CMV quantitative PCR in the diagnosis of CMV disease in patients with HIV-infection - A retrospective autopsy based study

BMC Infectious Diseases

Volumn 7, Issue , 2007, Pages

  Brantsaeter, Arne B ^a,b   Holberg Petersen, Mona ^a   Jeansson, Stig ^a   Goplen, Anne K ^a   Bruun, Johan N ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b VESTRE VIKEN HOSPITAL TRUST   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; VIRUS DNA;

ADULT; ARTICLE; AUTOPSY; CYTOMEGALOVIRUS INFECTION; DIAGNOSTIC VALUE; EYE BIOPSY; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OPHTHALMOSCOPY; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RETINITIS; RETROSPECTIVE STUDY; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; SUPERINFECTION; VIREMIA; VIRUS DETECTION; VIRUS LOAD; AIDS RELATED COMPLEX; BLOOD; CYTOMEGALOVIRUS; EVALUATION; GENETICS; ISOLATION AND PURIFICATION; METHODOLOGY; NORWAY; PREDICTION AND FORECASTING; UNIVERSITY HOSPITAL; VIROLOGY;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; AUTOPSY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; FEMALE; HIV INFECTIONS; HOSPITALS, UNIVERSITY; HUMANS; MALE; NORWAY; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; VIRAL LOAD; VIREMIA;

EID: 38149109063     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-7-127     Document Type: Article

References (32)

1. Mocroft A Sabin CA Youle M Madge S Tyrer M Devereux H Deayton J Dykhoff A Lipman MC Phillips AN Johnson MA Changes in AIDS-defining illnesses in a London Clinic, 1987-1998 J Acquir Immune Defic Syndr 1999, 21:401-407 10.1097/01.pas.0000213299.11649.106 10458621
2. Salmon-Ceron D Mazeron MC Chaput S Boukli N Senechal B Houhou N Katlama C Matheron S Fillet AM Gozlan J Leport C Jeantils V Freymuth F Costagliola D Plasma cytomegalovirus DNA, pp65 antigenaemia and a low CD4 cell count remain risk factors for cytomegalovirus disease in patients receiving highly active antiretroviral therapy AIDS 2000, 14:1041-1049 10.1097/00002030-200005260-00017 10853987
3. Deayton JR Sabin CA Johnson MA Emery VC Wilson P Griffiths PD Importance of cytomegalovirus viraemia in risk of disease progression and death in HIV-infected patients receiving highly active antiretroviral therapy Lancet 2004, 363:2116-2121 10.1016/S0140-6736(04)16500-8 15220032
4. Dore GJ Marriott DJ Duflou JA Clinico-pathological study of cytomegalovirus (CMV) in AIDS autopsies: Under-recognition of CMV pneumonitis and CMV adrenalitis Aust N Z J Med 1995, 25:503-506 8588772
5. Hofman P Saint-Paul MC Battaglione V Michiels JF Loubiere R Autopsy findings in the acquired immunodeficiency syndrome (AIDS). A report of 395 cases from the south of France Pathol Res Pract 1999, 195:209-217 10337658
6. Lyon R Haque AK Asmuth DM Woods GL Changing patterns of infections in patients with AIDS: A study of 279 autopsies of prison inmates and nonincarcerated patients at a university hospital in eastern Texas, 1984-1993 [see comments] Clin Infect Dis 1996, 23:241-247 8842257
7. Pillay D Lipman MC Lee CA Johnson MA Griffiths PD McLaughlin JE A clinico-pathological audit of opportunistic viral infections in HIV- infected patients AIDS 1993, 7:969-974 10.1097/00002030-199307000-00010 8395189
8. Wilkes MS Fortin AH Felix JC Godwin TA Thompson WG Value of necropsy in acquired immunodeficiency syndrome Lancet 1988, 2:85-88 10.1016/ S0140-6736(88)90014-1 2898707
9. Brantsaeter AB Liestol K Goplen AK Dunlop O Bruun JN CMV disease in AIDS patients: Incidence of CMV disease and relation to survival in a population-based study from Oslo Scandinavian Journal of Infectious Diseases 2002, 34:50-55 10.1080/00365540110076976 11874165
10. d'Arminio MA Mainini F Testa L Vago L Balotta L Nebuloni M Antinori S Bini T Moroni M Predictors of cytomegalovirus disease, natural history and autopsy findings in a cohort of patients with AIDS AIDS 1997, 11:517-524 9084800
11. Yeni P Prise en charge médicale des personnes infectées par le VIH.Rapport 2006. Recommandations du groupe d'experts. Paris, Flammarion 2006 250 250
12. Masur H Kaplan JE Holmes KK Guidelines for Preventing Opportunistic Infections among HIV-Infected Persons--2002: Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America Ann Intern Med 2002, 137:435-478 12617574
13. Blank BS Meenhorst PL Mulder JW Weverling GJ Putter H Pauw W van Dijk WC Smits P Lie AL Reiss P Lange JM Value of different assays for detection of human cytomegalovirus (HCMV) in predicting the development of HCMV disease in human immunodeficiency virus-infected patients J Clin Microbiol 2000, 38:563-569 86149 10655346
14. Bowen EF Sabin CA Wilson P Griffiths PD Davey CC Johnson MA Emery VC Cytomegalovirus (CMV) viraemia detected by polymerase chain reaction identifies a group of HIV-positive patients at high risk of CMV disease AIDS 1997, 11:889-893 10.1097/00002030-199707000-00008 9189214
15. Bowen EF Cytomegalovirus reactivation in patients infected with HIV: The use of polymerase chain reaction in prediction and management Drugs 1999, 57:735-741 10.2165/00003495-199957050-00006 10353298
16. Dodt KK Jacobsen PH Hofmann B Meyer C Kolmos HJ Skinhoj P Norrild B Mathiesen L Development of cytomegalovirus (CMV) disease may be predicted in HIV- infected patients by CMV polymerase chain reaction and the antigenemia test AIDS 1997,11: F21-F28 10.1097/ 00002030-199703110-00001 9147416
17. Spector SA Wong R Hsia K Pilcher M Stempien MJ Plasma cytomegalovirus (CMV) DNA load predicts CMV disease and survival in AIDS patients J Clin Invest 1998, 101:497-502 508590 9435323
18. Wattanamano P Clayton JL Kopicko JJ Kissinger P Elliot S Jarrott C Rangan S Beilke MA Comparison of three assays for cytomegalovirus detection in AIDS patients at risk for retinitis J Clin Microbiol 2000, 38:727-732 86188 10655375
19. Yoshida A Hitomi S Fukui T Endo H Morisawa Y Kazuyama Y Osumi K Oka S Kimura S Diagnosis and monitoring of human cytomegalovirus diseases in patients with human immunodeficiency virus infection by use of a real-time PCR assay Clin Infect Dis 2001, 33:1756-1761 10.1086/323782 11641826
20. Boivin G Handfield J Toma E Murray G Lalonde R Bergeron MG Comparative evaluation of the cytomegalovirus DNA load in polymorphonuclear leukocytes and plasma of human immunodeficiency virus- infected subjects [see comments] J Infect Dis 1998, 177:355-360 9466521
21. Casado JL Arrizabalaga J Montes M Marti-Belda P Tural C Pinilla J Gutierrez C Portu J Schuurman R Aguirrebengoa K Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. Spanish CMV- AIDS Study Group AIDS 1999, 13:1497-1502 10.1097/00002030-199908200-00009 10465073
22. Nokta MA Holland F De G V Emery VC Jacobson MA Griffiths P Pollard RB Feinberg JE Cytomegalovirus (CMV) polymerase chain reaction profiles in individuals with advanced human immunodeficiency virus infection: relationship to CMV disease J Infect Dis 2002, 185:1717-1722 10.1086/ 340651 12085316
23. Shinkai M Bozzette SA Powderly W Frame P Spector SA Utility of urine and leukocyte cultures and plasma DNA polymerase chain reaction for identification of AIDS patients at risk for developing human cytomegalovirus disease J Infect Dis 1997, 175:302-308 9203650
24. Spector SA Hsia K Crager M Pilcher M Cabral S Stempien MJ Cytomegalovirus (CMV) DNA load is an independent predictor of CMV disease and survival in advanced AIDS J Virol 1999, 73:7027-7030 112790 10400803
25. Erice A Tierney C Hirsch M Caliendo AM Weinberg A Kendall MA Polsky B Cytomegalovirus (CMV) and human immunodeficiency virus (HIV) burden, CMV end-organ disease, and survival in subjects with advanced HIV infection (AIDS clinical trials group protocol 360) Clinical Infectious Diseases 2003, 37:567-578 10.1086/375843 12905142
26. Wiselka MJ Nicholson KG Rowley S Bibby K Cytomegalovirus viraemia has poor predictive value for the development of cytomegalovirus disease in patients with advanced HIV-infection J Infect 1999, 39:187-192 10.1016/ S0163-4453(99)90047-6 10714793
27. Pellegrin I Garrigue I Binquet C Chene G Neau D Bonot P Bonnet F Fleury W Pellegrin JL Evaluation of new quantitative assays for diagnosis and monitoring of cytomegalovirus disease in human immunodeficiency virus-positive patients Journal of Clinical Microbiology 1999, 37:3124-3132 85509 10488165
28. Bestetti A Pierotti C Terreni M Zappa A Vago L Lazzarin A Cinque P Comparison of three nucleic acid amplification assays of cerebrospinal fluid for diagnosis of cytomegalovirus encephalitis J Clin Microbiol 2001, 39:1148-1151 87891 11230445 10.1128/JCM.39.3.1148-1151.2001
29. Wohl DA Zeng D Stewart P Glomb N Alcorn T Jones S Handy J Fiscus S Weinberg A Gowda D van der HC Cytomegalovirus viremia, mortality, and end-organ disease among patients with AIDS receiving potent antiretroviral therapies J Acquir Immune Defic Syndr 2005, 38:538-544 10.1097/01.qai.0000155204.96973.c3 15793363
30. Strippoli GF Hodson EM Jones C Craig JC Preemptive treatment for cytomegalovirus viremia to prevent cytomegalovirus disease in solid organ transplant recipients Transplantation 2006, 81:139-145 10.1097/ 01.tp.0000183970.71366.da 16436954
31. Qamruddin AO Oppenheim BA Guiver M Mutton KJ Chopra R Screening for cytomegalovirus (CMV) infection in allogeneic bone marrow transplantation using a quantitative whole blood polymerase chain reaction (PCR) method: Analysis of potential risk factors for CMV infection Bone Marrow Transplant 2001, 27:301-306 10.1038/sj.bmt.1702778 11277178
32. Gallant JE Moore RD Richman DD Keruly J Chaisson RE Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. The Zidovudine Epidemiology Study Group [see comments] J Infect Dis 1992, 166:1223-1227 1358986