IFN-β mediates coordinate expression of antigen-processing genes in RSV-infected pulmonary epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 280, Issue 2 24-2, 2001, Pages

  Jamaluddin, Mohammad ^a   Wang, Shaofei ^a   Garofalo, Roberto P ^a   Elliott, Todd ^a   Casola, Antonella ^a   Baron, Samuel ^a   Brasier, Allan R ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

26S proteasome; ABC transporter; Interferon ; Major histocompatibility complex class II locus; Pulmonary inflammation; Respiratory syncytial virus

Indexed keywords

ABC TRANSPORTER; CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; PROTEASOME; RECOMBINANT BETA INTERFERON; RECOMBINANT INTERLEUKIN 1ALPHA;

ANTIGEN PRESENTATION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFECTION; VIRUS INFECTION;

EID: 0035009446     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.2.l248     Document Type: Article

References (53)

1. Ahn K, Meyer TH, Uebel S, Sempe P, Djaballah H, Yang Y, Peterson PA, Fruh K, and Tampe R. Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus protein ICP47. EMBO J 15: 3247-3255, 1996.
2. Androlewicz MJ, Anderson KS, and Cresswell P. Evidence that transporters associated with antigen-processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc Natl Acad Sci USA 90: 9130-9134, 1993.
3. Arnold D, Driscoll J, Androlewicz MJ, Hughes E, Cresswell P, and Spies T. Proteasome subunits encoded in the MHC are not generally required for the processing of peptides bound by MHC class I molecules. Nature 360: 171-174, 1992.
4. Arnold R, Humbert B, Werchaus H, Gallati H, and Konig W. Interleukin-8, interleukin-6, and soluble tumor necrosis factor receptor type I released from a human pulmonary epithelial cell line (A549) exposed to respiratory syncytial virus. Immunology 82: 126-133, 1994.
5. Beck S, Abdullah S, Alderton RP, Glynne RJ, Gut IG, Hosking LK, Jackson A, Kelly A, Newell WR, Sanseau P, Radley E, Thorpe KL, and Trowsdale J. Evolutionary dynamics of non-coding sequences within the class II region of the human MHC. J Mol Biol 255: 1-13, 1996.
6. Beck S, Kelly A, Radley E, Khurshid F, Alderton RP, and Trowsdale J. DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing. J Mol Biol 228: 433-441, 1992.
7. Brasier AR, Jamaluddin M, Casola A, Duan W, Shen Q, and Garofalo R. A promoter recruitment mechanism for TNFα-induced IL-8 transcription in type II pulmonary epithelial cells: dependence on nuclear abundance of Rel A, NF-kB1 and c-Rel transcription factors. J Biol Chem 273: 3551-3561, 1998.
8. Canon MJ, Openshaw PJM, and Askonas BA. Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus. J Exp Med 168: 1163-1168, 1988.
9. Collins PL, McIntosh K, and Chanock RM. Respiratory syncytial virus. In: Fields Virology, edited by Fields BN and Knipe DM. Philadelphia, PA: Raven, 1996, p. 1313-1351.
10. Cresswell P, Androlewicz MJ, and Ortman B. Assembly and transport of class I MHC-peptide complexes. Ciba Found Symp 187: 150-162, 1994.
11. Deverson EV, Gow IR, Coadwell WJ, Monaco JJ, Butcher GW, and Howard JC. MHC class II region encoding proteins related to multidrug resistance family of transmembrane transporters. Nature 348: 738-741, 1990.
12. Driscoll J, Brown MG, Finley D, and Monaco JJ. MHC-linked LMP gene products specifically alter peptidase activities of the proteasome. Nature 365: 262-264, 1993.
13. Elliott T. Transporter associated with antigen processing. Adv Immunol 65: 47-109, 1997.
14. Fehling HJ, Swat W, Laplace C, Kuhn R, Rajewsky K, Muller U, and Boehmer HV. MHC class I expression in mice lacking the proteasome subunit LMP-7. Science 265: 1234-1237, 1994.
15. Fenteany G, Standaert RF, Lane WS, Choi S, Corey EJ, and Schreiber SL. Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin. Science 268: 726-731, 1995.
16. Gaczynska M, Goldberg AL, Tanaka K, Hendil K, and Rock KL. Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-γ-induced subunits LMP2 and LMP7. J Biol Chem 271: 17275-17280, 1996.
17. Gaczynska M, Rock KL, and Goldberg AL. γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasome. Nature 365: 264-267, 1993.
18. Gaczynska M, Rock KL, Spies T, and Goldberg AL. Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes LMP2 and LMP7. Proc Natl Acad Sci USA 91: 9213-9217, 1994.
19. Garofalo R, Mei F, Espejo R, Ye G, Haeberle H, Baron S, Ogra PL, and Reyes VE. Respiratory syncytial virus infection of human respiratory epithelial cells up-regulates class I MHC expression through the induction of IFN-β and IL-1α. J Immunol 157: 2506-2513, 1996.
20. Garofalo R and Ogra PL. Mechanisms of mucosal immunopathology in respiratory syncytial virus infection. In: Essentials of Mucosal Immunology, edited by Kagnoff M and Kiyono H. San Diego, CA: Academic, 1996.
21. Garofalo R, Sabry M, Jamaluddin M, Yu RK, Casola A, Ogra PL, and Brasier AR. Transcriptional activation of the interleukin-8 gene by RSV infection in alveolar epithelial cells: nuclear translocation of the Rel A transcription factor as a mechanism producing airway mucosal inflammation. J Virol 70: 8773-8781, 1996.
22. Gatfield J, Lammert E, Nickolaus P, Munz C, Rothenfusser S, Fisch P, Stevanovic S, Schild H, Rammensee H-G, and Arnold D. Cell lines transfected with the TAP inhibitor ICP47 allow testing peptide binding to a variety of class I molecules. Int Immunol 10: 1665-1672, 1998.
23. Graham BS, Bunton LA, Wright PF, and Karzon DT. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory virus in mice. J Clin Invest 88: 1026-1033, 1991.
24. Hall CB. Respiratory syncytial virus. In: Textbook of Pediatric Infectious Disease, edited by Feigin D and Cherry JD. Philadelphia. PA: Saunders, 1992, p. 1633-1656.
25. Han Y, Weinmann S, Boldogh I, Walker RK, and Brasier AR. Tumor necrosis factor-α-inducible IκB proteolysis mediated by cytosolic m-calpain: a mechanism parallel to the ubiquitin-proteasome pathway for nuclear factor-κB activation. J Biol Chem 274: 787-794, 1999.
26. Heemels MT and Ploegh HD. Generation, translocation, and presentation of class I-restricted peptides. Annu Rev Biochem 64: 463-491, 1995.
27. Hill A, Jugovic P, York IA, Russ G, Bennink J, Yewdell J, Ploegh HD, and Johnson DC. Herpes simplex virus turns off the TAP to evade host immunity. Nature 375: 411-415, 1995.
28. Jamaluddin M, Casola A, Garofalo RP, Han Y, Elliott T, Ogra PL, and Brasier AR. The major component of IκBα proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cells. J Virol 72: 4849-4857, 1998.
29. Jamaluddin M, Garofalo R, Ogra PL, and Brasier AR. Inducible translational regulation of the NF-IL6 transcription factor by respiratory syncytial virus infection in pulmonary epithelial cells. J Virol 70: 1554-1563, 1996.
30. Kaer LV, Ashton-Rickardt PG, Ploegh HD, and Tonegawa S. TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells. Cell 71: 1205-1214, 1992.
31. Kim HW, Canchola JG, and Brandt CD. Respiratory syncytial virus disease infants despite prior administration of antigenic inactivated vaccine. Am J Epidemiol 89: 422-434, 1969.
32. Lieber M, Smith B, Szakal A, Nelson-Rees W, and Todaro G. A continuous tumor-cell line from a human lung carcinoma with properties of type II alveolar epithelial cells. Int J Cancer 17: 62-70, 1976.
33. Milner ME, Monte SDL, and Hutchins GM. Fatal respiratory syncytial virus infection in severe combined immunodeficiency syndrome. Am J Dis Child 139: 1111-1114, 1985.
34. Momberg F, Ortiz-Navarrete V, Neefjes JJ, Goulmy E, Wal VDY, Spits H, Powis SJ, Butcher GW, Howard JC, Walden P, and Hämmerling GJ. Proteasome subunits encoded by the major histocompatibility complex are not essential for antigen processing. Nature 360: 174-177, 1992.
35. Monaco JJ, Cho S, and Attya M. Transport protein genes in the murine MHC: possible implications for antigen processing. Science 250: 1723-1726, 1990.
36. Neefjes JJ, Momberg F, and Hämmerling GJ. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 261: 769-771, 1993.
37. Noah TL and Becker S. Respiratory syncytial virus-induced cytokine production by a human bronchial epithelial cell line. Am J Physiol Lung Cell Mol Physiol 265: L472-L478, 1993.
38. Openshaw PJM. Immunopathological mechanisms in respiratory syncytial virus disease. Springer Semin Immunopathol 17: 187-201, 1995.
39. Patel JA, Kunimoto M, Sim TC, Garofalo R, Eliott T, Baron S, Ruuskanen O, Chonmaitree T, Ogra PL, and Schmalstieg FCJ. IL-1α mediates enhanced expression of ICAM-1 in pulmonary epithelial cells infected with respiratory syncytial virus. Am J Respir Cell Mol Biol 13: 602-609, 1995.
40. Reyes VE, Klimpel KD, and Kumpel GR. T cell regulation of interferon-alpha/beta (IFN-alpha/beta) production by alloantigen-stimulated bone marrow cells. J Immunol 134: 3137-3141, 1985.
41. Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, and Goldberg AL. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78: 761-771, 1994.
42. Ruuskanen O and Ogra PL. Respiratory syncytial virus. Curr Probl Pediatr 2: 50-79, 1993.
43. Spies T, Bresnahan M, Bahram S, Arnold D, Blanck G, Mellins E, Pious D, and DeMars R. A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway. Nature 348: 744-747, 1990.
44. Steinhoff U, Muller U, Schertler A, Hengartner H, Aguet M, and Zinkernagel RM. Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice. J Virol 69: 2153-2158, 1995.
45. Tomazin R, Hill AB, Jugovic P, York IA, van Endert PM, Ploegh HD, Andrews DW, and Johnson DC. Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP. EMBO J 15: 3256-3266, 1996.
46. Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, and Kelly A. Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters. Nature 348: 741-744, 1990.
47. Van Kaer L, Ashton-Rickardt PG, Eichelberger M, Gaczynska M, Nagashima K, Rock KL, Goldberg AL, Doherty PC, and Tonegawa S. Altered peptidase and viral-specific T cell response in LMP2 mutant mice. Immunity 1: 533-541, 1994.
48. Virca GD, Northemann W, Shiels BR, Widera G, and Broome S. Simplified Northern blot hybridization using 5% sodium dodecyl sulfate. Biotechniques 8: 370-371, 1990.
49. Vlahopoulos S, Boldogh I, Casola A, and Brasier AR. Nuclear factor-κB-dependent induction of interleukin-8 gene by tumor necrosis factor-α: evidence for an antioxidant sensitive activating pathway distinct from nuclear translocation. Blood 94: 1878-1889, 1999.
50. Welliver RC, Kaul A, and Ogra PL. Cell-mediated immune response to respiratory syncytial virus infection: relationship to the development of reactive airway disease. J Pediatr 94: 370-375, 1979.
51. Welliver RC, Wong DT, Sun M, Middleton E Jr, Vaughan RS, and Ogra PL. The development of respiratory syncytial virus-specific IGE and the release of histamine in nasopharyngeal secretions after infection. N Engl J Med 305: 841-846, 1981.
52. Wright KL, White LC, Kelly A, Beck S, Trowsdale J, and Ting JPY. Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter. J Exp Med 181: 1459-1471, 1995.
53. + T lymphocytes. Cell 77: 525-535, 1994.