Use of target controlled infusion to derive age and gender covariates for propofol clearance

Clinical Pharmacokinetics

Volumn 47, Issue 2, 2008, Pages 119-127

  White, Martin ^a   Kenny, Gavin N C ^b   Schraag, Stefan ^c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b GLASGOW ROYAL INFIRMARY   (United Kingdom)

^c GOLDEN JUBILEE NATIONAL HOSPITAL   (United Kingdom)

Author keywords

Age differences; Gender differences; Metabolic clearance rate; Pharmacokinetic modelling; Propofol, pharmacokinetics

Indexed keywords

ALFENTANIL; PROPOFOL;

ACCURACY; ADOLESCENT; ADULT; AGE; AGED; ARTICLE; BLOOD SAMPLING; CONTINUOUS INFUSION; COVARIANCE; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; ELECTIVE SURGERY; FEMALE; GENDER; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; NORMAL DISTRIBUTION; PRIORITY JOURNAL; VENOUS BLOOD;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ALGORITHMS; ANALYSIS OF VARIANCE; ANESTHETICS, INTRAVENOUS; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INPATIENTS; KINETICS; MALE; METABOLIC CLEARANCE RATE; MIDDLE AGED; MODELS, BIOLOGICAL; PROPOFOL; SEX FACTORS; TIME FACTORS;

EID: 38149029126     PISSN: 03125963     EISSN: 03125963     Source Type: Journal    
DOI: 10.2165/00003088-200847020-00005     Document Type: Article

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