CoolSim: Using industrial modeling techniques to examine the impact of selective head cooling in a model of perinatal regionalization

Pediatrics

Volumn 121, Issue 1, 2008, Pages 28-36

  Gray, James ^a,b   Geva, Alon ^a,b   Zheng, Zheng ^a,b   Zupancic, John A F ^a,b  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Discrete event simulation; Hypoxia ischemia; Infant; Newborn; Perinatal regionalization; Therapeutic hypothermia

Indexed keywords

AMPLITUDE INTEGRATED ELECTROENCEPHALOGRAPHY; ARTICLE; BRAIN ISCHEMIA; COOLING; COST CONTROL; DATA BASE; ELECTROENCEPHALOGRAM; ELECTROENCEPHALOGRAPHY; FOOD AND DRUG ADMINISTRATION; HEAD; HEAD COOLING DEVICE; HEALTH CARE COST; HEALTH CARE DELIVERY; HEALTH CARE POLICY; HUMAN; HYPOXIA; MAJOR CLINICAL STUDY; MATERIALS TESTING; MEDICAL DECISION MAKING; NEWBORN; OUTCOME ASSESSMENT; PERFORMANCE; PRIORITY JOURNAL; REGIONALIZATION; SAFETY; SIMULATION; UNITED STATES;

APGAR SCORE; BRAIN MAPPING; COST-BENEFIT ANALYSIS; DEVICE APPROVAL; ELECTROENCEPHALOGRAPHY; FEMALE; HEAD; HUMANS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; MALE; MODELS, ECONOMIC; PERINATAL CARE; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TERM BIRTH; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 38049060637     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2007-0633     Document Type: Article

References (25)

1. Gluckman PD, Wyatt JS, Azzopardi D, et al. Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet. 2005;365:663-670
2. Chung CA. Simulation Modeling Handbook: A Practical Approach. Boca Raton, FL: CRC Press; 2004
3. Kelton WD, Sadowski RP, Sturrock DT. Simulation With Arena. 3rd ed. New York, NY: McGraw-Hill; 2004
4. Caro JJ. Pharmacoeconomic analyses using discrete event simulation. Pharmacoeconomics. 2005;23:323-332
5. Stark AR. Levels of neonatal care. Pediatrics. 2004;114:1341-1347
6. al Naqeeb N, Edwards AD, Cowan FM, Azzopardi D. Assessment of neonatal encephalopathy by amplitude-integrated electroencephalography. Pediatrics. 1999;103:1263-1271
7. Toet MC, Hellstrom-Westas L, Groenendaal F, Eken P, de Vries LS. Amplitude integrated EEG 3 and 6 hours after birth in full term neonates with hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 1999;81:F19-F23
8. Massachusetts Department of Public Health. Massachusetts Community Health Information Profile (MassChip). Boston, MA: Massachusetts Department of Public Health; 2006. Available at: http://masschip.state.ma.us/. Accessed July 1, 2006
9. Hamilton BE, Martin JA, Ventura SJ, Sutton PD, Menacker F. Births: preliminary data for 2004. Natl Vital Stat Rep. 2005;54:1-17. Available at: www.cdc.gov/nchs/data/nvsr/nvsr54/nvsr54_08.pdf.
10. MapQuest. Available at: www.mapquest.com/directions/. Accessed June 6, 2006
11. McBride J, Parad R, Davis J, Allred L, Zupancic J. Cost analysis on the use of recombinant human superoxide dismutase (rhSOD) at birth in preterm infants to improve pulmonary outcome. Pediatr Res. 2005;57:1232
12. Zupancic JAF. A systematic review of costs associated with preterm birth. In: Behrman R, Stith-Butler A, eds. Preterm Birth: Causes, Consequences and Prevention. Washington, DC: National Academies Press; 2006
13. Centers for Medicare and Medicaid Services. Ambulance Fee Schedule public use file, 2006. Available at: www.cms.hhs.gov/AmbulanceFeeSchedule. Accessed July 1, 2006
14. Centers for Disease Control and Prevention. Economic costs associated with mental retardation, cerebral palsy, hearing loss, and vision impairment: United States, 2003. MMWR Morb Mort Wkly Rep. 2004;53:57-59
15. Bureau of Labor Statistics. Producer Price Index: general medical and surgical hospitals, 2006. Available at: www.bls.gov/ppi/#data. Accessed July 1, 2006
16. Bureau of Labor Statistics. Consumer Price Index: medical care, all urban consumers, northeast urban, 2006. Available at: www.bls.gov/cpi. Accessed July 1, 2006
17. Doubilet P, Begg CB, Weinstein MC, Braun P, McNeil BJ. Probabilistic sensitivity analysis using Monte Carlo simulation: a practical approach. Med Decis Making. 1985;5:157-177
18. Hutton JL, Pharoah PO. Life expectancy in severe cerebral palsy. Arch Dis Child. 2006;91:254-258
19. Arias E. United States life tables, 2003. Natl Vital Stat Rep. 2006;54:1-40
20. Furlong W, Feeny D, Torrance GW, et al. Multiplicative Multi-attribute Utility Function for the Health Utilities Index Mark 3 (HUI3) System: A Technical Report. Hamilton, Canada: McMaster University Center for Health Economics and Policy Analysis; 1998. Center for Health Economics and Policy Analysis Working Paper 98-11
21. Akisu M, Huseyinov A, Yalaz M, Cetin H, Kultursay N. Selective head cooling with hypothermia suppresses the generation of platelet-activating factor in cerebrospinal fluid of newborn infants with perinatal asphyxia. Prostaglandins Leukot Essent Fatty Acids. 2003;69:45-50
22. Battin MR, Penrice J, Gunn TR, Gunn AJ. Treatment of term infants with head cooling and mild systemic hypothermia (35.0°C and 34.5°C) after perinatal asphyxia. Pediatrics. 2003;111:244-251
23. Shankaran S, Laptook AR, Ehrenkranz RA, et al. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005;353:1574-1584
24. Gray JE, McCormick MC, Richardson DK, Ringer S. Normal birth weight intensive care unit survivors: outcome assessment. Pediatrics. 1996;97:832-838
25. Wyatt JS, Gluckman PD, Liu PY, et al., Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics. 2007;119:912-921