Improvement in adult height after growth hormone treatment in adolescents with short stature born small for gestational age: Results of a randomized controlled study

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 4, 2003, Pages 1587-1593

  Carel, Jean Claude ^a,d   Chatelain, Pierre ^b   Rochiccioli, Pierre ^c   Chaussain, Jean Louis ^a  

^a INSERM   (France)

^b HÔPITAL DEBROUSSE   (France)

^c HÔPITAL DES ENFANTS   (France)

^d Grp Hosp Cochin S Vincent de Paul ^*  (France)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE;

ADOLESCENT; ARTICLE; BODY HEIGHT; CATCH UP GROWTH; CHILD; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SHORT STATURE; SMALL FOR DATE INFANT; TREATMENT OUTCOME;

ADOLESCENT; BODY HEIGHT; CHILD; FEMALE; HUMAN GROWTH HORMONE; HUMANS; INFANT, NEWBORN; INFANT, SMALL FOR GESTATIONAL AGE; INSULIN-LIKE GROWTH FACTOR I; MALE; TIME FACTORS; TREATMENT OUTCOME;

EID: 0038699006     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021123     Document Type: Article

References (40)

1. Albertsson-Wikland K, Karlberg J 1994 Natural growth in children born small for gestational age with and without catch-up growth. Acta Paediatr Suppl 399:64-70
2. Luo ZC, Karlberg J 2000 Critical growth phases for adult shortness. Am J Epidemiol 152:125-131
3. Leger J, Levy-Marchal C, Bloch J, Pinet A, Chevenne D, Porquet D, Collin D, Czernichow P 1997 Reduced final height and indications for insulin resistance in 20 year olds born small for gestational age: regional cohort study. BMJ 315:341-347
4. de Zegher F, François I, van Helvoirt M, Beckers D, Chatelain P 1998 Growth hormone treatment of short children born small for gestational age. Trends Endocrinol Metab 9:233-237
5. Tanner JM, Ham TJ 1969 Low birthweight dwarfism with asymmetry (Silver's syndrome): treatment with human growth hormone. Arch Dis Child 44:231-243
6. Chatelain P, Job J-C, Blanchard J, Ducret JP, Olivier M, Sagnard L, Vanderschueren-Lodeweyckx M 1994 Dose-dependent catch-up growth after 2 years of growth hormone treatment in intrauterine growth-retarded children. J Clin Endocrinol Metab 78:1454-1460
7. de Zegher F, Francois I, van Helvoirt M, Van den Berghe G 1997 Small as fetus and short as child: from endogenous to exogenous growth hormone. J Clin Endocrinol Metab 82:2021-2026
8. Root AW 1998 Does growth hormone have a role in the management of children with nongrowth hormone deficient short stature and intrauterine growth retardation. J Clin Endocrinol Metab 83:1067-1069
9. Oberfield SE 1999 Growth hormone use in normal, short children-a plea for reason. N Engl J Med 340:557-559
10. Donaldson M 2001 What is the role of growth-hormone therapy in short children who were small for gestational age? Lancet 358:347-348
11. Job J-C, Chaussain JL, Job B, Ducret JP, Maes M, Olivier M, Ponte C, Rochiccioli P, Vanderschueren-Lodeweyckx M, Chatelain P 1996 Follow-up of three years of treatment with growth hormone and of one post-treatment year in children with severe growth retardation of intrauterine onset. Pediatr Res 39:354-359
12. de Zegher F, Albertsson-Wikland K, Wollmann HA, Chatelain P, Chaussain JL, Lofstrom A, Jonsson B, Rosenfeld RG 2000 Growth hormone treatment of short children born small for gestational age: growth responses with continuous and discontinuous regimens over 6 years. J Clin Endocrinol Metab 85:2816-2821
13. Rosilio M, Carel JC, Blazy D, Chaussain JL 1997 Growth hormone treatment of children with short stature secondary, to intra-uterine growth retardation: effect of 2 years' treatment and 2 years' follow-up. Horm Res 48(Suppl 4):23-28
14. Sas T, de Waal W, Mulder P, Houdijk M, Jansen M, Reeser M, Hokken-Koelega A 1999 Growth hormone treatment in children with short stature born small for gestational age: 5-year results of a randomized, double-blind, dose-response trial. J Clin Endocrinol Metab 84:3064-3070
15. McCaughey ES, Mulligan J, Voss LD, Betts PR 1998 Randomised trial of growth hormone in short normal girls. Lancet 351:940-944
16. Buchlis JG, Irizarry L, Crotzer BC, Shine BJ, Allen L, MacGillivray MH 1998 Comparison of final heights of growth hormone-treated vs. untreated children with idiopathic growth failure. J Clin Endocrinol Metab 83:1075-1079
17. Hintz RL, Attie KM, Baptista J, Roche A; the Genentech Collaborative Group 1999 Effect of growth hormone treatment on adult height of children with idiopathic short stature. N Engl J Med 340:502-507
18. Wit JM, Rekers-Mombarg LTM 2002 Final height gain by GH therapy in children with idiopathic short stature is dose dependent. J Clin Endocrinol Metab 87:604-611
19. Guyda HJ 1999 Commentary. Four decades of growth hormone therapy for short children: what have we achieved? J Clin Endocrinol Metab 84:4307-4316
20. Reiter EO, Lee PA 2002 Delayed puberty. Adolesc Med 13:101-118
21. Coutant R, Carel JC, Letrait M, Bouvattier C, Chatelain P, Coste J, Chaussain JL 1998 Short stature associated with intrauterine growth retardation: final heights of untreated and growth hormone treated children. J Clin Endocrinol Metab 83:1070-1074
22. Ranke MB, Lindberg A 1996 Growth hormone treatment of short children born small for gestational age or with Silver-Russell syndrome: results from KIGS (Kabi International Growth Study), including the first report on final height. Acta Paediatr Suppl 417:18-26
23. Usher R, McLean F 1969 Intrauterine growth of live-born Caucasian infants at sea level: standards obtained from measurements in 7 dimensions of infants born between 25 and 44 weeks of gestation. J Pediatr 74:901-910
24. Sempé M, Pédron G, Roy P 1979 Auxologie, méthodes et séquences. Paris: Théraplix
25. Greulich WW, Pyle SI 1959 Radiographic atlas of skeletal development of the hand and wrist. Stanford, CA: Stanford University Press 1959.
26. Marshall WA, Tanner JM 1969 Variations in the pattern of pubertal changes in girls. Arch Dis Child 44:291-303
27. Marshall WA, Tanner JM 1970 Variations in the pattern of pubertal changes in boys. Arch Dis Child 45:13-24
28. Bayley N, Pinneau S 1952 Tables for predicting adult height from skeletal age. J Pediatr 14:432-441
29. Blethen SL, Baptista J, Kuntze J, Foley T, LaFranchi S, Johanson A 1997 Adult height in growth hormone (GH)-deficient children treated with biosynthetic GH. The Genentech Growth Study Group. J Clin Endocrinol Metab 82:418-420
30. Edwards IR, Aronson JK 2000 Adverse drug reactions: definitions, diagnosis, and management. Lancet 356:1255-1259
31. Chatelain PG, van Wijk PA, Copeland KC, Blethen SL, Underwood LE 1983 Effect of in vitro action of serum proteases or exposure to acid on measurable immunoreactive somatomedin-C in serum. J Clin Endocrinol Metab 56:376-383
32. Carel JC, Ecosse E, Nicolino M, Tauber M, Leger J, Cabrol S, Bastié-Sigeac I, Chaussain JL, Coste J 2002 Adult height after long-term recombinant growth hormone treatment for idiopathic isolated growth hormone deficiency: observational follow-up study of the French population-based registry. BMJ 325:70-73
33. Coste J, Letrait M, Carel JC, Tresca J-P, Chatelain P, Rochiccioli P, Chaussain JL, Job J-C 1997 Long-term results of GH treatment in short stature children: a population register-based study. BMJ 315:708-713
34. SAS Institute Inc 1990 SAS user's guide statistics, 6th ed. Cary, NC: SAS Institute Inc
35. Price DA 1996 Spontaneous adult height in patients with idiopathic short stature. Horm Res 45(Suppl 2):59-63
36. de Zegher F, Du Caju MV, Heinrichs C, Maes M, De Schepper J, Craen M, Vanweser K, Malvaux P, Rosenfeld RG 1999 Early, discontinuous, high dose growth hormone treatment to normalize height and weight of short children born small for gestational age: results over 6 years. J Clin Endocrinol Metab 84:1558-1561
37. Voss LD 2001 Short normal stature and psychosocial disadvantage: a critical review of the evidence. J Pediatr Endocrinol Metab 14:701-711
38. Downie AB, Mulligan J, Stratford RJ, Betts PR, Voss LD 1997 Are short normal children at a disadvantage? The Wessex Growth Study. BMJ 314:97-100
39. Pasquino AM, Pucarelli I, Roggini M, Segni M 2000 Adult height in short normal girls treated with gonadotropin-releasing hormone analogs and growth hormone. J Clin Endocrinol Metab 85:619-622
40. Wickman S, Sipila I, Ankarberg-Lindgren C, Norjavaara E, Dunkel L 2001 A specific aromatase inhibitor and potential increase in adult height in boys with delayed puberty: a randomised controlled trial. Lancet 357:1743-1748