Acute renal allograft rejection is associated with increased levels of vascular endothelial growth factor in the urine

Nephrology

Volumn 13, Issue 1, 2008, Pages 73-79

  Peng, Wenhan ^a   Chen, Jianghua ^a,b   Jiang, Yuguang ^a   Shou, Zhangfei ^a,b   Chen, Ying ^a   Wang, Huiping ^a,b  

^a ZHEJIANG UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

Author keywords

Rejection; Transplantation; Urine; Vascular endothelial growth factor

Indexed keywords

CREATININE; STEROID; VASCULOTROPIN;

ACUTE DISEASE; ACUTE KIDNEY TUBULE NECROSIS; ADULT; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; KIDNEY ALLOGRAFT REJECTION; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; ROC CURVE; SENSITIVITY AND SPECIFICITY; URINALYSIS;

ACUTE DISEASE; ADULT; BIOLOGICAL MARKERS; BIOPSY; DIAGNOSIS, DIFFERENTIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; HUMANS; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; PROGNOSIS; RETROSPECTIVE STUDIES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 38149032628     PISSN: 13205358     EISSN: 14401797     Source Type: Journal    
DOI: 10.1111/j.1440-1797.2007.00856.x     Document Type: Article

References (36)

1. Cosio FG, Pelletier RP, Sedmak DD et al. Renal allograft survival following acute rejection correlates with blood pressure levels and histopathology. Kidney Int. 1999 56 : 1912 19.
2. Meier-Kriesche HU, Schold JD, Srinivas TR, Kaplan B. Lack of improvement in renal allograft survival despite a marked decrease in acute rejection rates over the most recent era. Am. J. Transplant 2004 4 : 378 83.
3. Beckingham IJ, Nicholson ML, Bell PR. Analysis of factors associated with complications following renal transplant needle core biopsy. Br. J. Urol. 1994 73 : 13 18.
4. Fogazzi GB, Garigali G. The clinical art and science of urine microscopy. Curr. Opin. Nephrol. Hypertens. 2003 12 : 625 32.
5. Thongboonkerd V, Mcleish KR, Arthur JM, Klein JB. Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int. 2002 62 : 1461 9.
6. Pieper R., Gatlin CL, Mcgrath AM et al. Characterization of the human urinary proteome: a method for high-resolution display of urinary proteins on two-dimensional electrophoresis gels with a yield of nearly 1400 distinct protein spots. Proteomics 2004 4 : 1159 74.
7. O'Riordan E, Orlova TN, Mei JF et al. Bioinformatic analysis of the urine proteome of acute allograft rejection. J. Am. Soc. Nephrol. 2004 15 : 3240 8.
8. Voshol H, Brendlen N, Muller D et al. Evaluation of biomarker discovery approaches to detect protein biomarkers of acute renal allograft rejection. Proteomics 2005 4 : 1192 9.
9. Hauser IA, Spiegler S, Kiss E et al. Prediction of acute renal allograft rejection by urinary monokine induced by IFN-γ (MIG). J. Am. Soc. Nephrol. 2005 16 : 1849 58.
10. Tatapudi RR, Muthukumar T, Dadhania D et al. Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int. 2004 65 : 2390 97.
11. Muthukumar T, Dadhania D, Ding R. et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N. Engl. J. Med. 2005 353 : 2342 51.
12. Ferrara N, Houck KA, Jakeman LB, Winer J, Leung DW. The vascular endothelial growth factor family of polypeptides. J. Cell Biochem. 1991 47 : 211 18.
13. Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999 13 : 9 22.
14. Tinckam KJ, Djurdjev O, Magil AB. Glomerular moncytes predict worse outcomes after acute renal allograft rejection independent of C4d status. Kidney Int. 2005 68 : 1866 74.
15. Detmar M, Brown LF, Schon MP et al. Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J. Invest. Dermatol. 1998 111 : 1 6.
16. Marumo T, Schini-Kerth VB, Busse R. vascular endothelial growth factor activates nuclear factor kappa B and induced monocyte chemoattractant protein-1 in bovine retinal endothelial cells. Diabetes 1999 48 : 1131 7.
17. Kim I, Moon SO, Kim SH, Koh YS, Koh GY. VEGF stimulates expression of ICAM-1, VCAM-1 and E-Selectin through nuclear factor kappa B activation in endothelial cells. J. Biol. Chem. 2001 276 : 7614 20.
18. Wu JY, Chen JH, Wang YM et al. Improved clinical outcomes in Chinese renal allograft recipients receiving lower dose immunosuppressants. Transplantation 2004 78 : 713 18.
19. Racusen LC, SoleZ. K, Colvin RB et al. The Banff 97 working classification of renal allograft pathology. Kidney Int. 1999 55 : 713 23.
20. Racusen LC, SoleZ. K, Colvin RB et al. Antibody-mediated rejection criteria - an addition to the Banff 97 classification of renal allograft rejection. Am. J. Transplant 2003 3 : 708 14.
21. Janghua C, Wenqing X, Huiping W et al. C4d as a significant predictor for humoral rejection in renal allografts. Clin. Transplant. 2005 19 : 785 91.
22. Sarwal MM, Jani A, Chang S et al. Granulysin expression is a marker for acute rejection and steroid resistance in human renal transplantation. Hum. Immunol. 2001 62 : 21 31.
23. Lederer SR, Friedrich N, Regenbogen C, Getto R., Toepfer M, Sitter T. Non-invasive monitoring of renal transplant recipients: urinary excretion of soluble adhesion molecules and of the complement-split product C4d. Nephron Clin. Pract. 2003 94 : 19 26.
24. Lazzeri E, Rotondi M, Mazzinghi B et al. High CXCL10 expression in rejected kidneys and predictive role of pretransplant serum CXCL10 for acute rejection and chronic allograft nephropathy. Transplantation 2005 79 : 1215 20.
25. Avihingsanon Y, Phumesin P, Benjachat T et al. Measurement of urinary chemokine and growth factor messenger RNAs: a noninvasive monitoring in lupus nephritis. Kidney Int. 2006 69 : 747 53.
26. Harris KR, Nicholas JD, Lee HA. Serum C-reactive protein a useful and economical marker of immune activation in renal transplantation. Transplantation 1996 61 : 1593 7.
27. Reek C, Conrad S, Tenschert W, Huland H. Do serum C-reactive protein measurements help to discriminate episodes of renal dysfunction in patients after renal transplantation? Clin. Chim. Acta 2001 310 : 57 61.
28. Arora S, Gullestad L, Wergeland R. et al. Probrain natriuretic peptide and c-reactive protein as markers of acute rejection, allograft vasculopathy, and mortality in heart transplantation. Transplantation 2007 83 : 1308 15.
29. Steinhoff J, Einecke G, Niederstadt C et al. Renal graft rejection or urinary tract infection? The value of myeloperoxidase, C-reactive protein, and α2-macroglobulin in the urine. Transplantation 1997 64 : 443 7.
30. Ferrara N, Gerber HP. The role of vascular endothelial growth factor in angiogenesis. Acta Haematol. 2001 106 : 148 56.
31. Whittle C, Gillespie K, Harrison R. et al. Heterogeneous (VEGF) isoform mRNA and receptor mRNA expression in human glomeruli, and the identification of VEGF148 mRNA, a novel truncated splice variant. Clin. Sci. 1999 97 : 303 12.
32. Rintala SE, Savikko J, Rintala JM et al. Vascular endothelial growth factor (VEGF) ligand and receptor induction in rat renal allograft rejection. Transplant. Proc. 2006 38 : 3236 8.
33. Xiong M, Elson G, Legarda D, Leibovich SJ. Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthesis pathway. Am. J. Pathol. 1998 153 : 587 98.
34. Sunderkotter C, Steinbrink K, Goebeler M, Bhardwaj R, Sorg C. Macrophage and angiogenesis. J. Leukoc. Biol. 1994 55 : 410 12.
35. Shahbazi M, Fryer AA, Pravica V et al. Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection. J. Am. Soc. Nephrol. 2002 13 : 260 64.
36. Watson CJ, Webb NJ, Bottomley MJ et al. Identification of polymorphism within the vascular endothelial growth factor (VEGF) gene: correlation with variation in VEGF protein production. Cytokine 2000 12 : 1232 5.