Development of an RP-HPLC method for the analysis of phenolic compounds in Achillea millefolium L.

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 4, 2008, Pages 596-610

  Benetis, Raimondas ^a   Radušiene, Jolita ^b   Jakštas, Valdas ^a   Janulis, Valdimaras ^a   Malinauskas, Faustas ^a  

^a KAUNAS UNIVERSITY OF MEDICINE   (Lithuania)

^b INSTITUTE OF BOTANY   (Lithuania)

Author keywords

Achillea millefolium; Extraction; HPLC; Phenolics

Indexed keywords

ACHILLEA MILLEFOLIUM; EXTRACTANT; PHENOLCARBONIC ACID; PHENOLICS;

ETHANOL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLANTS (BOTANY); SAMPLING; SOLVENT EXTRACTION; SONICATION;

PHENOLIC RESINS;

ACHILLEA MILLEFOLIUM EXTRACT; ALCOHOL; APIGENIN; APIGETRIN; CARBONIC ACID DERIVATIVE; CHLOROGENIC ACID; FLAVONOID; LUTEOLIN; LUTEOLIN 7 GLUCOSIDE; PHENOL DERIVATIVE; RUTOSIDE; UNCLASSIFIED DRUG; VICENIN 2;

ACHILLEA; ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); PHOTODIODE ARRAY DETECTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLVENT EFFECT; SOLVENT EXTRACTION; ULTRASOUND; ULTRAVIOLET RADIATION;

ACHILLEA; ACHILLEA MILLEFOLIUM;

EID: 38049143819     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070701815247     Document Type: Article

References (34)

1. Si, X.T.; Zhang, M.L.; Shi, Q.W.; Kiyota, H. Chemical constituents of the plants in the genus Achillea. Chem. Biodivers. 2006, 3 (11), 1163-1180.
2. Barnes, J.; Anderson, L.A.; Phillipson, J.D. Herbal Medicines; Pharmaceutical Press: London, Chicago, 2002; 489-491.
3. Blumenthal, M.; Goldberg, A.; Brinckmann, J. Herbal Medicine. Expanded Commission E Monographs; Integrative Medicine Communications: Newton, 2000; 419-423.
4. Aljancic, I.; Vajs, V.; Menkovic, N.; Karadzic, I.; Juranic, N.; Milosavljevic, S.; Macura, S. Flavones and sesquiterpene lactones from Achillea atrata subsp. multifida: antimicrobial activity. Nat. Prod. 1999, 62 (6), 909-911.
5. Garcia, M.D.; Puerta, R.; Martinez, S.; Saenz, N.T. Analgesic antipyretic antiinflammatory effects of Achillea ageratum. Phytother. Res. 1997, 11 (5), 376-379.
6. Benedek, B.; Geisz, N.; Jager, W.; Thalhammer, T.; Kopp, B. Choleretic effects of yarrow (Achillea millefolium s.l.) in the isolated perfused rat liver. Phytochemistry 2006, 13 (9-10), 702-706.
7. Trifunovic, S.; Vajs, V.; Juranic, Z.; Zizac, Z.; Tesevic, V.; Macura, S.; Milosavljevic, S. Cytotoxic constituents of Achillea clavennae from Montenegro. Phytochemistry 2006, 67 (9), 887-893.
8. Haidara, K.; Zamir, L.; Shi, Q.W.; Batist, G. The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action. Cancer. Lett. 2006, 242 (2), 180-190.
9. Innocenti, G.; Vegeto, E.; Dall'acqua, S.; Ciana, P.; Giorgetti, M.; Agradi, E.; Sozzi, A.; Fico, G.; Tome, F. In vitro estrogenic activity of Achillea millefolium L. Phytomedicine 2007, 14 (2-3), 147-152.
10. Havsteen, B.H. The biochemistry and medical significance of the flavonoids. Pharmacol. Ther. 2002, 96 (2-3), 67-202.
11. Ziakova, A.; Brandsteterova, E. Validation of HPLC Determination of Phenolic Acids Present in Some Lamiaceae Family Plants. J. Liq. Chromatogr. & Rel. Technol. 2003, 26 (3), 443-453.
12. Grace, S.C.; Logan, B.A. Energy dissipation and radical scavenging by the plant phenylpropanoid pathway. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2000, 355 (1402), 1499-1510.
13. Dokhani, S.; Cottrell, T.; Khajeddin, J.; Mazza, G. Analysis of aroma and phenolic components of selected Achillea species. Plant. Foods. Hum. Nutr. 2005, 60 (2), 55-62.
14. Ardestani, A.; Yazdanparast, R. Antioxidant and free radical scavenging potential of Achillea santolina extracts. Food Chem. 2007, 104 (1), 21-29.
15. Nickavar, B.; Kamalinejad, M.; Haj-Yahya, M.; Shafaghi, B. Comparison of the free radical scavenging activity of six iranian Achillea species. Pharmaceut. Biol. 2006, 44 (3), 208-212.
16. Gherase, F.; Miron, A.; Zagnat, M.; Hancianu, M.; Stanescu, U.; Grigorescu, E. Phytochemical investigations regarding the flavonoidic compounds of some species belonging to the Achillea millefolium L. group. Rev. Med. Chir. Soc. Med. Nat. Iasi. 2004, 108 (1), 177-180.
17. Srinivasa, H.; Bagul, M.S.; Padh, H.; Rajani, M. A rapid densitometric method for the quantification of luteolin in medicinal plants using HPTLC. Chromatographia 2004, 60 (1-2), 131-134.
18. Marchart, E.; Kopp, B. Capillary electrophoretic separation and quantification of flavone-O- and C-glycosides in Achillea setacea W. et K. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2003, 792 (2), 363-368.
19. Marchart, E.; Hattenberger, A.; Krenn, L.; Kopp, B. Analysis of flavonoids in Achillea nobilis L. by capillary electrophoresis. Sci. Pharm. 2003, 71 (2), 133-144.
20. Benedek, B.; Gjoncaj, N.; Saukel, J.; Kopp, B. Distribution of phenolic compounds in middleeuropean taxa of the Achillea millefolium L. Aggregate. Chem. Biodivers. 2007, 4 (5), 849-857.
21. Andersen, O.M.; Markham, K.R. Flavonoids: Chemistry, Biochemistry and Applications; CRC Press Taylor & Francis Group: Boca Raton, USA, 2006; 2-16.
22. Naczk, M.; Shahidi, F. Extraction and analysis of phenolics in food. J. Chromatogr. A 2004, 1054 (1-2), 95-111.
23. Cimpan, G.; Gocan, S. Analysis of medicinal plants by HPLC: recent approaches. J. Liq. Chromatogr. & Rel. Technol. 2002, 25 (13-15), 2225-2292.
24. Urbonaviciute, A.; Jakstas, V.; Kornysova, O.; Janulis, V.; Maruska, A. Capillary electrophoretic analysis of flavonoids in single-styled hawthorn (Crataegus monogyna Jacq.) ethanolic extracts. J. Chromatogr. A 2006, 1112 (1-2), 339-344.
25. Molnar-Perl, I.; Fuzfai, Z. Chromatographic, capillary electrophoretic and capillary electrochromatographic techniques in the analysis of flavonoids. J. Chromatogr. A 2005, 1073 (1-2), 201-227.
26. Snyder, L.R.; Kirkland, J.J.; Glajch, J.L. Practical HPLC Method Development; John Wiley & Sons: New York, 1997; 144-155.
27. Ahuja, S.; Dong, M.W. Handbook of Pharmaceutical Analysis by HPLC (Separation Science and Technology; Elsevier Academic Press: London, UK, 2005; Vol. 6, 35-37.
28. Gritti, F.; Guiochon, G. A chromatographic estimate of the degree of surface heterogeneity of RPLC packing materials. III. Endcapped amido-embedded reversed phase. J. Chromatogr. A 2006, 1103 (1), 69-82.
29. Radusiene, J.; Gudaityte, O. Distribution of proazulenes in Achillea millefolium s.l. wild populations in relation to phytosociological dependence and morphological characters. Plant Genet. Resour. 2005, 3 (2), 136-143.
30. Radusiene, J.; Janulis, V. Improvement of diversity, trade and conservation of medicinal and aromatic plants. Medicina (Kaunas) 2004, 40 (8), 705-709.
31. Kasaj, D.; Krenn, L.; Prinz, S.; Hufner, A.; Haslinger, E.; Yu, S.S.; Kopp, B. Flavon- and flavonolglycosides from Achillea pannonica Scheele. Z Naturforsch [C] 2001, 56 (7-8), 521-525.
32. Aherne, S.A.; O'Brien, N.M. Dietary flavonols: chemistry, food content, and metabolism. Nutrition 2002, 18 (1), 75-81.
33. Tattini, M.; Guidi, L.; Morassi-Bonzi, L.; Pinelli, P.; Remorini, D.; Degl'Innocenti, E.; Giordano, C.; Massai, R.; Agati, G. On the role of flavonoids in the integrated mechanisms of response of Ligustrum vulgare and Phillyrea latifolia to high solar radiation. New Phytol. 2005, 167 (2), 457-470.
34. Chupakhina, G.N.; Maslennikov, P.V. Plant Adaptation to Oil Stress. Russian J. Ecol. 2004, 35 (5), 290-295.