Hydrogen sulfide: Metabolic mediator or toxic gas?

Pediatric Critical Care Medicine

Volumn 9, Issue 1, 2008, Pages 129-130

  Tisherman, Samuel A ^a   Drabek, Tomas ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Hydrogen sulfide; Hypometabolism; Metabolic response; Tissue ischemia; Tissue oxygenation

Indexed keywords

HYDROGEN SULFIDE;

EDITORIAL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HUMAN; INDUCED HYPOTHERMIA; METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

EID: 38049103601     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.PCC.0000299823.48057.E4     Document Type: Editorial

References (10)

1. Random House Webster's College Dictionary. New York, Random House, 2001, p 1320
2. 2S induces a suspended animation-like state in mice. Science 2005; 308:518
3. Li J, Zhang G, Cai S, et al: Effect of inhaled hydrogen sulfide on metabolic responses in anesthetized, paralyzed, and mechanically ventilated piglets. Pediatr Crit Care Med 2008; 9:110-112
4. Zhang H, Zhi L, Moore PK, et al: Role of hydrogen sulfide in cecal ligation and puncture-induced sepsis in the mouse. Am J Physiol Lung Cell Mol Physiol 2006; 290:L1193-L1201
5. Zhang H, Zhi L, Moochhala S, et al: Hydrogen sulfide acts as an inflammatory mediator in cecal ligation and puncture-induced sepsis in mice by upregulating the production of cytokines and chemokines via NF-κ B. Am J Physiol Lung Cell Mol Physiol 2007; 292:L960-L971
6. Li L, Bhatia M, Zhu YZ, et al: Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J 2005; 19:1196-1198
7. Li L, Bhatia M, Moore PK: Hydrogen sulphide - A novel mediator of inflammation? Curr Opin Pharmacol 2006; 6:125-129
8. Zhao W, Zhang J, Lu Y, et al: The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener. EMBO J 2001; 20:6008-6016
9. Mok Y-YP, Atan MSBM, Ping CY, et al: Role of hydrogen sulphide in haemorrhagic shock in the rat: Protective effect of inhibitors of hydrogen sulphide biosynthesis. Br J Pharmacol 2004; 143:881-889
10. Sivarajah A, McDonald MC, Thiemermann C: The production of hydrogen sulfide limits myocardial ischemia and reperfusion injury and contributes to the cardioprotective effects of preconditioning with endotoxin, but not ischemia in the rat. Shock 2006; 26:154-161