Inferential testing for linkage with GENEHUNTER-MODSCORE: The impact of the pedigree structure on the null distribution of multipoint MOD scores

Genetic Epidemiology

Volumn 32, Issue 1, 2008, Pages 73-83

  Mattheisen, Manuel ^a   Dietter, Johannes ^b   Knapp, Michael ^a   Baur, Max P ^a   Strauch, Konstantin ^b  

^a UNIVERSITY OF BONN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Likelihood; Maximization; Monte Carlo simulation; Parametric analysis; Significance; Trait model; Type I error

Indexed keywords

ARTICLE; COMPUTER SIMULATION; INFERENTIAL STATISTICS; LINKAGE ANALYSIS; MONTE CARLO METHOD; NULL HYPOTHESIS; PARAMETRIC TEST; PEDIGREE; SCORING SYSTEM;

CHROMOSOME MAPPING; COMPUTER SIMULATION; FEMALE; HUMANS; LINKAGE (GENETICS); LOD SCORE; MALE; METHODS; MODELS, GENETIC; PEDIGREE; RECOMBINATION, GENETIC;

EID: 38149051548     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20264     Document Type: Article

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