Gender differences in the pharmacokinetics of propofol in elderly patients during and after continuous infusion

British Journal of Anaesthesia

Volumn 86, Issue 2, 2001, Pages 183-188

  Vuyk, J ^a   Oostwouder, C J ^a   Vletter, A A ^a   Burm, A G L ^a   Bovill, J G ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Age factors; Anaesthetic techniques, i.v., pharmacokinetics, propofol; Anaesthetics, i.v., alfentanil; Anaesthetics, i.v., propofol; Gender factors

Indexed keywords

ALFENTANIL; GELATIN SUCCINATE; METHADONE; MIDAZOLAM; OPIATE; OXYGEN; PARACETAMOL; PROPOFOL; REMIFENTANIL; SUFENTANIL; TEMAZEPAM; THIOPENTAL; VECURONIUM;

AGE; AGED; AIR; ARTERIAL BLOOD; ARTICLE; ARTIFICIAL VENTILATION; BLOOD SAMPLING; CLINICAL ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; COVARIANCE; DOSE TIME EFFECT RELATION; DRUG CLEARANCE; FEMALE; GENDER; GENERAL SURGERY; HUMAN; LEAN BODY WEIGHT; MALE; MULTIPLE REGRESSION; PARAMETER; PRIORITY JOURNAL; SEX DIFFERENCE;

EID: 0035143454     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/86.2.183     Document Type: Article

References (14)

1. Effect of age on propofol pharmacokinetics
2. The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers
3. Population pharmacokinetics of propofol
4. First-pass lung uptake and pulmonary clearance of propofol. Assessment with a recirculatory indocyanine green model
5. Alfentanil modifies the pharmacokinetics of propofol in volunteers
6. Gender differences in autonomic functions associated with blood pressure regulation
7. Women emerge from general anesthesia with propofol/alfentanil/nitrous oxide faster than men
8. Effect of age, gender and obesity on midazolam kinetics
9. Population pharmacokinetics and pharmacodynamics of thiopental: The effect of age revisited
10. Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development
11. Linearity of pharmacokinetics and model estimation of sufentanil
12. Population pharmacokinetics of alfentanil: The average dose-plasma concentration relationship and interindividual variability in patients
13. Pharmacokinetic model driven infusion of propofol in children
14. The influence of age on propofol pharmacodynamics