The role of the endometrium in endocrine regulation of the animal oestrous cycle

Reproduction in Domestic Animals

Volumn 43, Issue 1, 2008, Pages 80-91

  Krzymowski, T ^a   Stefanczyk Krzymowska S ^a  

^a INSTITUTE OF ANIMAL REPRODUCTION AND FOOD RESEARCH   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN F2 ALPHA;

ANIMAL; ENDOMETRIUM; ESTRUS CYCLE; FEMALE; LUTEOLYSIS; PHYSIOLOGY; REVIEW; UTERUS; VASCULARIZATION;

ANIMALS; DINOPROST; ENDOMETRIUM; ESTROUS CYCLE; FEMALE; LUTEOLYSIS; UTERUS;

ANIMALIA; OVIS ARIES; SUIDAE;

EID: 38149087717     PISSN: 09366768     EISSN: 14390531     Source Type: Journal    
DOI: 10.1111/j.1439-0531.2007.00859.x     Document Type: Review

References (106)

1. Ancelin M, Chollet-Martin S, Herwe MA, Legrand C, El Benna J, Perrot-Applanat M, 2004 : Vascular endothelial growth factor VEGF 189 induces human neutrophil chemotaxis in extravascular tissue via autocrine amplification mechanism. Lab Invest 84, 502 512.
2. Ashworth MD, Ross JW, Hu J, White FJ, Stein DR, DeSilva U, Johnson GA, Spencer TE, Geisert RD, 2006 : Expression of porcine endometrial prostaglandin synthase during the estrous cycle and early pregnancy, and following endocrine disruption of pregnancy. Biol Reprod 74, 1007 1015.
3. 2 and response to oxytocin in cultured epithelial and stromal cells of the bovine endometrium. Biol Reprod 54, 371 379.
4. Atkinson DA, 1968 : The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. Biochemistry 7, 4030 4034.
5. Attalah AA, Lee JB, 1980 : Indomethacin, salycylates and prostaglandin binding. Prostaglandins 19, 311 318.
6. Bae SE, Watson ED, 2003 : A light microscopic and ultrastructural study on the presence and location of oxytocin in the equine endometrium. Theriogenology 60, 909 921.
7. Bankowski K, Manning M, Seto J, Halder J, Sawyer W, 1980 : Design and synthesis of potent in vivo antagonist of oxytocin. Internatl J Peptide Protein Res 16, 382 391.
8. Banu SK, Arosh JA, Chapdelaine P, Fortier MA, 2003 : Molecular cloning and spatio-temporal expression of the prostaglandin transporter: a basis for the action of prostaglandins in the bovine reproductive system. Proc Nat Acad Sci 100, 11747 11752.
9. Bao Y, Pucci ML, Chan BS, Lu R, 2002 : Prostaglandin transporter PGT is expressed in cell types that synthetize and release prostaglandins. Am J Physiol Renal Physiol 282, F1103 F1110.
10. 2α by the uterine endometrium. Prostaglandins 14, 397 401.
11. Bito LZ, 1972 : Accumulation and apparent active transport of prostaglandins by some rabbit tissues in vitro. J Physiol 221, 371 387.
12. Bito LZ, 1975 : Saturable, energy-dependent, transmembrane transport of prostaglandins against concentration gradients. Nature 256, 134 136.
13. 2 secretion by cultured porcine endometrial cells. Reproduction 130, 105 112.
14. Blitek A, Wacławik A, Kaczmarek MM, Stadejek T, Pejsak Z, Ziȩcik AJ, 2006 : Expression of cyclooxygenase-1 and -2 in the porcine endometrium during the oestrous cycle and early pregnancy. Rep Dom Anim 41, 251 257.
15. Brown GC, 1992 : Control of respiration and ATP synthesis in mammalian mitochondria and cells. Biochem J 284, 1 13.
16. 2α in cyclic and early pregnant swine. Biol Reprod 55, 838 843.
17. 2α from endometrial cells of swine in the presence of progesterone. Domest Anim Endocrinol 23, 435 445.
18. 2 transport across the plasma membrane of HeLa cells and Xenopus oocytes expressing the prostaglandin transporter ''PGT''. J Biol Chem 273, 6689 6697.
19. Charpigny G, Reinaut P, Tamby JP, Creminon Ch, Martal J, Maclouf J, Guillomont M, 1997 : Expression of cyclooxygenase-1 and -2 in ovine endometrium during the estrous cycle and early pregnancy. Endocrinology 138, 2163 2171.
20. Critchley HO, Osei J, Henderson TA, Boswel L, Sales KJ, Jabbour HN, Hirani N, 2006 : Hypoxia-inducible factor-1 (alpha) expression in human endometrium and its regulation by prostaglandin E-series prostanoid receptor 2 (EP2). Endocrinology 147, 742 753.
21. 2α on luteal function in swine. J Anim Sci 39, 392 396.
22. Doboszyńska T, 2002 : The connections of lymphatic vessels draining female reproductive organs with lymphnodes in the pig. Pol J Vet Sci 25, 29 34.
23. Doboszyńska T, Andronowska A, 2004 : Morphological analysis of transportation pathways of microspheres after their introduction into the uterine horn cavity in cycling pigs. Cell Tissue Res 317, 91 99.
24. Doboszyńska T, Maksymowicz M, Andronowska A, Zezula-Szpyra A, Gawrońska B, 1996 : The ultrastructure of lymphatic vessels emanating from the uterus and forming subovarian lymphatic plexus in pigs. Folia Histochem Cytobiol 34, 51 52.
25. 2 from luminal and myometrial surfaces of endometrium from cyclic and pseudopregnant gilts. Prostaglandins 41, 283 301.
26. Fairclough J, Moore LG, McGowan AJ, Peterson AJ, Smith JF, Tervit HR, Watkins WB, 1980 : Temporal relationship between plasma concentrations of 13,14-dihydro-15-keto-prostaglandin F and neurophysin I/II around luteolysis in sheep. Prostaglandins 20, 199 208.
27. Flint APF, Sheldrick EL, 1983 : Evidence for a systemic role for ovarian oxytocin in luteal regression in sheep. J Reprod Fertil 47, 215 225.
28. Flint APF, Leat WMF, Sheldrick EL, Stewart HJ, 1986 : Stimulation of phosphoinoside hydrolysis by oxytocin and the mechanism by which oxytocin controls prostaglandin synthesis in the ovine endometrium. Biochem J 237, 797 805.
29. Ford SP, 1982 : Control of uterine and ovarian blood flow through the estrous cycle and pregnancy in the ewe, sow and cow. J Animal Sci 55 (Suppl. 2 32 42.
30. Ford SP, Christenson RK, 1979 : Blood flow to uteri of sows during the estrous cycle and early pregnancy: local effect of the conceptus on the uterine blood supply. Biol Reprod 21, 617 624.
31. Ford SP, Weber LJ, Stormshak F, 1977 : Role of estradiol-17β and progesterone in regulating constriction of ovine uterine arteries. Biol Reprod 17, 480 483.
32. 2α as the luteolysin in swine. IV. An explanation for the luteotrophic effect of estradiol. Prostaglandins 15, 151 160.
33. 2α as a luteolysin in ovine. IV An explanation for the luteotrophic effect of estradiol. Prostaglandins 15, 151 160.
34. Gawrońska B, Doboszyńska T, Zezula-Szpyra A, 1992 : Lymphatic vessels in the broad ligament of the uterus in swine. Lymphology 25, 90 96.
35. Gawrońska B, Zezula-Szpyra A, Doboszyńska T, Baranowski M, Andronowska A, 1995 : The utero-ovarian arterial anastomoses of the broad ligament of the uterus in sows: a scanning electron and light microscope study. The Tenth European Anatomical Congress, Florence, Acta Anat 152, 106.
36. Gawrońska B, Doboszyńska T, Zezula-Szpyra A, 1997 : Light and scanning electron microscopy of the porcine mesometrial and paraovarian lymphatic networks. Lymphology 30, 26 35.
37. Gilbert CL, Jenkins K, Wathes DC, 1991 : Pulsatile release of oxytocin into the circulation of the ewe during oestrous, mating and the early luteal phase. J Reprod Fertil 91, 337 346.
38. Ginther OJ, Del Campo CH, Rawlings CA, 1973 : Vascular anatomy of the uterus and ovaries and the unilateral luteolytic effect of the uterus: a local venoarterial pathway between uterus and ovaries in sheep. Am J Vet Res 34, 723 728.
39. Gleeson AR, Thorburn GD, Cox RJ, 1974 : Prostaglandin F concentrations in the utero ovarian vein plasma of the sow during the late luteal phase of the estrus cycle. Prostaglandins 5, 521 530.
40. Gross TS, Lacroix MC, Bazer FW, Thatcher WW, Harney JP, 1988 : Prostaglandin secretion by perfused porcine endometrium: further evidence for an endocrine versus exocrine secretion of prostaglandins. Prostaglandins 35, 327 341.
41. Hafez ESE, Ludwig H, 1977 : Scanning electron microscopy of the endometrium. In : Wynn RM (ed. Biology the Uterus. Plenum Press, New York and London, pp. 309 340.
42. 2α is transferred from the uterus to the ovary in the sheep by lymphatic and blood vascular pathway. J Reprod Fertil 74, 645 656.
43. 2α stimulate ovarian oxytocin output in sheep. J Endocrinol 122, 147 159.
44. Hu J, Braileanu GT, Mirando MA, 2001 : Oxytocin stimulates prostaglandin F(2 alpha) secretion from porcine endometrial cells through activation of calcium-dependent protein kinase C. Prostaglandins 65, 85 101.
45. Jankowska K, Doboszyńska T, Postek A, Andronowska A, 2003 : Localization and macrostructure of subuterine lymphatic vessels networks in the bovine uterine broad ligament. Pol J Vet Sci 6, 7 15.
46. Kanai N, Lu R, Satriano JA, Bao Y, Wolkoff AW, Schuster VL, 1995 : Identification and characterization of a prostaglandin transporter. Science 268, 866 869.
47. Kang J, Chapdelaine P, Parent J, Madore E, Laberge PY, Fortier MA, 2005 : Expression of human prostaglandin transporter in the human endometrium across the menstrual cycle. J Clin Endocrinol Metab 90, 2308 2313.
48. 2α metabolites in blood and urine during early pregnancy. Anim Reprod Sci 7, 133 148.
49. 2α penetration from the horn of the uterus to the ovaries in pig. J Reprod Fertil 59, 237 241.
50. Kotwica J, Krzymowski T, Stefańczyk S, Koziorowski M, Czarnocki J, Ruszczyk T, 1983 : A new route of prostaglandin F-2α transfer from the uterus into the ovary in swine. Anim Reprod Sci 5, 303 309.
51. Kotwica G, Franczak A, Okrasa S, Kotwica J, 1999 : Effect of an oxytocin antagonist on prostaglandin F secretion and the course of luteolysis in sows. Acta Vet Hung 47, 249 262.
52. 2α back transfer from the broad ligament vasculature in to the uterus in the gilts and cows. Bull Polish Acad Sci Biol Sci 34, 75 84.
53. Krzymowski T, Stefańczyk-Krzymowska S, 2002 : Uterine blood supply as a main factor involved in the regulation of the estrous cycle - a new theory. Reprod Biol 2, 93 114.
54. Krzymowski T, Stefańczyk-Krzymowska S, 2004 : The estrous cycle and early pregnancy: a new concept of local endocrine regulation. The Vet J 168, 285 296.
55. 2α in the mesometrium: a possible mechanism for prevention of luteal regression. Anim Reprod Sci 11, 259 272.
56. Krzymowski T, Kotwica J, Stefańczyk S, Czarnocki J, Debek J, 1982 : A subovarian exchange mechanism for the countercurrent transfer of ovarian steroid hormones in the pig. J Reprod Fertil 65, 457 465.
57. 2α back transfer from the mesometrium vasculature into the uterus of the gilt during early pregnancy and estrogen-induced pseudopregnancy. Anim Reprod Sci 13, 199 210.
58. Krzymowski T, Kotwica J, Stefańczyk-Krzymowska S, 1990 : Uterine and ovarian counter current pathways in the control of ovarian function in the pig. J Reprod Fertil Suppl 40, 179 191.
59. 2α in the mesometrial vessels as a mechanism for the preventive of luteal regression in early pregnancy. Acta Physiol Pol 40, 23 34.
60. Lacroix MC, Bazer FW, Thatcher WW, Harney JP, 1988 : Prostaglandin secretion by perfused porcine endometrium: further evidence for an endocrine versus exocrine secretion of prostaglandins. Prostaglandins 35, 327 341.
61. Langendijk P, Bouwman EG, Soede NM, Taverne MAM, Kemp B, 2002 : Myometrial activity around estrus in sows: spontaneous activity and effects of estrogens, cloprostenol, seminal plasma and clenbuterol. Therigenology 57, 1563 1577.
62. Lu R, Kanai N, Bao Y, Schuster VI, 1996 : Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA (hPGT). J Clin Invest 98, 1142 1149.
63. Lukaszewska J, Hansel W, 1970 : Extraction and purification of luteolytic activity from bovine endometrial tissue. Endocrinology, 86, 261 270.
64. 2α and corpus luteum regression. Ann N Y Acad Sci 180, 456 472.
65. 2α secretion by the ovine uterus. Adv Prostag Thrombox Res 8, 1329 1344.
66. 2α identified as a luteolytic hormone in sheep. Nat New Biol 238, 129 134.
67. 2α from ovine uterus during luteolysis and its abrogation in early pregnancy. Anim Reprod Sci 7, 31 55.
68. McCracken JA, Custer EE, Lamsa JC, Robinson AG, 1995 : The central oxytocin pulse generator: a pacemaker for luteolysis. Adv Exp Med Biol 395, 133 154.
69. McCracken JA, Custer EE, Eldering JA, Robinson AG, 1996 : The central oxytocin pulse generator: a pacemaker for the ovarian cycle. Acta Neurobiol Exp 56, 819 832.
70. 2α secretion in vitro, and plasma concentrations of ovarian steroids before and during corpus luteum regression in cyclic heifers. Biol Reprod 48, 874 882.
71. Okano A, Okuda K, Takahashi M, Schams D, 1996 : Oxytocin receptors in porcine endometrium during the estrous cycle and early pregnancy. Animal Reprod Sci 41, 61 70.
72. Pall ML, 1985 : GTP: a central regulator of cellular anabolism. Cur Top Cell Reg 25, 1 19.
73. Pampin JB, Rivero SAG, Cepeda XLO, Boquete AV, Vila JF, Fonseca RH, 2006 : Immunohistochemical expression of HIF-1α in response to early myocardial ischemia. J Forensic Sci 51, 120 124.
74. Peterson AJ, Tervit HR, Fairclough RJ, Havik PG, Smith JF, 1976 : Jugular levels of 13,14 dihydro-15-keto-prostaglandin F and progesterone around luteolysis and early pregnancy in the ewe. Prostaglandins 12, 551 558.
75. Rees CP, 1990 : Human menstruation and eicosanoids. Reprod Fertil Dev 2, 467 476.
76. Reynolds LP, Ford SP, 1984 : Contractility of the vascular bed during the oestrous cycle and early pregnancy in gilts. J Reprod Fertil 71, 65 71.
77. Roman Ponce H, Caton D, Thatcher WW, Lehrer R, 1983 : Uterine blood flow in relation to endogenous hormones during estrous cycle and early pregnancy. Am J Physiol 245, R843 R849.
78. 2α in Norvegian semi-domestic reinder (Rangifer tarandus tarandus) during their first reproductive season. J Reprod Fert 105, 307 314.
79. Saffaripour S, Jones MA, 1988 : Prostaglandin (PG) accumulation in vitro by mouse ovaries, oviducts and uteri. Prostaglandins 36, 229 239.
80. Schramm W, McCracken JA, 1982 : Steroid modulation of episodic myometrial activity in conscious sheep. Endocrinology 110, A170.
81. Schuster VL, 1998 : Molecular mechanisms of prostaglandin transport. Ann Rev Physiol 60, 221 242.
82. Schuster VL, 2002 : Prostaglandin transport. Prostaglandins Other Lipid Mediat 68-69, 633 647.
83. Semenza GL, 2000 : HIF-1:mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88, 1474 1480.
84. Stȩpień A, Ziȩcik AJ, 2002 : Second messenger system in the action of LH and oxytocin on porcine endometrial cells in vitro. Theriogenology 57, 2217 2227.
85. Stabenfeldt GH, Kindahl H, Hughes JP, Neeley DP, Liu I, Pascoe D, 1981 : Control of luteolysis in the mare. Acta Vet Scand 77 (Suppl. 159 170.
86. Stefańczyk-Krzymowska S, 1996 : The role of countercurrent transfer of hormone in regulation of the ovary and uterus function in sows. (in Polish). Acta Acad Agric TechOlstenensis, Zootechnika Suppl A, ART Olsztyn 45, 1 59.
87. Stefańczyk-Krzymowska S, Krzymowski T, 2002 : Local adjustment of blood and lymph circulation in the hormonal regulation of reproduction i female pigs- facts, conclusions and suggestions for future research. Reprod Biol 2, 115 132.
88. 2α from the uterine lumen into the venous and arterial blood and into the uterine, mesometrial and ovarian tissue on day 18 of pregnancy in the pig. Anim Reprod Sci 23, 223 235.
89. 2α in the area of mesometrium vasculature in the pig. Bull Pol Academy of Sci Biol Sci 40, 109 115.
90. Stefańczyk-Krzymowska S, Skipor J, Grzegorzewski W, Wa̧sowska B, Krzymowski T, 1994a : Local increase of steroid hormone concentration in blood supplying the uterus and oviduct in anaesthetized and conscious gilts. Anim Reprod Sci 37, 35 41.
91. 2α in the endometrium and myometrium from various sections of the porcine uterine horn during the estrous cycle. Prostaglandins 48, 99 108.
92. Stefańczyk-Krzymowska S, Grzegorzewski W, Wa̧sowska B, Krzymowski T, 1997 : Involvement of adrenoreceptors in the ovarian vascular pedicle in the regulation of counter current transfer of steroid hormones to the arterial blood supplying the oviduct and uterus. Br J Pharmacol 120, 763 768.
93. Stefańczyk-Krzymowska S, Krzymowski T, Wa̧sowska B, Chłopek J, 2002 : Retrograde transfer of ovarian steroid hormones to the ovary in the porcine periovarian vascular complex. Exp Physiol 87, 361 371.
94. 2 into the ovary and its retrograde transfer into the uterus in early pregnant sows. Exp Physiol 90, 807 814.
95. Stefańczyk-Krzymowska S, Wa̧sowska B, Chłopek J, Grzegorzewski W, 2004 : Retrograde transfer of steroid hormones in luteal and follicular phases of porcine oestrous cycles. Exp Physiol 89, 140 144.
96. 2 in early pregnant sow and its physiological consequences. Prostaglandins Other Lipid Mediat 81, 71 79.
97. Trout WE, Smith GW, Gentry PC, Galvin JM, Keisler DH, 1995 : Oxytocin secretion by endometrium of the pig during maternal recognition of pregnancy. Biol Reprod 52 (Suppl.1 189.
98. 2α and apoptosis in the porcine endometrium during the estrous cycle. (in Polish). PhD Dissertation, University of Warmia and Mazury, Olsztyn.
99. Wa̧sowska B, Ludkiewicz B, Stefańczyk-Krzymowska S, Grzegorzewski W, Skipor J, 2001 : Apoptotic cell death in the porcine endometrium during the estrous cycle. Acta Vet Hungar 49, 71 79.
100. Wacławik A, Rivero-Muller A, Blitek A, Kaczmarek MM, Brokken LJS, Watanabe K, Rahman NA, Ziȩcik AJ, 2006 : Molecular cloning and spatiotemporal expression of prostaglandin F synthase and microsomal prostaglandin E synthase-1 in porcine endometrium. Endocrinology 147, 210 221.
101. Wang B, Xiao Ch, Goff K, 2003 : Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium. Biol Reprod 68, 673 679.
102. Weems YS, Lammoglia MA, Lewis AW, Randel RD, Sasser RG, Morita I, Weems CW, 1999 : PGE2 induces its own secretion in vitro by bovine 270-day placenta but not by 200-day placenta. Prostaglandins Other Lipid Mediat 57, 189 205.
103. Whiteaker SS, Mirando MM, Becker WC, Hostetler CE, 1994 : Detection of functional oxytocin receptors on endometrium of pigs. Biol Reprod 51, 92 98.
104. 2α secretion in vitro from endometrium of cyclic pigs on day 15 postestrus. Domest Anim Endocrinol 12, 95 104.
105. 2α as a luteolysin in swine. V. Comparison of prostaglandin F, progestins, estrone and estradiol in uterine flushing from pregnant and nonpregnant gilts. Prostaglandins 20, 837 851.
106. Ziȩcik AJ, 2002 : Old, new and the newest concepts of inhibition of luteolysis during early pregnancy in pig. Domest Anim Endocrinol 23, 265 275.