Studies on oligosaccharyl transferase in yeast

Acta Biochimica Polonica

Volumn 54, Issue 4, 2007, Pages 673-677

  Lennarz, William J ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Oligosaccharyl transferase; Protein glycosylation; Yeast

Indexed keywords

ARCHAEA; EUKARYOTA;

EID: 38149139290     PISSN: 0001527X     EISSN: 1734154X     Source Type: Journal    
DOI: 10.18388/abp.2007_3131     Document Type: Review

References (36)

1. Bause E, Wesemann M, Bartoschek A, Breuer W (1997) Epoxyethylglycyl peptides as inhibitors of oligosaccharyltransferase: Double-labelling of the active site. Biochem J 322: 95-102.
2. Beatson S, Ponting CP (2004) GIFT domains: Linking eukaryotic intraflagellar transport and glycosylation to bacterial gliding. Trends Biochem Sci 29: 396-399.
3. Breuer W, Bause E (1995) Oligosaccharyl transferase is a constitutive component of an oligomeric protein complex from pig liver endoplasmic reticulum. Eur J Biochem 228: 689-696.
4. Chavan M, Yan A, Lennarz WJ (2005) Subunits of the translocon interact with components of the oligosaccharyl transferase complex. J Biol Chem 280: 22917-22924.
5. Chavan M, Chen Z, Li G, Schindelin H, Lennarz WJ, Li H (2006) Dimeric organization of the yeast oligosaccharyl transferase complex. Proc Natl Acad Sci USA 103: 8947-8952.
6. Chi JH, Roos J, Dean N (1996) The OST4 gene of Saccharomyces cerevisiae encodes an unusually small protein required for normal levels of oligosaccharyltransferase activity. J Biol Chem 271: 3132-3140.
7. Dempski Jr RE, Imperiali B (2004) Heterologous expression and biophysical characterization of soluble oligosaccharyl transferase subunits. Arch Biochem Biophys 431: 63-70.
8. Gonen T, Sliz P, Kistler J, Cheng Y, Walz T (2004) Aquaporin-1 membrane junctions reveal the structure of a closed water pore. Nature 429: 193-197.
9. Henderson R, Baldwin JM, Ceska TA, Zemlin F, Beckmann E, Downing KH (1990) An atomic model for the structure of bacteriorhodopsin. Biochem Soc Trans 18: 844.
10. Karaoglu D, Kelleher DJ, Gilmore R (2001) Allosteric regulation provides a molecular mechanism for preferential utilization of the fully assembled dolichol-linked oligosaccharide by the yeast oligosaccharyltransferase. Biochemistry 40: 12193-12206.
11. Kelleher DJ, Gilmore R (1997) DAD1, the defender against apoptotic cell death, is a subunit of the mammalian oligosaccharyltransferase. Proc Natl Acad Sci USA 94: 4994-4999.
12. Kelleher DJ, Kreibich G, Gilmore R (1992) Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein. Cell 69: 55-65.
13. Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R (2003) Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. Mol Cell 12: 101-111.
14. Kim H, Park H, Montalvo L, Lennarz WJ (2000) Studies on the role of the hydrophobic domain of Ost4p in interactions with other subunits of yeast oligosaccharyl transferase. Proc Natl Acad Sci USA 97: 1516-1520.
15. Kim H, Yan Q, Von Heijne G, Caputo GA, Lennarz WJ (2003) Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 100: 7460-7464.
16. Knauer R, Lehle L (1999) The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex. J Biol Chem 274: 17249-17256.
17. Kuhlbrandt W, Wang DN, Fujiyoshi Y (1994) Atomic model of plant light-harvesting complex by electron crystallography. Nature 367: 614-621.
18. Kumar V, Heinemann FS, Ozols J (1994) Purification and characterization of avian oligosaccharyltransferase. Complete amino acid sequence of the 50-kDa subunit. J Biol Chem 269: 13451-13457.
19. Kumar V, Korza G, Heinemann FS, Ozols J (1995) Human oligosaccharyltransferase: isolation, characterization, and the complete amino acid sequence of 50-kDa subunit. Arch Biochem Biophys 320: 217-223.
20. Li G, Yan Q, Oen HO, Lennarz WJ (2003) A specific segment of the transmembrane domain of Wbp1p is essential for its incorporation into the oligosaccharyl transferase complex. Biochemistry 42: 11032-11039.
21. Mayumi I, Nobuo M, Obita T, Kamishikiryo J, Maenaka K, Kohda D (2007) Purification, crystallization and the preliminary X-ray diffraction studies of the soluble domain of the oligosaccharyltransferase STT3 subunit from the thermophilic archaeon Pyrococcus furiosus. Acta Cryst. F63: 798-801.
22. Murata K, Mitsuoka K, Hirai T, Walz T, Agre P, Heymann JB, Engel A, Fujiyoshi Y (2000) Structural determinants of water permeation through aquaporin-1. Nature 407: 599-605.
23. Nilsson I, Kelleher DJ, Miao Y, Shao Y, Kreibich G, Gilmore R, von Heijne G, Johnson AE (2003) Photocross-linking of nascent chains to the STT3 subunit of the oligosaccharyltransferase complex. J Cell Biol 161: 715-725.
24. Pathak R, Hendrickson TL, Imperiali B (1995) Sulfhydryl modification of the yeast Wbp1p inhibits oligosaccharyl transferase activity. Biochemistry 34: 4179-4185.
25. Reiss G, te Heesen S, Gilmore R, Zufferey R, Aebi M (1997) A specific screen for oligosaccharyltransferase mutations identifies the 9 kDa OST5 protein required for optimal activity in vivo and in vitro. EMBo J 16: 1164-1172.
26. Spirig U, Bodmer D, Wacker M, Burda P, Aebi M (2005) The 3.4-kDa Ost4 protein is required for the assembly of two distinct oligosaccharyltransferase complexes in yeast. Glycobiology 15: 1396-1406.
27. te Heesen S, Knauer R, Lehle L, Aebi M (1993) Yeast Wbp1p and Swp1p form a protein complex essential for oligosaccharyl transferase activity. EMBo J 12: 279-284.
28. Wacker M, Linton D, Hitchen PG, Nita-Lazar M, Haslam SM, North SJ, Panico M, Morris HR, Dell A, Wren BW, Aebi M (2002) N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science 298: 1790-1793.
29. Wilson CM, Kraft C, Duggan C, Ismail N, Crawshaw SG, High S (2005) Ribophorin I associates with a subset of membrane proteins after their integration at the Sec61 translocon. J Biol Chem 280: 4195-4206.
30. Yan Q, Lennarz WJ (2002a) Studies on the function of oligosaccharyl transferase subunits: A glycosylatable pho toprobe binds to the luminal domain of Ost1p. Proc Natl Acad Sci USA 99: 15994-15999.
31. Yan Q, Lennarz WJ (2002b) Studies on the function of oligosaccharyl transferase subunits. Stt3p is directly involved in the glycosylation process. J Biol Chem 277: 47692-47700.
32. Yan A, Lennarz WJ (2005) Two oligosaccharyl transferase complexes exist in yeast and associate with two different translocons. Glycobiology 15: 1407-1415.
33. Yan Q, Prestwich GD, Lennarz WJ (1999) The Ost1p subunit of yeast oligosaccharyl transferase recognizes the peptide glycosylation site sequence, -Asn-X-Ser/Thr-. J Biol Chem 274: 5021-5025.
34. Yan A, Ahmed E, Yan Q, Lennarz WJ (2003) New findings on interactions among the yeast oligosaccharyl transferase subunits using a chemical cross-linker. J Biol Chem 278: 33078-33087.
35. Yan A, Wu E, Lennarz WJ (2005) Studies of yeast oligosaccharyl transferase subunits using the split-ubiquitin system: Topological features and in vivo interactions. Proc Natl Acad Sci USA 102: 7121-7126.
36. Zubkov S, Lennarz WJ, Mohanty S (2004) Structural basis for the function of a minimembrane protein subunit of yeast oligosaccharyltransferase. Proc Natl Acad Sci USA 101: 3821-3826.