IFCC Guideline for sampling, measuring and reporting ionized magnesium in plasma

Clinical Chemistry and Laboratory Medicine

Volumn 46, Issue 1, 2008, Pages 21-26

  Ben Rayana, Mohammed C ^a   Burnett, Robert W ^b   Covington, Arthur K ^c   D'Orazio, Paul ^d   Fogh Andersen, Niels ^e   Jacobs, Ellis ^f   Külpmann, Wolf R ^g   Kuwa, Katsuhiko ^h   Larsson, Lasse ⁱ   Lewenstam, Andrzej ^j   Maas, Anton H J ^k   Mager, Gerhard ^l   Naskalski, Jerzy W ^m   Okorodudu, Anthony O ⁿ   Ritter, Christoph ^o   St John, Andrew ^p  

^a Institut National de Nutrition Tunis   (Tunisia)

^b HARTFORD HOSPITAL   (United States)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d INOVA DIAGNOSTICS INC   (United States)

^e GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^f WADSWORTH CENTER   (United States)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h UNIVERSITY OF TSUKUBA   (Japan)

ⁱ LINKÖPING UNIVERSITY   (Sweden)

^j ÅBO AKADEMI UNIVERSITY   (Finland)

^k EUROTRANSPLANT INTERNATIONAL FOUNDATION   (Netherlands)

^l FRESENIUS MEDICAL CARE   (Germany)

^m JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

ⁿ John Sealy Hospital and John Sealy Annex   (United States)

^o ROCHE DIAGNOSTICS GMBH   (Austria)

^p Australian Government Australian Research Council   (Australia)

more..

Author keywords

Erythrocyte effect; Heparin; Influence factors; Interference; Ion selective electrode; Ionized calcium; Ionized magnesium; Lipophilic anions; Liquid junction potential; pH; Protein; Sampling; Silicone; Sodium

Indexed keywords

ALBUMIN; CALCIUM CHLORIDE; CALCIUM ION; MAGNESIUM; MAGNESIUM ION; PROTEIN; SILICONE; SODIUM; SURFACTANT;

BINDING SITE; BIOLOGICAL ACTIVITY; BLOOD GAS ANALYSIS; CONFERENCE PAPER; DIAGNOSTIC PROCEDURE; ERYTHROCYTE; HUMAN; ION SELECTIVE ELECTRODE; IONIC STRENGTH; IONIZATION; LIPOPHILICITY; MAGNESIUM BLOOD LEVEL; OSMOLALITY; PH MEASUREMENT; PLASMA VOLUME; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROTEIN BINDING; TEMPERATURE SENSITIVITY;

BLOOD CHEMICAL ANALYSIS; BLOOD GAS ANALYSIS; CALCIUM; CALIBRATION; ELECTROLYTES; ERYTHROCYTES; GUIDELINES AS TOPIC; HUMANS; HYDROGEN-ION CONCENTRATION; ION-SELECTIVE ELECTRODES; MAGNESIUM; POINT-OF-CARE SYSTEMS; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SODIUM;

EID: 38349008591     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/CCLM.2008.001     Document Type: Conference Paper

References (43)

1. Burnett RW, Christiansen T, Covington AK, Fogh-Andersen N, Külpmann WR, Lewenstam A, et al. IFCC recommended reference method for the determination of the substance concentration of ionized calcium in undiluted serum, plasma or whole blood. Clin Chem Lab Med 2000;38:1301-14.
2. Arieff AI, DeFronzo RA, editors. Fluid, electrolyte and acid-base disorders. Churchill Livingstone: New York, 1995.
3. Altura BT, Altura BM. A method for distinguishing ionized, complexed and protein-bound Mg in normal and diseased subjects. Clin Lab Invest 1994;54(Suppl 217):83-7.
4. Huijgen HJ, Sanders R, Cecco SA, Rehak NN, Sanders GT, Elin RJ. Serum ionized magnesium: comparison of results obtained with three ion-selective analyzers. Clin Chem Lab Med 1999;37:465-70.
5. Kroll MH, Elin RJ. Relationships between magnesium and protein concentrations in serum. Clin Chem 1985;31:244-6.
6. Huijgen HJ, van Ingen HE, Kok WT, Sanders GT. Magnesium fractions in serum of healthy individuals and CAPD patients, measured by an ion-selective electrode and ultrafiltration. Clin Biochem 1996;29:261-6.
7. Altura BM, Lewenstam A, editors. Unique magnesium-sensitive ion selective electrodes. Scand J Clin Lab Invest 1994;54(Suppl 217).
8. Burnett RW, Covington AK, Fogh-Andersen N, Külpmann WR, Lewenstam A, Maas AH, et al. Use of ion-selective electrodes for blood-electrolyte analysis. Recommendations for nomenclature, definitions and conventions. Clin Chem Lab Med 2000;38:363-70.
9. Filos D, Okorodudu AO. A method for the measurement of ionized magnesium. Lab Med 1995;26:70-4.
10. Saris N-E, Mervaala E, Karppanen E, Khawaja JA, Lewenstam A. Magnesium - an update on physiological, pathological and analytical aspects. Clin Chim Acta 2000;294:1-26.
11. 2+. Scand J Clin Lab Invest 1994;54(Suppl 217):37-43.
12. Külpmann WR, Röszler J, Brunkhorst R, Schüler A. Ionized and total magnesium serum concentrations in renal and hepatic diseases. Eur J Clin Chem Clin Biochem 1996;34:257-64.
13. Külpmann WR, Rademacher E, Bornscheuer A. Ionized magnesium concentrations during liver transplantation, resection of the liver and cardiac surgery. Scand J Clin Lab Invest 1996;56(Suppl 224):235-43.
14. Marsoner HJ, Spichiger UE, Ritter Ch, Sachs Ch, Ghahramani M, Offenbacher H, et al. Measurement of ionized magnesium with neutral carrier based ISEs. Progress and results with the AVL 988-4 magnesium analyser. Scand J Clin Lab Invest 1994;54(Suppl 217):45-51.
15. Van Ingen HE, Huijgen HJ, Kok WT, Sanders GT. Analytical evaluation of KONE Microlyte determination of ionized magnesium. Clin Chem 1994;40:52-5.
16. Lyon ME, Bremner D, Laha T, Malik S, Henderson PJ, Kenny MA. Specific heparin preparations interfere with the simultaneous measurement of ionized magnesium and ionized calcium. Clin Biochem 1995:28:79-84.
17. Boink AB, Buckley BM, Christiansen TF, Covington AK, Fogh-Andersen N, Maas AH, et al. IFCC recommendation on sampling, transport and storage for the determination of the concentration of ionized calcium in whole blood, plasma and serum. J Autom Chem 1991;13:235-39,
18. Eur J Clin Chem Clin Biochem 1991;29:767-72,
19. Clin Chim Acta 1991;202:13-22,
20. Ann Biol Clin 1991;49:434-8,
21. J Int Fed Clin Chem 1992;4:147-52,
22. Acta Biochim Latinoam 1992;26:461-7.
23. Burnett RW, Covington AK, Fogh-Andersen N, Külpmann WR, Maas AH, Müller-Plathe O, et al. Approved IFCC recommendations on whole blood sampling, transport and storage for simultaneous determination of pH, blood gases and electrolytes. Eur J Clin Chem Clin Biochem 1995;33:247-53.
24. Ising H, Bertschat F, Gunther T, Jeremias E, Jeremias A. Measurement of free magnesium in blood, serum and plasma with an ion-selective electrode. Eur J Clin Chem Clin Biochem 1995;33:365-71.
25. Rouilly M, Rusterholz B, Spichiger UE, Simon W. Neutral ionophore-based selective electrode for assaying the activity of magnesium in undiluted blood serum. Clin Chem 1990;36:466-9.
26. Sokalski T, Lewenstam A. Application of Nernst-Planck and Poisson equations for interpretation of liquid-junction and membrane potentials in real-time and space domains. Electrochem Commun 2001;3:107-12.
27. Sokalski T, Lingenfelter P, Lewenstam A. Numerical solution of the coupled Nernst-Planck and Poisson equations for liquid-junction and ion-selective membrane potentials. J Phys Chem B 2003;107:2443-52.
28. Bard AJ, Faulkner LR. Electrochemical methods. New York: John Wiley & Sons, 2001.
29. Siggaard-Andersen O, Fogh-Andersen N. The erythrocyte effect on the liquid junction potential: an osmotic dilution phenomenon. In: Maas AH, Buckley B, Manzoni A, Moran RF, Siggaard-Andersen O, Sprokholt R, editors. Methodology and clinical applications of ion selective electrodes. IFCC Workshop, Stresa 1988. Utrecht: Elinkwijk, 1989:335-41.
30. Maj-Zurawska M, Lewenstam A. Fully automated potentiometric determination of ionized magnesium in blood serum ionized magnesium. Anal Chim Acta 1990;236:331-5.
31. Hristova EN, Cecco S, Niemela JE, Rehak NN, Elin RJ. Analyzer-dependent differences in results for ionized calcium, ionized magnesium, sodium and pH. Clin Chem 1995;41:1649-53.
32. Csako G, Rehak NN, Elin RJ. Falsely high ionized magnesium results by ion-selective electrode method in severe hypomagnesemia. Eur J Clin Chem Clin Biochem 1997;35:701-9.
33. Rehak NN, Cecco SA, Niemela JE, Elin RJ. Thiocyanate in smokers interferes with the Nova magnesium ion-selective electrode. Clin Chem 1997;43:1595-600.
34. Malinowska E, Manzoni A, Meyerhoff ME. Potentiometric response of magnesium-selective membrane electrode in the presence of nonionic surfactants. Anal Chim Acta 1999;382:265-75.
35. Laha T, Bremner D, Henderson P, Malik S, Kenny MA. Specific heparin preparations interfere with the measurement of ionized magnesium. Clin Chem 1994;40:1092-3.
36. Lyon ME, Guarjardo M, Laha T, Malik S, Henderson PJ, Kenny MA. Zinc heparin introduces a preanalytical error in the measurement of ionized calcium concentration. Scand J Clin Lab Invest 1995;55:61-5.
37. Wilhite TR, Smith CH, Landt M. Interference of zinc heparin anticoagulant in determination of plasma magnesium [letter]. Clin Chem 1994;40:848-9.
38. Külpmann WR, Dreier M. Drug interference in the measurement of ionized magnesium in serum. In: D'Orazio P, Fogh-Andersen N, Larsson L, editors. The confluence of critical care analysis and near patient testing. Madison, WI: Omnipress, 1998:380.
39. Lewenstam A, Blomqvist N, Öst J. Determination and significance of ionized magnesium. Kliin Lab 1993;10:60-3.
40. Fogh-Andersen N, Siggaard-Andersen O. Acid-base induced changes in the distribution of water between plasma and erythrocytes, as measured with a sodiumion-selective electrode. Clin Chem 1984;30:1843-5.
41. Fogh-Andersen N, Altura BM, Altura B, Siggaard-Andersen O. Composition of interstitial fluid. Clin Chem 1995;41:1522-5.
42. Fogh-Andersen N, Altura BM, Altura B, Siggaard-Andersen O. Changes in plasma ionized calcium and magnesium in blood donors after donation of 450 ml blood. Effects of hemodilution and Donnan equilibrium. Scand J Clin Lab Invest 1996;56(Suppl 224):245-50.
43. 2+ ISEs, with some notes on sample handling. Scand J Clin Lab Invest 1994;54(Suppl 217):89-96.