Glucosamine and its N-acetyl-phenylalanine derivative prevent TNF-α-induced transcriptional activation in human chondrocytes

Clinical and Experimental Rheumatology

Volumn 25, Issue 6, 2007, Pages 847-852

  D'Abusco, Anna Scotto ^a   Cicione, Claudia ^a   Calamia, Valentina ^a   Negri, Rodolfo ^a   Giordano, Cesare ^a   Grigolo, Brunella ^b   Politi, Laura ^a   Scandurra, Roberto ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Chondrocyte gene expression; Chondrocytes; Glucosamine; Osteoarthritis; TNF stimulation

Indexed keywords

CARRIER PROTEIN; CELL CYCLE PROTEIN; GLUCOSAMINE; GLUCOSAMINE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; N ACETYLPHENYLALANINE; PROTEIN C JUN; PROTEIN CUL 2; PROTEIN G1S; PROTEIN RND1; SOMATOMEDIN BINDING PROTEIN 6; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE CELL; CELL CULTURE; CELL GROWTH; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; GENE INACTIVATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION;

CELL LINE; CHONDROCYTES; CULLIN PROTEINS; DOWN-REGULATION; GENE EXPRESSION; GLUCOSAMINE; HUMANS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOARTHRITIS; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO GTP-BINDING PROTEINS; RNA, MESSENGER; TNF RECEPTOR-ASSOCIATED FACTOR 6; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 38149128156     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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