 24 (Suppl. 2), S56-S57.
6. Chonmaitree, T., Roberts, N. J., Jr, Douglas, R. G., Jr, Hall, C. B. & Simons, R. L. (1981). Interferon production by human mononuclear leukocytes: differences between respiratory syncytial virus and influenza viruses. Infect Immun 32, 300-303.
7. Diaz, M. O., Pomykala, H. M., Bohlander, S. K., Maltepe, E., Malik, K., Brownstein, B. & Olopade, O. I. (1994). Structure of the human type-I interferon gene cluster determined from a YAC clone contig. Genomics 22, 540-552.
8. Durbin, J. E., Johnson, T. R., Durbin, R. K., Mertz, S. E., Morotti, R. A., Peebles, R. S. & Graham, B. S. (2002). The role of IFN in respiratory syncytial virus pathogenesis. J Immunol 168, 2944-2952.
9. Falsey, A. R., Hennessey, P. A., Formica, M. A., Cox, C. & Walsh, E. E. (2005). Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med 352, 1749-1759.
10. Flohr, F., Schneider-Schaulies, S., Haller, O. & Kochs, G. (1999). The central interactive region of human Mx-A GTPase is involved in GTPase activation and interaction with viral target structures. FEBS Lett 463, 24-28.
11. Forster, J., Schweizer, M., Schumacher, R. F., Kaufmehl, K. & Lob, S. (1996). MxA protein in infants and children with respiratory tract infection. Acta Paediatr 85, 163-167.
12. Garofalo, R., Mei, F., Espejo, R., Ye, G., Haeberle, H., Baron, S., Ogra, P. L. & Reyes, V. E. (1996). Respiratory syncytial virus infection of human respiratory epithelial cells up-regulates class I MHC expression through the induction of IFN-β and IL-1α. J Immunol 157, 2506-2513.
13. Guerrero-Plata, A., Casola, A., Suarez, G., Yu, X., Spetch, L., Peeples, M. E. & Garofalo, R. P. (2006). Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. Am J Respir Cell Mol Biol 34, 320-329.
14. Hall, C. B., Douglas, R. G., Jr, Simons, R. L. & Geiman, J. M. (1978). Interferon production in children with respiratory syncytial, influenza, and parainfluenza virus infections. J Pediatr 93, 28-32.
15. Hall, C. B., Douglas, R. G., Jr & Simons, R. L. (1981). Interferon production in adults with respiratory syncytial viral infection. Ann Intern Med 94, 53-55.
16. Halminen, M., Ilonen, J., Julkunen, I., Ruuskanen, O., Simell, O. & Makela, M. J. (1997). Expression of MxA protein in blood lymphocytes discriminates between viral and bacterial infections in febrile children. Pediatr Res 41, 647-650.
17. Henderson, F. W., Collier, A. M., Clyde, W. A., Jr & Denny, F. W. (1979). Respiratory - syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children. N Engl J Med 300, 530-534.
18. Hiscott, J., Cantell, K. & Weissmann, C. (1984). Differential expression of human interferon genes. Nucleic Acids Res 12, 3727-3746.
19. Holzinger, D., Jorns, C., Stertz, S., Boisson-Dupuis, S., Thimme, R., Weidmann, M., Casanova, J.-L., Haller, O. & Kochs, G. (2007). Induction of MxA gene expression by influenza A virus requires type I or type III interferon signaling. J Virol 81, 7776-7785.
20. Hornung, V., Schlender, J., Guenthner-Biller, M., Rothenfusser, S., Endres, S., Conzelmann, K. K. & Hartmann, G. (2004). Replication-dependent potent IFN-χ induction in human plasmacytoid dendritic cells by a single-stranded RNA virus. J Immunol 173, 5935-5943.
21. Isaacs, D. (1989). Production of interferon in respiratory syncytial virus bronchiolitis. Arch Dis Child 64, 92-95.
22. Jamaluddin, M., Wang, S., Garofalo, R. P., Elliott, T., Casola, A., Baron, S. & Brasier, A. R. (2001). IFN-β mediates coordinate expression of antigen-processing genes in RSV-infected pulmonary epithelial cells. Am J Physiol Lung Cell Mol Physiol 280, L248-L257.
23. McIntosh, K. (1978). Interferon in nasal secretions from infants with viral respiratory tract infections. J Pediatr 93, 33-36.
24. Nakayama, T., Sonoda, S., Urano, T., Sasaki, K., Maehara, N. & Makino, S. (1993). Detection of alpha-interferon in nasopharyngeal secretions and sera in children infected with respiratory syncytial virus. Pediatr Infect Dis J 12, 925-929.
25. Pletneva, L. M., Haller, O., Porter, D. D., Prince, G. A. & Blanco, J. C. (2006). Interferon-inducible Mx gene expression in cotton rats: cloning, characterization, and expression during influenza viral infection. J Interferon Cytokine Res 26, 914-921.
26. Prince, G. A., Jenson, A. B., Horswood, R. L., Camargo, E. & Chanock, R. M. (1978). The pathogenesis of respiratory syncytial virus infection in cotton rats. Am J Pathol 93, 771-791.
27. Prince, G. A., Prieels, J. P., Slaoui, M. & Porter, D. D. (1999). Pulmonary lesions in primary respiratory syncytial virus infection, reinfection, and vaccine-enhanced disease in the cotton rat (Sigmodon hispidus). Lab Invest 79, 1385-1392.
28. Prince, G. A., Mond, J. J., Porter, D. D., Yim, K. C., Lan, S. J. & Klinman, D. M. (2003). Immunoprotective activity and safety of a respiratory syncytial virus vaccine: mucosal delivery of fusion glycoprotein with a CpG oligodeoxynucleoticle adjuvant. J Virol 77, 13156-13160.
29. Richter, B. W., Onuska, J. M., Niewiesk, S., Prince, G. A. & Eichelberger, M. C. (2005). Antigen-dependent proliferation and cytokine induction in respiratory syncytial virus-infected cotton rats reflect the presence of effector-memory T cells. Virology 337, 102-110.
30. Roberts, N. J., Jr, Hiscott, J. & Signs, D. J. (1992). The limited role of the human interferon system response to respiratory syncytial virus challenge: analysis and comparison to influenza virus challenge. Microb Pathog 12, 409-414.
31. Roers, A., Hochkeppel, H. K., Horisberger, M. A., Hovanessian, A. & Haller, O. (1994). MxA gene expression after live virus vaccination: a sensitive marker for endogenous type I interferon. J Infect Dis 169, 807-813.
32. Schlender, J., Homung, V., Finke, S., Gunthner-Biller, M., Marozin, S., Brzozka, K., Moghim, S., Endres, S., Hartmann, G. & Conzelmann, K. K. (2005). Inhibition of Toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus. J Virol 79, 5507-5515.
33. Seya, T., Akazawa, T., Tsujita, T. & Matsumoto, M. (2006). Role of Toll-like receptors in adjuvant-augmented immune therapies. Evid Based Complement Alternat Med 3, 31-38.
34. Simon, A., Fah, J., Haller, O. & Staeheli, P. (1991). Interferon-regulated Mx genes are not responsive to interleukin-1, tumor necrosis factor, and other cytokines. J Virol 65, 968-971.
35. Smith, P. L., Lombardi, G. & Foster, G. R. (2005). Type I interferons and the innate immune response - more than just antiviral cytokines. Mol Immunol 42, 869-877.
36. Spann, K. M., Tran, K. C., Chi, B., Rabin, R. L. & Collins, P. L. (2004). Suppression of the induction of alpha, beta, and lambda interferons by the NSI and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages. J Virol 78, 4363-4369.
37. Stark, G. R., Kerr, I. M., Williams, B. R., Silverman, R. H. & Schreiber, R. D. (1998). How cells respond to interferons. Annu Rev Biochem 67, 227-264.
38. Stertz, S., Dittmann, J., Blanco, J. C. G., Pletneva, L. M., Haller, O. & Kochs, G. (2007). Tile antiviral potential of interferon-induced cotton rat Mx proteins against orthomyxo- (influenza), rhabdo- and bunyaviruses. J Interferon Cytokine Res 27, 847-856.
39. Taylor, C. E., Webb, M. S., Milner, A. D., Milner, P. D., Morgan, L. A., Scott, R., Stokes, G. M., Swarbrick, A. S. & Toms, G. L. (1989). Interferon alfa, infectious virus, and virus antigen secretion in respiratory syncytial virus infections of graded severity. Arch Dis Child 64, 1656-1660.
40. Theofilopoulos, A. N., Baccala, R., Beutler, B. & Kono, D. H. (2005). Type I interferons (χ/β) in immunity and autoimmunity. Annu Rev Immunol 23, 307-336.
41. Thompson, W. W., Shay, D. K., Weintraub, E., Brammer, L., Cox, N., Anderson, L. J. & Fukuda, K. (2003). Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 289, 179-186.
42. Tovey, M. G., Lallemand, C., Meritet, J. F. & Maury, C. (2006). Adjuvant activity of interferon alpha: mechanism (s) of action. Vaccine 24 (Suppl. 2), S46-S47.
43. Wang, H., Peters, N, & Schwarze, J. (2006). Plasmacytoid dendritic cells limit viral replication, pulmonary inflammation, and airway hyperresponsiveness in respiratory syncytial virus infection. J Immunol 177, 6263-6270.
44. Welliver, R. C. (2003). Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infection. J Pediatr 143, S112-S117.