Allergen specific immunotherapy is safe and effective in patients with systemic mastocytosis and Hymenoptera allergy

Journal of Allergy and Clinical Immunology

Volumn 121, Issue 1, 2008, Pages 256-257

  Bonadonna, Patrizia ^a   Zanotti, Roberta ^b   Caruso, Beatrice ^a   Castellani, Luca ^c   Perbellini, Omar ^b   Colarossi, Sabrina ^d   Chilosi, Marco ^b   Dama, Annarita ^a   Schiappoli, Michele ^a   Pizzolo, Giovanni ^b   Senna, Gianenrico ^a   Passalacqua, Giovanni ^e  

^a Verona General Hospital   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

^c Ospedale Santa Maria del Carmine   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; CETIRIZINE; TRYPTASE;

ADULT; AGED; ALLERGEN SPECIFIC IMMUNOTHERAPY; ANAPHYLAXIS; ASPIRATION BIOPSY; BLOOD LEVEL; BONE MARROW BIOPSY; CELL ACTIVATION; CELL INFILTRATION; CLINICAL ARTICLE; DRUG DOSE ESCALATION; FEMALE; HIGH RISK PATIENT; HUMAN; HYMENOPTERA; IMMUNOTHERAPY; INSECT ALLERGY; LETTER; MALE; MAST CELL; MEASUREMENT; PRIORITY JOURNAL; RISK BENEFIT ANALYSIS; SKIN BIOPSY; SKIN TEST; SYSTEMIC MASTOCYTOSIS; URTICARIA PIGMENTOSA; VACCINATION;

ADULT; AGED; ANIMALS; BEE VENOMS; DESENSITIZATION, IMMUNOLOGIC; FEMALE; HUMANS; HYMENOPTERA; HYPERSENSITIVITY, IMMEDIATE; INSECT BITES AND STINGS; MALE; MASTOCYTOSIS; MIDDLE AGED; TREATMENT OUTCOME; TRYPTASES;

EID: 38149133616     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.10.014     Document Type: Letter

References (9)

1. Valent P., Akin C., Sperr W.R., Arock M., Lechner K., Bennett J.M., et al. Diagnosis and treatment of systemic mastocytosis. Br J Haematol 122 (2003) 695-717
2. Haeberli G., Bronnimann M., Hunziker T., and Muller U. Elevated basal serum tryptase and hymenoptera venom allergy: relation to severity of sting reactions and to safety and efficacy of venom immunotherapy. Clin Exp Allergy 33 (2003) 1216-1220
3. Kors J.W., van Doormaal J.J., and de Monchy J.G. Anaphylactoid shock following Hymenoptera sting as a presenting symptom of systemic mastocytosis. J Intern Med 233 (1993) 255-258
4. Oude Elberink J.N., de Monchy J.G., Kors J.W., van Doormaal J.J., and Dubois A.E. Fatal anaphylaxis after a yellow jacket sting, despite venom immunotherapy, in two patients with mastocytosis. J Allergy Clin Immunol 99 (1997) 153-154
5. Dubois A.E. Mastocytosis and Hymenoptera allergy. Curr Opin Allergy Clin Immunol 4 (2004) 291-295
6. Fricker M., Helbling A., Schwartz L., and Müller U. Hymenoptera sting anaphylaxis and urticaria pigmentosa: clinical findings and results of venom immunotherapy in ten patients. J Allergy Clin Immunol 100 (1997) 11-15
7. Bilò M.B., Rueff F., Mosbech H., Bonifazi F., Oude-Elberinck A., et al. Diagnosis of Hymenoptera venom allergy. Allergy 60 (2005) 1339-1349
8. Rueff F, Wenderoth A, Przybilla B. Patients still reacting to a sting challenge while receiving conventional Hymenoptera venom immunotherapy are protected by increased venom doses.
9. Akin C., Scott L.M., Kocabas C.N., Kushnir-Sukhov N., Brittain E., Noel P., et al. Demonstration of an aberrant mast cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis. Blood 110 (2007) 2331-2333