Transcriptional changes in human Caco-2 colon cancer cells following exposure to a recurrent non-toxic dose of polyphenol-rich chokeberry juice

Genes and Nutrition

Volumn 2, Issue 1, 2007, Pages 111-113

  Bermudez Soto M J ^a   Larrosa, M ^a   Garcia Cantalejo J ^b   Espin J C ^a   Tomas Barberan F A ^a   Garcia Conesa M T ^a  

^a RESEARCH GROUP ON QUALITY   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Aronia Melanocarpa; Caco 2; Chokeberry; Colon cancer; Gene expression; Microarrays; Polyphenols

Indexed keywords

POLYPHENOL;

APOPTOSIS; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN CACO 2; CHOKEBERRY JUICE; COLON CANCER; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG MECHANISM; FRUIT JUICE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PHARMACOGENETICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALIA; PHOTINIA; PHOTINIA MELANOCARPA;

EID: 38149041781     PISSN: 15558932     EISSN: 18653499     Source Type: Journal    
DOI: 10.1007/s12263-007-0026-5     Document Type: Conference Paper

References (9)

1. Bérmudez-Soto MJ, Tomás-Barberán FA (2004) Evaluation of commercial red fruit juice concentrates as ingredients for antioxidant functional juices. Eur Food Res Technol 219:133-141
2. Galvano F, La Fauci L et al (2004) Cyanidins: metabolism and biological properties. J Nutr Biochem 15:2-11
3. Bagchi D et al (2004) Anti-angiogenic, antioxidant, and anti-carcinogenic properties of a novel anthocyanin-rich berry extract formula. Biochemistry (Moscow) 69:75-80
4. Barnes S, Allison DB (2004) Excitement and realities in microarrays analysis of the biological effects of polyphenols. Pharm Biol 42:94-101
5. Bermúdez-Soto MJ, Tomás-Barberán FA, García-Conesa MT (2007) Stability of polyphenols in chokeberry (Aronia melanocarpa) subjected to in vitro gastric and pancreatic digestion. Food Chem 102(3):865-874
6. Nittka S, Günter J, Ebisch C, Erbersdobler A, Neumaier M (2004) The human tumor suppressor CEACAM1 modulates apoptosis and is implicated in early colorectal tumorigenesis. Oncogene 23:9306-9313
7. Hardwick JC, Van den Brink GR, Bleuming SA, Ballester I, Van den Brande JM, Keller JJ, Offerhaus GJ, Van Deventer SJ, Peppelenbosch MP (2004) Bone morphogenetic protein 2 is expressed by, and acts upon, mature epithelial cells in the colon. Gastroenterology 126:111-121
8. Thiery JP (2001) Role of growth factor signalling in epithelial plasticity during development and in carcinogenesis. Bull Acad Natl Med 185:1279-1292
9. Andersen K, Smith-Sorensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad O, Maelandsmo GM (2003) Interferon-gamma suppresses SI00A4 transcription independently of apoptosis or cell cycle. Br J Cancer 88:1995-2001