Design, Preparation and in vitro Bioactivity of Mono-PEGylated Recombinant Hirudin

Chinese Journal of Chemical Engineering

Volumn 15, Issue 6, 2007, Pages 775-780

  HOU, Beibei ^a   LI, Shirong ^a   LI, Xiaohui ^a   XIU, Zhilong ^a  

^a DALIAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

anticoagulant activity; histidine residues; mono PEGylation; pH; r hirudin; SC mPEG

Indexed keywords

BIOACTIVITY; CARBONYLATION; CHROMATOGRAPHY; ELECTROPHORESIS; GLYCOLS; ION EXCHANGERS; MOLECULAR WEIGHT; POLYACRYLATES; POLYETHYLENES; SODIUM;

ANTICOAGULANT ACTIVITY; HISTIDINE RESIDUES; MONO-PEGYLATION; R-HIRUDIN;

ENZYME INHIBITION;

BIOACTIVITY; CARBONYLATION; CHROMATOGRAPHY; ELECTROPHORESIS; ENZYME INHIBITION; GLYCOLS; ION EXCHANGERS; MOLECULAR WEIGHT; POLYACRYLATES; POLYETHYLENES; SODIUM;

EID: 38049065326     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1004-9541(08)60001-4     Document Type: Article

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