Sex differences in heritability of ischemic stroke: A systematic review and meta-analysis

Stroke

Volumn 39, Issue 1, 2008, Pages 16-23

  Touzé, Emmanuel ^a,b   Rothwell, Peter M ^a  

^a RADCLIFFE INFIRMARY   (United Kingdom)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cerebrovascular accident; Epidemiology; Family history; Genetics; Risk factors

Indexed keywords

BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; FAMILY HISTORY; HERITABILITY; HUMAN; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SEX DIFFERENCE; STROKE; UNITED KINGDOM; COMPARATIVE STUDY; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; META ANALYSIS; SEXUAL DEVELOPMENT;

FEMALE; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HUMANS; MALE; RISK FACTORS; SEX CHARACTERISTICS; STROKE;

EID: 38149065432     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.107.484618     Document Type: Review

References (55)

1. Flossmann E, Schulz UG, Rothwell PM. Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke. Stroke. 2004;35:212-227.
2. Hassan A, Markus HS. Genetics and ischaemic stroke. Brain. 2000;123:1784-1812.
3. Gretarsdottir S, Thorleifsson G, Reynisdottir ST, Manolescu A, Jonsdottir S, Jonsdottir T, Gudmundsdottir T, Bjarnadottir SM, Einarsson OB, Gudjonsdottir HM, Hawkins M, Gudmundsson G, Gudmundsdottir H, Andrason H, Gudmundsdottir AS, Sigurdardottir M, Chou TT, Nahmias J, Goss S, Sveinbjörnsdottir S, Valdimarsson EM, Jakobsson F, Agnarsson U, Gudnason V, Thorgeirsson G, Fingerle J, Gurney M, Gudbjartsson D, Frigge ML, Kong A, Stefansson K, Gulcher JR. The gene encoding phophodiesterase 4D confers risk of ischemic stroke. Nat Genet. 2003;35:131-138.
4. Helgadottir A, Manolescu A, Thorleifsson G, Gretarsdottir S, Jonsdottir H, Thorsteinsdottir U, Samani NJ, Gudmundsson G, Grant SF, Thorgeirsson G, Sveinbjornsdottir S, Valdimarsson EM, Matthiasson SE, Johannsson H, Gudmundsdottir O, Gurney ME, Sainz J, Thorhallsdottir M, Andresdottir M, Frigge ML, Topol EJ, Kong A, Gudnason V, Hakonarson H, Gulcher JR, Stefansson K. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Nat Genet. 2004;36:233-239.
5. Worall BB, Mychaleckyj JC. PDE4D and stroke. A real advance or a case of the Emperor's new clothes? Stroke. 2006;37:1955-1957.
6. Flossmann E, Rothwell PM. Family history of stroke in patients with transient ischemic attack in relation to hypertension and other intermediate phenotypes. Stroke. 2005;36:830-835.
7. Flossmann E, Schulz UG, Rothwell PM. Potential confounding by intermediate phenotypes in studies of the genetics of ischaemic stroke. Cerebrovasc Dis. 2005;19:1-10.
8. Barker DJ, Lackland DT. Prenatal influences on stroke mortality in England and Wales. Stroke. 2003;34:1598-1602.
9. Bushnell CD, Hurn P, Colton C, Miller VM, del Zoppo G, Elkind MS, Stern B, Herrington D, Ford-Lynch G, Gorelick P, James A, Brown CM, Choi E, Bray P, Newby LK, Goldstein LB, Simpkins J. Advancing the study of stroke in women: summary and recommendations for future research from an NINDS-Sponsored Multidisciplinary Working Group. Stroke. 2006;37:2387-2399.
10. Barker DJP. The developmental origins of adult disease. Eur J Epidemiol. 2003;18:733-736.
11. Harding JE. The nutritional basis of the fetal origins of adult disease. Int J Epidemiol. 2001;30:15-23.
12. Karter AJ, Rowell SE, Ackerson LM, Mitchell BD, Ferrara A, Selby JV, Newman B. Excess maternal transmission of type 2 diabetes. The Northern California Kaiser Permanente Diabetes Registry. Diabetes Care. 1999;22:938-943.
13. Touzé E, Rothwell PM. Heritability of ischaemic stroke in women compared with men: a genetic epidemiological study. Lancet Neurol. 2007;6:125-133.
14. Rothwell PM, Coull AJ, Silver LE, Fairhead JF, Giles MF, Lovelock CE, Redgrave JN, Bull LM, Welch SJ, Cuthbertson FC, Binney LE, Gutnikov SA, Anslow P, Banning AP, Mant D, Mehta Z. Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). Lancet. 2005;366:1773-1783.
15. Bamford J, Sandercock P, Dennis M, Warlow C, Jones L, McPherson K, Vessey M, Fowler G, Molyneux A, Hughes T, Burn J, Wade D. A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Prject 1981-86. 1. Methodology, demography and incident cases of first-ever stroke. J Neurol Neurosurg Psychiatry. 1988;51:1373-1380.
16. Armitage P, Berry G, Matthews JNS. Statistical Methods in Medical Research. Oxford: Blackwell; 2002.
17. Higgins JPT, Thmpson SG, Deeks JJ, Altman DG. Measuring inconstistency in meta-analyses. BMJ. 2003;327:560.
18. Lindgren A, Lovkvist H, Hallstrom B, Hoglund P, Jonsson AC, Kristoffersson U, Luthman H, Petersen B, Norrving B. Prevalence of stroke and vascular risk factors among first-degree relatives of stroke patients and control subjects. A prospective consecutive study. Cerebrovasc Dis. 2005;20:381-387.
19. Vitullo F, Marchioli R, Di Mascio R, Cavasinni L, Pasquale AD, Tognoni G. Family history and socioeconomic factors as predictors of myocardial infarction, unstable angina and stroke in an Italian population. PROGETTO 3A Investigators. Eur J Epidemiol. 1996;12:177-185.
20. Lisabeth LD, Kardia SL, Smith MA, Fornage M, Morgenstern LB. Family history of stroke among Mexican-American and non-Hispanic white patients with stroke and TIA: implications for the feasibility and design of stroke genetics research. Neuroepidemiology. 2005;24:96-102.
21. Tentschert S, Greisenegger S, Wimmer R, Lang W, Lalouschek W. Association of parental history of stroke with clinical parameters in patients with ischemic stroke or transient ischemic attack. Stroke. 2003;34:2114-2119.
22. Berger K, Schulte H, Stogbauer F, Assmann G. Incidence and risk factors for stroke in an occupational cohort: the PROCAM Study. Prospective Cardiovascular Muenster Study. Stroke. 1998;29:1562-1566.
23. Liao D, Myers R, Hunt S, Shahar E, Paton C, Burke G, Province M, Heiss G. Familial history of stroke and stroke risk. The Family Heart Study. Stroke. 1997;28:1908-1912.
24. Caicoya M, Corrales C, Rodriguez T. Family history and stroke: a community case-control study in Asturias, Spain. J Epidemiol Biostat. 1999;4:313-320.
25. Baweja G, Nanda NC, Parikh N, Bhatia V, Venkataraman R. Prevalence of stroke and associated risk factors in Asian Indians living in the state of Georgia, United States of America. Am J Cardiol. 2004;93:267-269.
26. Becher H, Grau A, Steindorf K, Buggle F, Hacke W. Previous infection and other risk factors for acute cerebrovascular ischaemia: attributable risks and the characterisation of high risk groups. J Epidemiol Biostat. 2000;5:277-283.
27. Alter M. Genetic factors in cerebrovascular accidents. Trans Am Neurol Assoc. 1967;92:205-208.
28. Kim H, Friedlander Y, Longstreth WT Jr, Edwards KL, Schwartz SM, Siscovick DS. Family history as a risk factor for stroke in young women. Am J Prev Med. 2004;27:391-396.
29. Lindenstrom E, Boysen G, Nyboe J. Risk factors for stroke in Copenhagen, Denmark. I. Basic demographic and social factors. Neuroepidemiology. 1993;12:37-42.
30. Reed T, Kirkwood SC, DeCarli C, Swan GE, Miller BL, Wolf PA, Jack LM, Carmelli D. Relationship of family history scores for stroke and hypertension to quantitative measures of white-matter hyperintensities and stroke volume in elderly males. Neuroepidemiology. 2000;19:76-86.
31. MacClellan LR, Mitchell BD, Cole JW, Wozniak MA, Stern BJ, Giles WH, Brown DW, Sparks MJ, Kittner SJ. Familial aggregation of ischemic stroke in young women: the stroke prevention in young women study. Genet Epidemiol. 2006;30:602-608.
32. Gifford AJ. An epidemiological study of cerebrovascular disease. Am J Public Health. 1966;56:452-461.
33. Marshall J. Familial incidence of cerebrovascular disease. J Med Gen. 1971;8:84-89.
34. Starr J, Rush M, De Mey R, Dennis M. Parental causes of death in stroke. Cerebrovasc Dis. 2001;11:65-70.
35. Welin L, Svardsudd K, Wilhelmsen L, Larsson B, Tibblin G. Analysis of risk facotors for stroke in a cohort of men born in 1913. N Engl J Med. 1987;317:521-526.
36. Jousilahti P, Rastenyte D, Tuomilehto J, Sarti C, Vartiainen E. Parental history of cardiovascular disease and risk of stroke: A prospective follow-up of 14 371 middle-aged men and women in Finland. Stroke. 1997;28:1361-1366.
37. Gertler MM, Rusk HA, Whiter HH, Leetma HE, Ehrenkranz M. Ischemic cerebrovascular disease. The assessment of risk factors. Geriatrics. 1968;23:135-141.
38. Rothwell PM, Coull AJ, Giles MF, Howard SC, Silver LE, Bull LM, Gutnikov SA, Edwards P, Mant D, Sackley CM, Farmer A, Sandercock PA, Dennis MS, Warlow CP, Bamford JM, Anslow P. Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet. 2004;363:1925-1933.
39. Feigin VL, Lawes CM, Bennett DA, Anderson CS. Stroke epidemiology: a review of population-based studies of incidence, prevalence, and casefatality in the late 20th century. Lancet Neurol. 2003;2:43-53.
40. Kiely DK, Wolf PA, Cupples LA, Beiser AS, Myers RH. Familial aggregation of stroke. The Framingham Study. Stroke. 1993;24:1366-1371.
41. Drake AJ, Walker BR. The intergenerational effects of fetal programming: non-genomic mechanisms for the inheritance of low birth weight and cardiovascular risk. J Endocrinol. 2004;180:1-16.
42. Dabelea D, Hanson RL, Lindsay RS, Pettitt DJ, Imperatore G, Gabir MM, Roumain J, Bennett PH, Knowler WC. Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships. Diabetes. 2000;49:2208-2211.
43. DeStefano AL, Gavras H, Heard-Costa N, Bursztyn M, Manolis A, Farrer LA, Baldwin CT, Gavras I, Schwartz F. Maternal component in the familial aggregation of hypertension. Clin Genet. 2001;60:13-21.
44. Poulsen P, Vaag A, Kyvik K, Beck-Nielsen H. Genetic versus environmental aetiology of the metabolic syndrome among male and female twins. Diabetologia. 2001;44:537-543.
45. Sundquist K, Li X. Differences in maternal and paternal transmission of coronary heart disease. Am J Prev Med. 2006;30:480-486.
46. Jiang YH, Bressler J, Beaudet AL. Epigenetics and human disease. Annu Rev Genomics Hum Genet. 2004;5:479-510.
47. Weaver IC, Cervoni N, Champagne FA, D'Alessio AC, Sharma S, Seckl JR, Dymov S, Szyf M, Meaney MJ. Epigenetic programming by maternal behavior. Nat Neurosci. 2004;7:847-854.
48. Kovtun IV, Therneau TM, McMurray CT. Gender of the embryo contributes to CAG instability in transgenic mice containing a Huntington's disease gene. Hum Mol Genet. 2000;9:2767-2775.
49. Cameron NM, Champagne FA, Parent C, Fish EW, Ozaki-Kuroda K, Meaney MJ. The programming of individual differences in defensive responses and reproductive strategies in the rat through variations in maternal care. Neurosci Biobehav Rev. 2005;29:843-865.
50. Barker DJ. Fetal origins of coronary heart disease. BMJ. 1995;311:171-174.
51. Singhal A, Lucas A. Early origins of cardiovascular disease: is there a unifying hypothesis? Lancet. 2004;363:1642-1645.
52. Chang ET, Smedby KE, Hjalgrim H, Glimelius B, Adami HO. Reliability of self-reported family history of cancer in a large case-control study of lymphoma. J Natl Cancer Inst. 2006;98:61-68.
53. Murabito JM, Nam BH, D'Agostino RB Sr, Lloyd-Jones DM, O'Donnell CJ, Wilson PW. Accuracy of offspring reports of parental cardiovascular disease history: the Framingham Offspring Study. Ann Intern Med. 2004;140:434-440.
54. Thorand B, Liese AD, Metzger MH, Reitmeir P, Schneider A, Lowel H. Can inaccuracy of reported parental history of diabetes explain the maternal transmission hypothesis for diabetes? Int J Epidemiol. 2001;30:1084-1089.
55. Meschia JF, Case LD, Worrall BB, Brown RD Jr, Brott TG, Frankel M, Silliman S, Rich SS. Family history of stroke and severity of neurologic deficit after stroke. Neurology. 2006;67:1396-1402.