GABAB receptors are required for galanin modulation of membrane properties of neurons in the arcuate nucleus of rats

Brain Research

Volumn 1191, Issue , 2008, Pages 63-68

  Tyszkiewicz, Joanna P ^a   Fong, Tung M ^a   Dong, Yan ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Arcuate nucleus; Electrophysiology; Excitability; Galanin

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; CALCIUM; GALANIN; GALANIN RECEPTOR;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; MEMBRANE STEADY POTENTIAL; NERVE MEMBRANE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; CELL MEMBRANE POTENTIAL; CYTOLOGY; FEMALE; IN VITRO STUDY; MALE; METABOLISM; NERVE CELL; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ARCUATE NUCLEUS; CALCIUM; FEMALE; GALANIN; MALE; MEMBRANE POTENTIALS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-B; RECEPTORS, GALANIN;

EID: 38349073313     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.11.032     Document Type: Article

References (28)

1. Bedecs K., Berthold M., and Bartfai T. Galanin-10 years with a neuroendocrine peptide. Int. J. Biochem. Cell Biol. 27 (1995) 337-349
2. Bettler B., Kaupmann K., Mosbacher J., and Gassmann M. Lomecular structure and physiological functions of GABA(B) receptors. Physiol. Rev. 84 (2004) 835-867
3. Bonnefond C., Lalacios J.M., Probst A., and Mengod G. Distribution of galanin mRNA containing cells and galanin receptor binding sites in human and rat hypothalamus. Eur. J. Neurosci. 2 (1990) 629-637
4. Branchek T.B., Smith K.E., Gerald C., and Walker M.W. Galanin receptor subtypes. TIPS 21 (2000) 109-117
5. Crawley J.N. The role of galanin in feeding behavior. Neuropeptides 33 (1999) 369-375
6. Dong Y., Tyszkiewicz J.P., and Fong T.M. Galanin and galanin-like peptide differentially modulate neuronal activities in rat arcuate nucleus neurons. J. Neurophysiol. 95 (2006) 3228-3234
7. Fathi Z., Battaglino P.M., Iben L.G., Baker E., Zhand D., McGovern R., Mahle C.D., Sutherland G.R., Iismaa T.P., Dickinson K.E., and Zimanyi I.A. Molecular characterization, pharmacological properties and chromosomal localization of the human GAL2R galanin receptor. Brain. Res. Mol. Brain. Res. 58 (1998) 156-169
8. Floren A., Land T., and Langel U. Galanin receptor subtypes and ligand binding. Neuropeptide 34 11 (2000) 331-337
9. Fong T.M., and Van der Ploeg L.H. A melanocortin agonist reduces neuronal firing rate in rat hypothalamic slices. Neurosci. Lett. 283 (2000) 5-8
10. Glaum S.R., Hara M., Biondokas V.P., Lee C.C., Polonsky K.S., Bell G.I., and Miller R.J. Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus. Mol. Pharmacol. 50 (1996) 230-235
11. Habert-Ortoli E., Amiranoff B., Loquet I., Laburthe M., and Mayaux J.F. Molecular cloning of a functional human galanin receptor. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 9780-9783
12. Hokfelt T. Galanin and its receptors: introduction to the Third International Symposium, San Diego, California, USA, 21-22 October 2004. Neuropeptides 39 (2004) 125-142
13. Huang Z.J. GABAB receptor isoforms caught in action at the scene. Neuron 50 (2006) 521-524
14. Jobst E.E., Enriori P.J., and Cowley M.A. The electrophysiology of feeding circuits. Trends Endocrinol. Metab. 15 (2004) 488-499
15. Kalra S.P., Dube M.G., Pu S., Xu B., Horvath T.L., and Kalra P.S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 20 (1999) 68-100
16. Kamatchi G.L., and Ticku M.K. Functional coupling of presynaptic GABAB receptors with voltage-gated Ca2+ channels: regulation by protein kinase A and C in cultured spinal cord neurons. Mol. Pharmacol. 38 (1990) 342-347
17. Kaupmann K., Huggel K., Heid J., Flor P.J., Bischoff S., Mickel S.J., McMaster G., Angst C., Bittiger H., Froestl W., and Bettler B. Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors. Nature 386 (1997) 223-224
18. Kinght A.R., and Bowery N.G. The pharmacology of adenylyl cyclase modulation by GABAB receptors in rat brain slices. Neuropharmacology 35 (1996) 703-712
19. Kinney G.A., Emmerson P.J., and Miller R.J. Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus. J. Neurosci. 18 (1998) 3489-3500
20. Merchenthaler I., Lopez F.J., and Negro-Vilar A. Anatomy and physiology of central galanin-containing pathways. Prog. Neurobiol. 40 (1993) 711-769
21. Misgeld U., Bijak M., and Jarolimek W. A physiological role for GABAB receptors and the effects of baclofen in the mammalian central nervous system. Prog. Neurobiol. 46 (1995) 423-462
22. Nicoll R.A. My close encounter with GABAB receptors. Biochem. Pharmacol. 68 (2004) 1667-1674
23. Nordstrom O., Melander T., Hokfelt T., Bartfai T., and Goldstein M. Evidence for an inhibitory effect of the peptide galanin on dopamine release from the rat median eminence. Neurosci. Lett. 73 (1987) 21-26
24. Rocheville M., Lange D.C., Kumar U., Patel S.C., Patel R.C., and Patel Y.C. Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity. Science 288 (2000) 154-157
25. Salim K., Fenton T., Bacha J., Urien-Rodriguez H., Bonnert T., Skynner H.A., Watts E., Kerby J., Heald A., Beer M., McAllister G., and Guest P.C. Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation. J. Biol. Chem. 277 (2002) 15482-15485
26. Smith K.E., Forray C., Walker M.W., Jones K.A., Tamm J.A., Bard J., Branchek T.A., Linemeyer D.L., and Gerlad C. Expression cloning of rat hypothalamic galanin receptor coupled to phosphoinositide turnover. J. Biol. Chem. 272 (1997) 241612-241616
27. Stanely S., Wynne K., McGowan B., and Bloom S. Hormonal regulation of food intake. Physiol. Rev. 85 (2005) 1131-1158
28. Zini S., Roisin M.P., Langel U., Bartfai T., and Ben-Ari Y. Galanin reduces release of endogenous excitatory amino acids in the rat hippocampus. Eur. J. Pharmacol. 245 (1993) 1-7