Cytomegalovirus (CMV) and human immunodeficiency virus (HIV) burden, CMV end-organ disease, and survival in subjects with advanced HIV infection (AIDS Clinical Trials Group Protocol 360)

Clinical Infectious Diseases

Volumn 37, Issue 4, 2003, Pages 567-578

  Erice, Alejo ^a,g   Tierney, C ^b   Hirsch, M ^c   Caliendo, A M ^d   Weinberg, A ^e   Kendall, M A ^b   Polsky, B ^f  

^a UNIVERSITY OF MINNESOTA   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f Columbia Univ Coll of Phys/Surgs ^*  (United States)

^g Hospital Asepeyo   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA; VIRUS RNA;

ADULT; ARTICLE; CLINICAL TRIAL; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; MULTIPLE ORGAN FAILURE; NONHUMAN; PRIORITY JOURNAL; SUPERINFECTION; SURVIVAL; VIRUS DETECTION;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIVIRAL AGENTS; CD4 LYMPHOCYTE COUNT; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DNA, VIRAL; FEMALE; FOLLOW-UP STUDIES; HIV; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RNA, VIRAL; SURVIVAL RATE; VIRAL LOAD;

EID: 0041941609     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/375843     Document Type: Article

References (26)

1. Drew WL. Cytomegalovirus infection in patients with AIDS. Clin Infect Dis 1992; 14:608-15.
2. Pertel P, Hirschtick R, Phair J, Chmiel J, Poggensee L, Murphy R. Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus. J Acquir Immun Defic Syndr 1992; 5:1069-74.
3. Gallant JE, Moore RD, Richman DD, Keruly J, Chaisson RE. Incidence and natural history of cytomegalovirus disease in patients with advanced human immunodeficiency virus disease treated with zidovudine. J Infect Dis 1992; 166:1223-7.
4. Jacobson MA. Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. N Engl J Med 1997; 337:105-14.
5. Hansen KK, Ricksten A, Hofmann B, Norrild B, Olofsson S, Mathiesen L. Detection of cytomegalovirus DNA in serum correlates with clinical cytomegalovirus retinitis in AIDS. J Infect Dis 1994; 170:1271-4.
6. Spector SA, Wong R, Hsia K, Pilcher M, Stempien MJ. Plasma cytomegalovirus (CMV) DNA predicts CMV disease and survival in AIDS patients. J Clin Invest 1998; 101:497-502.
7. Spector SA, Hsia K, Crager M, Pilcher M, Caabral S, Stempien MJ. Cytomegalovirus (CMV) DNA load is an independent predictor of CMV disease and survival in advanced AIDS. J Virol 1999; 73:7027-30.
8. Rasmussen L, Zipeto D, Wolitz RA, DoMing A, Efron B, Merigan TC. Risk for retinitis in patients with AIDS can be assessed by quantitation of threshold levels of cytomegalovirus DNA burden in blood. J Infect Dis 1997; 176:1146-55.
9. Griffiths PD, Feinberg JE, Fry J, et al. The effect of valacyclovir on cytomegalovirus viremia and viruria detected by polymerase chain reaction in patients with advanced human immunodeficiency virus disease. J Infect Dis 1998; 177:57-64.
10. Williams PL, Currier JS, Swindells S. Joint effects of HIV-1 RNA levels and CD4 lymphocyte cells on the risk of specific opportunistic infections. AIDS 1999; 13:1035-44.
11. Palella FJ, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med 1998; 338:853-60.
12. Skolnik PR, Kosloff BR, Hirsch MS. Bidirectional interactions between human immunodeficiency virus type 1 and cytomegalovirus. J Infect Dis 1988; 157:508-14.
13. Mazzulli T, Drew LW, Yen-Lieberman B, et al. Multicenter comparison of the Digene hybrid capture CMV DNA assay (version 2.0), the pp65 antigenemia assay, and cell culture for detection of cytomegalovirus viremia. J Clin Microbiol 1999; 37:958-63.
14. Caliendo AM, Schuurman R, Yen-Lieberman B, et al. Comparison of quantitative and qualitative PCR assays for cytomegalovirus DNA in plasma. J Clin Microbiol 2001; 39:1334-8.
15. Erice A, Brambilla D, Bremer J, et al. Performance characteristics of the bDNA 3.0 assay for detection and quantitation of HIV-1 RNA in plasma. J Clin Microbiol 2000; 38:2837-45.
16. Gray RJ. A class of k-sample tests for comparing the cumulative incidence of a competing risk. Ann Statistics 1988; 16:1140-54.
17. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. JAMA 1958; 53:457-81.
18. Cox DR. Regression models and life tables. J Royal Statistical Soc 1972; 34:187-220.
19. Spector SA, McKinley GF, Lalezari JP, et al. Oral ganciclovir for the prevention of cytomegalovirus disease in persons with AIDS. N Engl J Med 1996; 334:1491-7.
20. Casado JL, Arrizabalaga J, Montes M, et al. Incidence and risk factors for developing cytomegalovirus retinitis in HIV-infected patients receiving protease inhibitor therapy. AIDS 1999; 13:1497-502.
21. Salmon-Céron D, Mazeron MC, Chaput S, et al. Plasma cytomegalovirus DNA, pp65 antigenemia and a low CD4 cell count remain risk factors for cytomegalovirus disease in patients receiving highly active antiretroviral therapy. AIDS 2000; 14:1041-9.
22. Autran B, Carcelain G, Li TS, et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 1997; 277:112-6.
23. Li TS, Tubiana R, Katlama C, Calvez V, Ait Mohand H, Autran B. Long lasting recovery in CD4 T-cell function and viral load reduction after highly active antiretroviral therapy in advanced HIV-1 disease. Lancet 1998; 351:1682-6.
24. Lyles RH, Chu C, Mellors JW, et al. Prognostic value of plasma HIV RNA in the natural history of Pneumocystis carinii pneumonia, Cytomegalovirus, and Mycobacterium avium complex. AIDS 1999; 13:341-9.
25. Notka MA, Holland F, De Gruttola V, et al. Cytomegalovirus (CMV) polymerase chain reaction profiles in individuals with advanced human immunodeficiency virus infection: relationship to CMV disease. I Infect Dis 2002; 185:1717-22.
26. Wattanamano P, Clayton IL, Kopicko JI, et al. Comparison of three assays for cytomegalovlrus detection in AIDS patients at risk for retinitis. J Clin Microbiol 2000; 38:727-32.